Values CatLog read from this paper
Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates
PMID 33139728doi:10.1038/s41467-020-19321-8Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 40 records (75 values) from this paper: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) from Saccharomyces cerevisiae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 35 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | acetyl coenzyme A | — | 0.03 | — | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), acetyl coenzyme A |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Ala-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 5.1 | 0.08 | 64 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Ala-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Arg-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.135 | 0.45 | 0.30 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Arg-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Glu-Arg-Phe-Val-Gly-Ser-Arg-Arg-Arg | 10.3 | 0.27 | 38 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Glu-Arg-Phe-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Glu-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 4 | 6 | 0.67 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Glu-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Leu-Arg-Glu-Val-Gly-Ser-Arg-Arg-Arg | 1.01 | 1.7 | 0.59 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Leu-Arg-Glu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Leu-Arg-Phe-Glu-Gly-Ser-Arg-Arg-Arg | 8.3 | — | — | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Leu-Arg-Phe-Glu-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Leu-Arg-Phe-Val-Gly-Ser-Arg-Arg-Arg | 12 | — | — | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Leu-Arg-Phe-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Leu-Glu-Phe-Val-Gly-Ser-Arg-Arg-Arg | 0.72 | 3.8 | 0.19 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Leu-Glu-Phe-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Leu-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 5.6 | 0.73 | 7.7 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Leu-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Lys-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.35 | 1.19 | 0.29 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Lys-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Phe-Ala-Leu-Val-Gly-Ser-Arg-Arg-Arg | 6.9 | — | — | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Phe-Ala-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Phe-Arg-Leu-Val-Gly-Ser-Arg-Arg-Arg | 9 | 0.027 | 330 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Phe-Arg-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Phe-Glu-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.18 | 3.6 | 0.050 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Phe-Glu-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Phe-His-Ala-Val-Gly-Ser-Arg-Arg-Arg | 8 | — | — | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Phe-His-Ala-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Phe-His-Glu-Val-Gly-Ser-Arg-Arg-Arg | 3.2 | 2.1 | 1.5 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Phe-His-Glu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Phe-His-Leu-Glu-Gly-Ser-Arg-Arg-Arg | 6.7 | 0.62 | 11 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Phe-His-Leu-Glu-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 4.2 | 0.14 | 30 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Phe-His-Phe-Val-Gly-Ser-Arg-Arg-Arg | 10 | 0.028 | 360 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Phe-His-Phe-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Trp-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 3.4 | 0.14 | 24 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Trp-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Tyr-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 2.5 | 0.52 | 4.8 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Tyr-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) | Saccharomyces cerevisiae | Met-Tyr-Thr-Leu-Leu-Gly-Ser-Arg-Arg-Arg | 3.2 | 0.19 | 17 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38), Met-Tyr-Thr-Leu-Leu-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant E118A | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.4 | 0.32 | 1.2 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant E118A, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant E118Q | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.6 | 0.43 | 1.4 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant E118Q, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant E120A | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.88 | 0.26 | 3.4 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant E120A, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant E120Q | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 1.01 | 0.3 | 3.4 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant E120Q, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant E29A | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.24 | 0.16 | 1.5 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant E29A, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant E29Q | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.18 | 0.25 | 0.72 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant E29Q, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant F47A | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 2.3 | 0.16 | 14 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant F47A, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant K500A/K501A/K503A/K504A | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 4.2 | 0.18 | 23 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant K500A/K501A/K503A/K504A, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant K59A | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 2.2 | 0.191 | 12 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant K59A, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant L27A | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.01 | 0.08 | 0.12 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant L27A, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant S28A | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 1.8 | 0.27 | 6.7 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant S28A, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant Y130A | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.057 | 0.2 | 0.28 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant Y130A, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant Y130F | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.08 | 0.12 | 0.67 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant Y130F, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant Y145F | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 1.02 | 0.23 | 4.4 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant Y145F, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant Y31F | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.45 | 0.23 | 2.0 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant Y31F, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant Y80A | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 2.5 | 0.55 | 4.5 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant Y80A, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant Y80F | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 1.68 | 0.43 | 3.9 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant Y80F, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |
| NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38)variant ΔNaa38 | Saccharomyces cerevisiae | Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg | 0.27 | 0.11 | 2.5 calc. | pH 7.5, 25 °C | Open record: NatC (heterotrimeric N-terminal acetyltransferase C: Naa30-Naa35-Naa38) variant ΔNaa38, Met-Phe-His-Leu-Val-Gly-Ser-Arg-Arg-Arg |