Values CatLog read from this paper
Functional Characterization of the SHIP1-Domains Regarding Their Contribution to Inositol 5-Phosphatase Activity
PMID 39858499doi:10.3390/biom15010105Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 7 records (21 values) from this paper: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 3.1.3.36, EC 3.1.3.56, EC 3.1.3.86
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 1729 | 0.03584 | 4.82 × 10⁴ | pH 7.2, 37 °C | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1)5PPase (5PPase domain construct) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 308.2 | 0.2937 | 1.05 × 10³ | pH 7.2, 37 °C | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) 5PPase (5PPase domain construct), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1)5PPase-C2 (5PPase-C2 domain construct) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 431.9 | 0.0276 | 1.56 × 10⁴ | pH 7.2, 37 °C | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) 5PPase-C2 (5PPase-C2 domain construct), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1)PHL-5PPase-C2 (PHL-5PPase-C2 domain construct) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 1036 | 0.1057 | 9.81 × 10³ | pH 7.2, 37 °C | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) PHL-5PPase-C2 (PHL-5PPase-C2 domain construct), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1)variant ΔPRR (SH2-linker-PHL-5PPase-C2) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 1456 | 0.05244 | 2.78 × 10⁴ | pH 7.2, 37 °C | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) variant ΔPRR (SH2-linker-PHL-5PPase-C2), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1)variant ΔSH2 (linker-PHL-5PPase-C2-PRR) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 989.4 | 0.01345 | 7.36 × 10⁴ | pH 7.2, 37 °C | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) variant ΔSH2 (linker-PHL-5PPase-C2-PRR), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1)variant ΔSH2-linker (PHL-5PPase-C2-PRR) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 1424 | 0.1239 | 1.15 × 10⁴ | pH 7.2, 37 °C | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) variant ΔSH2-linker (PHL-5PPase-C2-PRR), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |