Values CatLog read from this paper
Purification, reconstitution, and steady-state kinetics of the trans-membrane 17 beta-hydroxysteroid dehydrogenase 2
PMID 11940569doi:10.1074/jbc.m111726200Open in Browse
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CatLog read 9 records (27 values) from this paper: 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2) | Homo sapiens | (20S)-20-hydroxypregn-4-en-3-one | 0.78 | 5.3 × 10⁻⁴ | 1.5 × 10³ | pH 7.4, 37 °C | Open record: 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2), (20S)-20-hydroxypregn-4-en-3-one |
| 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2) | Homo sapiens | Dihydrotestosterone | 2.4 | 2.5 × 10⁻⁴ | 1 × 10⁴ | pH 7.4, 37 °C | Open record: 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2), Dihydrotestosterone |
| 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2) | Homo sapiens | Estradiol | 3.9 | 3.5 × 10⁻⁴ | 1.1 × 10⁴ | pH 7.4, 37 °C | Open record: 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2), Estradiol |
| 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2) | Homo sapiens | NAD10 µM estradiol constant; cosubstrate Estradiol | 4.7 | 0.11 | 40 | pH 7.4, 37 °C | Open record: 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2), NAD |
| 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2) | Homo sapiens | NAD10 µM testosterone constant; cosubstrate Testosterone | 2.9 | 0.167 | 20 | pH 7.4, 37 °C | Open record: 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2), NAD |
| 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2) | Homo sapiens | NADH10 µM estrone constant; cosubstrate Estrone | 0.33 | 0.0056 | 60 | pH 7.4, 37 °C | Open record: 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2), NADH |
| 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2) | Homo sapiens | NADH10 µM androstenedione constant | 0.27 | 0.0053 | 50 | pH 7.4, 37 °C | Open record: 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2), NADH |
| 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2) | Homo sapiens | NADP | 1.3 | 9.6 | 0.1 | pH 7.4, 37 °C | Open record: 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2), NADP |
| 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2) | Homo sapiens | Testosterone | 3.4 | 6.1 × 10⁻⁴ | 5.5 × 10³ | pH 7.4, 37 °C | Open record: 17β-hydroxysteroid dehydrogenase 2 (17β-HSD2), Testosterone |