Values CatLog read from this paper
A catalytic mechanism that explains a low catalytic activity of serine dehydratase like-1 from human cancer cells: crystal structure and site-directed mutagenesis studies
PMID 18342636doi:10.1016/j.bbagen.2008.01.020Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 24 records (72 values) from this paper: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells), hSDH (human liver L-serine dehydratase) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells) | Homo sapiens | L-serine | 10 | 30 | 0.33 | pH 8.3 | Open record: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells), L-serine |
| cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells) | Homo sapiens | L-threonine | 1.3 | 7 | 0.17 | pH 8.3 | Open record: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells), L-threonine |
| cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells)variant A172S | Homo sapiens | L-serine | 7 | 40 | 0.16 | pH 8.3 | Open record: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells) variant A172S, L-serine |
| cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells)variant A172S | Homo sapiens | L-threonine | 1.3 | 8 | 0.15 | pH 8.3 | Open record: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells) variant A172S, L-threonine |
| cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells)variant C309A | Homo sapiens | L-serine | 0.1 | 105 | 0.0013 | pH 8.3 | Open record: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells) variant C309A, L-serine |
| cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells)variant C309A | Homo sapiens | L-threonine | 0.1 | 125 | 7 × 10⁻⁴ | pH 8.3 | Open record: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells) variant C309A, L-threonine |
| cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells)variant G72A | Homo sapiens | L-serine | 4 | 30 | 0.14 | pH 8.3 | Open record: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells) variant G72A, L-serine |
| cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells)variant G72A | Homo sapiens | L-threonine | 15 | 4 | 3.5 | pH 8.3 | Open record: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells) variant G72A, L-threonine |
| cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells)variant G72A/S228A | Homo sapiens | L-serine | 13 | 35 | 0.38 | pH 8.3 | Open record: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells) variant G72A/S228A, L-serine |
| cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells)variant G72A/S228A | Homo sapiens | L-threonine | 12 | 9 | 1.4 | pH 8.3 | Open record: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells) variant G72A/S228A, L-threonine |
| cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells)variant S228A | Homo sapiens | L-serine | 1.5 | 33 | 0.046 | pH 8.3 | Open record: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells) variant S228A, L-serine |
| cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells)variant S228A | Homo sapiens | L-threonine | 0.3 | 19 | 0.015 | pH 8.3 | Open record: cSDH (serine dehydratase-like 1, SDH isoform from human cancer cells) variant S228A, L-threonine |
| hSDH (human liver L-serine dehydratase) | Homo sapiens | L-serine | 79 | 23 | 3.5 | pH 8.3 | Open record: hSDH (human liver L-serine dehydratase), L-serine |
| hSDH (human liver L-serine dehydratase) | Homo sapiens | L-threonine | 71 | 31 | 2.3 | pH 8.3 | Open record: hSDH (human liver L-serine dehydratase), L-threonine |
| hSDH (human liver L-serine dehydratase)variant A222S | Homo sapiens | L-serine | 62 | 22 | 2.9 | pH 8.3 | Open record: hSDH (human liver L-serine dehydratase) variant A222S, L-serine |
| hSDH (human liver L-serine dehydratase)variant A222S | Homo sapiens | L-threonine | 61 | 23 | 2.6 | pH 8.3 | Open record: hSDH (human liver L-serine dehydratase) variant A222S, L-threonine |
| hSDH (human liver L-serine dehydratase)variant A65G | Homo sapiens | L-serine | 11 | 49 | 0.22 | pH 8.3 | Open record: hSDH (human liver L-serine dehydratase) variant A65G, L-serine |
| hSDH (human liver L-serine dehydratase)variant A65G | Homo sapiens | L-threonine | 4 | 43 | 0.087 | pH 8.3 | Open record: hSDH (human liver L-serine dehydratase) variant A65G, L-threonine |
| hSDH (human liver L-serine dehydratase)variant A65G/A222S | Homo sapiens | L-serine | 24 | 22 | 1 | pH 8.3 | Open record: hSDH (human liver L-serine dehydratase) variant A65G/A222S, L-serine |
| hSDH (human liver L-serine dehydratase)variant A65G/A222S | Homo sapiens | L-threonine | 10 | 22 | 0.41 | pH 8.3 | Open record: hSDH (human liver L-serine dehydratase) variant A65G/A222S, L-threonine |
| hSDH (human liver L-serine dehydratase)variant C303A | Homo sapiens | L-serine | 7 | 133 | 0.05 | pH 8.3 | Open record: hSDH (human liver L-serine dehydratase) variant C303A, L-serine |
| hSDH (human liver L-serine dehydratase)variant C303A | Homo sapiens | L-threonine | 1.7 | 108 | 0.016 | pH 8.3 | Open record: hSDH (human liver L-serine dehydratase) variant C303A, L-threonine |
| hSDH (human liver L-serine dehydratase)variant S166A | Homo sapiens | L-serine | 105 | 56 | 1.9 | pH 8.3 | Open record: hSDH (human liver L-serine dehydratase) variant S166A, L-serine |
| hSDH (human liver L-serine dehydratase)variant S166A | Homo sapiens | L-threonine | 82 | 50 | 1.6 | pH 8.3 | Open record: hSDH (human liver L-serine dehydratase) variant S166A, L-threonine |