Values CatLog read from this paper
Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine
PMID 20971807doi:10.1124/mol.110.068494Open in Browse
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CatLog read 6 records (18 values) from this paper: butyrylcholinesterase from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| butyrylcholinesterase | Homo sapiens | acetylcholine | 1.43 × 10³ | 0.148 | 9.7 × 10³ | 25 °C | Open record: butyrylcholinesterase, acetylcholine |
| butyrylcholinesterasevariant A199S/F227A/S287G/A328W/E441D | Homo sapiens | (-)-cocaine | 28.8 | 0.0011 | 2.7 × 10⁴ | 25 °C | Open record: butyrylcholinesterase variant A199S/F227A/S287G/A328W/E441D, (-)-cocaine |
| butyrylcholinesterasevariant A199S/F227A/S287G/A328W/E441D | Homo sapiens | acetylcholine | 243 | 0.027 | 9 × 10³ | 25 °C | Open record: butyrylcholinesterase variant A199S/F227A/S287G/A328W/E441D, acetylcholine |
| butyrylcholinesterasevariant A199S/F227A/S287G/A328W/Y332G/E441D | Homo sapiens | (-)-cocaine | 73.8 | 0.0035 | 2.2 × 10⁴ | 25 °C | Open record: butyrylcholinesterase variant A199S/F227A/S287G/A328W/Y332G/E441D, (-)-cocaine |
| butyrylcholinesterasevariant A199S/F227A/S287G/A328W/Y332G/E441D | Homo sapiens | acetylcholine | 230 | 0.075 | 3 × 10³ | 25 °C | Open record: butyrylcholinesterase variant A199S/F227A/S287G/A328W/Y332G/E441D, acetylcholine |
| butyrylcholinesterasevariant A199S/S287G/A328W/Y332G | Homo sapiens | acetylcholine | 125 | 0.036 | 3.5 × 10³ | 25 °C | Open record: butyrylcholinesterase variant A199S/S287G/A328W/Y332G, acetylcholine |