EC 3.1.3.36: phosphoinositide 5-phosphatase
HydrolasesOpen in Browse
CatLog read 23 records for EC 3.1.3.36 from 2 papers, for 2 organisms. Names in these papers: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 19 records for EC 3.1.3.36 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.1.3.36 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2 | Schizosaccharomyces pombe | 16 |
| Functional Characterization of the SHIP1-Domains Regarding Their Contribution to Inositol 5-Phosphatase Activity | Homo sapiens | 7 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 1729 | 0.03584 | 4.82 × 10⁴ | pH 7.2, 37 °C | PMID 39858499 | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1)5PPase (5PPase domain construct) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 308.2 | 0.2937 | 1.05 × 10³ | pH 7.2, 37 °C | PMID 39858499 | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) 5PPase (5PPase domain construct), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1)5PPase-C2 (5PPase-C2 domain construct) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 431.9 | 0.0276 | 1.56 × 10⁴ | pH 7.2, 37 °C | PMID 39858499 | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) 5PPase-C2 (5PPase-C2 domain construct), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1)PHL-5PPase-C2 (PHL-5PPase-C2 domain construct) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 1036 | 0.1057 | 9.81 × 10³ | pH 7.2, 37 °C | PMID 39858499 | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) PHL-5PPase-C2 (PHL-5PPase-C2 domain construct), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1)variant ΔPRR (SH2-linker-PHL-5PPase-C2) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 1456 | 0.05244 | 2.78 × 10⁴ | pH 7.2, 37 °C | PMID 39858499 | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) variant ΔPRR (SH2-linker-PHL-5PPase-C2), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1)variant ΔSH2 (linker-PHL-5PPase-C2-PRR) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 989.4 | 0.01345 | 7.36 × 10⁴ | pH 7.2, 37 °C | PMID 39858499 | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) variant ΔSH2 (linker-PHL-5PPase-C2-PRR), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1)variant ΔSH2-linker (PHL-5PPase-C2-PRR) | Homo sapiens | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) | 1424 | 0.1239 | 1.15 × 10⁴ | pH 7.2, 37 °C | PMID 39858499 | Open record: SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1) variant ΔSH2-linker (PHL-5PPase-C2-PRR), 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | 1,2-dibutanoyl-sn-glycero-3-phospho-(1D-myo-inositol 3,4,5-trisphosphate) | — | — | 13 | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), 1,2-dibutanoyl-sn-glycero-3-phospho-(1D-myo-inositol 3,4,5-trisphosphate) |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | 1,2-dibutanoyl-sn-glycero-3-phospho-(1D-myo-inositol 3,5-bisphosphate) | — | — | 18.8 | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), 1,2-dibutanoyl-sn-glycero-3-phospho-(1D-myo-inositol 3,5-bisphosphate) |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | 1,2-dibutanoyl-sn-glycero-3-phospho-(1D-myo-inositol 4,5-bisphosphate) | — | — | 140 | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), 1,2-dibutanoyl-sn-glycero-3-phospho-(1D-myo-inositol 4,5-bisphosphate) |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | 3-O-methylfluorescein phosphate | 5.4 × 10⁻⁴ | 0.182 | 0.0030 calc. | pH 7, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), 3-O-methylfluorescein phosphate |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | 4-nitrophenyl phosphate | 0.00404 | 5.86 | 6.89 × 10⁻⁴ calc. | pH 7, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), 4-nitrophenyl phosphate |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | inositol 1,2,4,5,6-pentakisphosphate | — | — | 24.9 | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), inositol 1,2,4,5,6-pentakisphosphate |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | inositol 1,2,4,5-tetrakisphosphate | — | — | 46.6 | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), inositol 1,2,4,5-tetrakisphosphate |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | inositol 1,3,4,5-tetrakisphosphate | — | — | 8.78 | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), inositol 1,3,4,5-tetrakisphosphate |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | inositol 1,4,5-trisphosphateammonium molybdate inorganic phosphate assay | 11.2 | 0.0578 | 194 calc. | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), inositol 1,4,5-trisphosphate |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | inositol 1,4,5-trisphosphate | — | — | 208 | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), inositol 1,4,5-trisphosphate |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | inositol 2,4,5,6-tetrakisphosphate | — | — | 38.2 | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), inositol 2,4,5,6-tetrakisphosphate |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | inositol 2,4,5-trisphosphatein the text | 41.2 | 0.0109 | 3.78 × 10³ calc. | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), inositol 2,4,5-trisphosphate |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | inositol 2,4,5-trisphosphateTable III | — | — | 3.77 × 10³ | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), inositol 2,4,5-trisphosphate |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | inositol 4,5,6-trisphosphate | — | — | 79 | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), inositol 4,5,6-trisphosphate |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | inositol 4,5-bisphosphatein the text | 10.5 | 0.0759 | 138 calc. | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), inositol 4,5-bisphosphate |
| SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue) | Schizosaccharomyces pombe | inositol 4,5-bisphosphateTable III | — | — | 138 | pH 7.4, 30 °C | PMID 15316017 | Open record: SPsynaptojanin (inositol polyphosphate 5-phosphatase domain, synaptojanin homologue), inositol 4,5-bisphosphate |