Values CatLog read from this paper
Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl-CoA reductase. Characterization and chemical modification
PMID 2681185doi:10.1016/s0021-9258(19)84659-8Open in Browse
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CatLog read 11 records (11 values) from this paper: HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase) from Pseudomonas mevalonii.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase) | Pseudomonas mevalonii | (R,S)-3-hydroxy-3-methylglutaryl coenzyme A | — | 0.3 | — | pH 8.1, 37 °C | Open record: HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase), (R,S)-3-hydroxy-3-methylglutaryl coenzyme A |
| HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase) | Pseudomonas mevalonii | (R,S)-mevaldehydeReaction c; 0.48 mM NADH; cosubstrate NADH | — | 36 | — | pH 8.1, 37 °C | Open record: HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase), (R,S)-mevaldehyde |
| HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase) | Pseudomonas mevalonii | (R,S)-mevaldehydeReaction c*; 1.0 mM CoASH; 0.48 mM NADH; cosubstrate NADH | — | 2.91 | — | pH 8.1, 37 °C | Open record: HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase), (R,S)-mevaldehyde |
| HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase) | Pseudomonas mevalonii | (R,S)-mevaldehydeReaction d; 1.0 mM CoASH; 3.0 mM NAD+ | — | 1.36 | — | pH 8.1, 37 °C | Open record: HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase), (R,S)-mevaldehyde |
| HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase) | Pseudomonas mevalonii | (R,S)-mevalonate | — | 0.22 | — | pH 8.1, 37 °C | Open record: HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase), (R,S)-mevalonate |
| HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase) | Pseudomonas mevalonii | coenzyme AReaction a; standard concentrations 3.7 mM (R,S)-mevalonate | — | 0.05 | — | pH 8.1, 37 °C | Open record: HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase), coenzyme A |
| HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase) | Pseudomonas mevalonii | coenzyme AReaction d; standard concentrations 5.0 mM (R,S)-mevaldehyde | — | 0.6 | — | pH 8.1, 37 °C | Open record: HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase), coenzyme A |
| HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase) | Pseudomonas mevalonii | NAD+Reaction a; standard concentrations 3.7 mM (R,S)-mevalonate | — | 0.37 | — | pH 8.1, 37 °C | Open record: HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase), NAD+ |
| HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase) | Pseudomonas mevalonii | NAD+Reaction d; standard concentrations 5.0 mM (R,S)-mevaldehyde | — | 0.17 | — | pH 8.1, 37 °C | Open record: HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase), NAD+ |
| HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase) | Pseudomonas mevalonii | NADHReaction b; standard concentrations 1.0 mM (R,S)-HMG-CoA | — | 0.17 | — | pH 8.1, 37 °C | Open record: HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase), NADH |
| HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase) | Pseudomonas mevalonii | NADHReaction c*; 1.0 mM CoASH; cosubstrate (R,S)-mevaldehyde | — | 0.03 | — | pH 8.1, 37 °C | Open record: HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase), NADH |