Values CatLog read from this paper
A human-like glutaminase-free asparaginase is highly efficacious in ASNSlow leukemia and solid cancer mouse xenograft models
PMID 39709177doi:10.1016/j.canlet.2024.217404Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 3 records (6 values) from this paper: L-asparaginase (L-ASNase), L-asparaginase (asparaginase, EBD-200) from Escherichia coli, Cavia porcellus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 3 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| L-asparaginase (asparaginase, EBD-200)variant EBD-200 (humanized GpA369: surface and T-cell-epitope residues mutated to the human asparaginase sequence) | Cavia porcellus | L-asparagine | 61.7 | 0.0413 | 1.49 × 10³ calc. | pH 7.5, 37 °C | Open record: L-asparaginase (asparaginase, EBD-200) variant EBD-200 (humanized GpA369: surface and T-cell-epitope residues mutated to the human asparaginase sequence), L-asparagine |
| L-asparaginase (L-ASNase) | Escherichia coli | L-asparagine | 44 | 0.014 | 3.1 × 10³ calc. | pH 7.5, 37 °C | Open record: L-asparaginase (L-ASNase), L-asparagine |
| L-asparaginase (L-ASNase)variant Q59L | Escherichia coli | L-asparagine | 1.3 | 1.4 | 0.93 calc. | pH 7.5, 37 °C | Open record: L-asparaginase (L-ASNase) variant Q59L, L-asparagine |