Values CatLog read from this paper
Substrate specificities of caspase family proteases
PMID 9092497doi:10.1074/jbc.272.15.9677Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 46 records (120 values) from this paper: caspase-3, caspase-7, caspase-1 and 3 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 3.4.22.36, EC 3.4.22.55, EC 3.4.22.56, EC 3.4.22.57, EC 3.4.22.60
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| caspase-1variant D381E | — | acetyl-Asp-Gln-Met-Asp p-nitroanilide | 0.94 | 0.045 | 21 | pH 7.5 | Open record: caspase-1 variant D381E, acetyl-Asp-Gln-Met-Asp p-nitroanilide |
| caspase-1variant D381E | — | acetyl-Asp-Glu-Val-Asp p-nitroanilide | 0.5 | 0.018 | 30 | pH 7.5 | Open record: caspase-1 variant D381E, acetyl-Asp-Glu-Val-Asp p-nitroanilide |
| caspase-1variant D381E | — | acetyl-Leu-Glu-Val-Asp p-nitroanilide | 0.4 | 0.0085 | 54 | pH 7.5 | Open record: caspase-1 variant D381E, acetyl-Leu-Glu-Val-Asp p-nitroanilide |
| caspase-1variant D381E | — | acetyl-Tyr-Glu-Val-Asp p-nitroanilide | 0.57 | 0.0073 | 79 | pH 7.5 | Open record: caspase-1 variant D381E, acetyl-Tyr-Glu-Val-Asp p-nitroanilide |
| caspase-1variant D381E | — | acetyl-Tyr-Glu-Val-Asp-Gly-Trp amide | — | 0.105 | — | pH 7.5 | Open record: caspase-1 variant D381E, acetyl-Tyr-Glu-Val-Asp-Gly-Trp amide |
| caspase-1variant D381E | — | acetyl-Tyr-Val-Ala-Asp p-nitroanilide | 1.5 | 0.023 | 63 | pH 7.5 | Open record: caspase-1 variant D381E, acetyl-Tyr-Val-Ala-Asp p-nitroanilide |
| caspase-1variant D381E | — | acetyl-Val-Gln-Val-Asp p-nitroanilide | 0.33 | 0.12 | 2.8 | pH 7.5 | Open record: caspase-1 variant D381E, acetyl-Val-Gln-Val-Asp p-nitroanilide |
| caspase-1variant D381E | — | acetyl-Val-Glu-Ile-Asp p-nitroanilide | 0.56 | 0.046 | 12 | pH 7.5 | Open record: caspase-1 variant D381E, acetyl-Val-Glu-Ile-Asp p-nitroanilide |
| caspase-2 | — | acetyl-Val-Asp-Gln-Gln-Asp p-nitroanilide | 8 | 0.53 | 15 | pH 7.5 | Open record: caspase-2, acetyl-Val-Asp-Gln-Gln-Asp p-nitroanilide |
| caspase-2 | — | acetyl-Val-Asp-Val-Ala-Asp aminomethylcoumarin | — | 0.08 | — | pH 7.5 | Open record: caspase-2, acetyl-Val-Asp-Val-Ala-Asp aminomethylcoumarin |
| caspase-2 | — | acetyl-Val-Asp-Val-Ala-Asp p-nitroanilide | 4.5 | 0.053 | 84 | pH 7.5 | Open record: caspase-2, acetyl-Val-Asp-Val-Ala-Asp p-nitroanilide |
| caspase-2 | — | acetyl-Val-Asp-Val-Ala-Asp-Gly-Trp amide | — | 0.15 | — | pH 6.2 | Open record: caspase-2, acetyl-Val-Asp-Val-Ala-Asp-Gly-Trp amide |
| caspase-3 | — | acetyl-Asp-Gln-Met-Asp p-nitroanilide | 11 | 0.044 | 262 | pH 7.5 | Open record: caspase-3, acetyl-Asp-Gln-Met-Asp p-nitroanilide |
| caspase-3 | — | acetyl-Asp-Glu-Val-Asp aminomethylcoumarin | — | 0.01 | — | pH 7.5 | Open record: caspase-3, acetyl-Asp-Glu-Val-Asp aminomethylcoumarin |
| caspase-3 | — | acetyl-Asp-Glu-Val-Asp p-nitroanilide | 2.4 | 0.011 | 218 | pH 7.5 | Open record: caspase-3, acetyl-Asp-Glu-Val-Asp p-nitroanilide |
| caspase-3 | — | acetyl-Tyr-Glu-Val-Asp p-nitroanilide | 14.1 | 0.37 | 39 | pH 7.5 | Open record: caspase-3, acetyl-Tyr-Glu-Val-Asp p-nitroanilide |
| caspase-3 | — | acetyl-Tyr-Val-Ala-Asp p-nitroanilide | 3 | 29 | 0.1 | pH 7.5 | Open record: caspase-3, acetyl-Tyr-Val-Ala-Asp p-nitroanilide |
| caspase-3 | — | acetyl-Val-Asp-Gln-Met-Asp-Gly-Trp amide | — | 0.2 | — | pH 7.5 | Open record: caspase-3, acetyl-Val-Asp-Gln-Met-Asp-Gly-Trp amide |
| caspase-3 | — | acetyl-Val-Asp-Val-Ala-Asp p-nitroanilide | 5.1 | 0.067 | 76 | pH 7.5 | Open record: caspase-3, acetyl-Val-Asp-Val-Ala-Asp p-nitroanilide |
| caspase-3 | — | acetyl-Val-Gln-Val-Asp p-nitroanilide | 15 | 0.51 | 29 | pH 7.5 | Open record: caspase-3, acetyl-Val-Gln-Val-Asp p-nitroanilide |
| caspase-3 | — | acetyl-Val-Glu-Ile-Asp p-nitroanilide | 16 | 0.25 | 61 | pH 7.5 | Open record: caspase-3, acetyl-Val-Glu-Ile-Asp p-nitroanilide |
| caspase-4 | — | acetyl-Asp-Gln-Met-Asp p-nitroanilide | 0.09 | 0.35 | 0.27 | pH 7.5 | Open record: caspase-4, acetyl-Asp-Gln-Met-Asp p-nitroanilide |
| caspase-4 | — | acetyl-Asp-Glu-Val-Asp p-nitroanilide | 0.05 | 0.032 | 1.8 | pH 7.5 | Open record: caspase-4, acetyl-Asp-Glu-Val-Asp p-nitroanilide |
| caspase-4 | — | acetyl-Leu-Glu-Val-Asp p-nitroanilide | 0.14 | 0.044 | 3.2 | pH 7.5 | Open record: caspase-4, acetyl-Leu-Glu-Val-Asp p-nitroanilide |
| caspase-4 | — | acetyl-Leu-Glu-Val-Asp-Gly-Trp amide | — | 0.43 | — | pH 7.5 | Open record: caspase-4, acetyl-Leu-Glu-Val-Asp-Gly-Trp amide |
| caspase-4 | — | acetyl-Tyr-Glu-Val-Asp p-nitroanilide | 0.08 | 0.031 | 2.6 | pH 7.5 | Open record: caspase-4, acetyl-Tyr-Glu-Val-Asp p-nitroanilide |
| caspase-4 | — | acetyl-Tyr-Val-Ala-Asp p-nitroanilide | 0.24 | 0.874 | 0.28 | pH 7.5 | Open record: caspase-4, acetyl-Tyr-Val-Ala-Asp p-nitroanilide |
| caspase-4 | — | acetyl-Val-Gln-Val-Asp p-nitroanilide | 0.12 | 0.72 | 0.17 | pH 7.5 | Open record: caspase-4, acetyl-Val-Gln-Val-Asp p-nitroanilide |
| caspase-4 | — | acetyl-Val-Glu-Ile-Asp p-nitroanilide | 0.15 | 0.205 | 0.75 | pH 7.5 | Open record: caspase-4, acetyl-Val-Glu-Ile-Asp p-nitroanilide |
| caspase-6 (Mch2α) | — | acetyl-Asp-Gln-Met-Asp p-nitroanilide | 0.3 | 1.3 | 0.23 | pH 7.5 | Open record: caspase-6 (Mch2α), acetyl-Asp-Gln-Met-Asp p-nitroanilide |
| caspase-6 (Mch2α) | — | acetyl-Asp-Glu-Val-Asp p-nitroanilide | 0.4 | 0.18 | 2 | pH 7.5 | Open record: caspase-6 (Mch2α), acetyl-Asp-Glu-Val-Asp p-nitroanilide |
| caspase-6 (Mch2α) | — | acetyl-Leu-Glu-Val-Asp p-nitroanilide | 6.8 | 0.16 | 42 | pH 7.5 | Open record: caspase-6 (Mch2α), acetyl-Leu-Glu-Val-Asp p-nitroanilide |
| caspase-6 (Mch2α) | — | acetyl-Tyr-Glu-Val-Asp p-nitroanilide | 0.1 | 1.2 | 0.09 | pH 7.5 | Open record: caspase-6 (Mch2α), acetyl-Tyr-Glu-Val-Asp p-nitroanilide |
| caspase-6 (Mch2α) | — | acetyl-Val-Asp-Gln-Gln-Asp p-nitroanilide | 0.08 | 7 | 0.011 | pH 7.5 | Open record: caspase-6 (Mch2α), acetyl-Val-Asp-Gln-Gln-Asp p-nitroanilide |
| caspase-6 (Mch2α) | — | acetyl-Val-Gln-Val-Asp p-nitroanilide | 7.1 | 0.58 | 12 | pH 7.5 | Open record: caspase-6 (Mch2α), acetyl-Val-Gln-Val-Asp p-nitroanilide |
| caspase-6 (Mch2α) | — | acetyl-Val-Gln-Val-Asp-Gly-Trp amide | — | 0.13 | — | pH 7.5 | Open record: caspase-6 (Mch2α), acetyl-Val-Gln-Val-Asp-Gly-Trp amide |
| caspase-6 (Mch2α) | — | acetyl-Val-Glu-Ile-Asp p-nitroanilide | 5 | 0.03 | 168 | pH 7.5 | Open record: caspase-6 (Mch2α), acetyl-Val-Glu-Ile-Asp p-nitroanilide |
| caspase-7 | — | acetyl-Asp-Gln-Met-Asp p-nitroanilide | 3.2 | 0.13 | 25 | pH 7.5 | Open record: caspase-7, acetyl-Asp-Gln-Met-Asp p-nitroanilide |
| caspase-7 | — | acetyl-Asp-Glu-Val-Asp aminomethylcoumarin | — | 0.011 | — | pH 7.5 | Open record: caspase-7, acetyl-Asp-Glu-Val-Asp aminomethylcoumarin |
| caspase-7 | — | acetyl-Asp-Glu-Val-Asp p-nitroanilide | 0.43 | 0.012 | 37 | pH 7.5 | Open record: caspase-7, acetyl-Asp-Glu-Val-Asp p-nitroanilide |
| caspase-7 | — | acetyl-Tyr-Glu-Val-Asp p-nitroanilide | 6.9 | 0.49 | 14 | pH 7.5 | Open record: caspase-7, acetyl-Tyr-Glu-Val-Asp p-nitroanilide |
| caspase-7 | — | acetyl-Val-Asp-Gln-Gln-Asp p-nitroanilide | 4.8 | 3.1 | 1.6 | pH 7.5 | Open record: caspase-7, acetyl-Val-Asp-Gln-Gln-Asp p-nitroanilide |
| caspase-7 | — | acetyl-Val-Asp-Gln-Val-Asp-Gly-Trp amide | — | 0.125 | — | pH 7.5 | Open record: caspase-7, acetyl-Val-Asp-Gln-Val-Asp-Gly-Trp amide |
| caspase-7 | — | acetyl-Val-Asp-Val-Ala-Asp p-nitroanilide | 2.6 | 0.2 | 13 | pH 7.5 | Open record: caspase-7, acetyl-Val-Asp-Val-Ala-Asp p-nitroanilide |
| caspase-7 | — | acetyl-Val-Gln-Val-Asp p-nitroanilide | 6.2 | 2.1 | 3 | pH 7.5 | Open record: caspase-7, acetyl-Val-Gln-Val-Asp p-nitroanilide |
| caspase-7 | — | acetyl-Val-Glu-Ile-Asp p-nitroanilide | 3.74 | 0.57 | 6.6 | pH 7.5 | Open record: caspase-7, acetyl-Val-Glu-Ile-Asp p-nitroanilide |