Values CatLog read from this paper
The zymogenic form of SARS-CoV-2 main protease: A discrete target for drug discovery
PMID 39675720doi:10.1016/j.jbc.2024.108079Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 2 records (4 values) from this paper: main protease (Mpro, nsp5) from severe acute respiratory syndrome coronavirus 2.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 2 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| main protease (Mpro, nsp5) | severe acute respiratory syndrome coronavirus 2 | Dabcyl-Asn-Arg-Abu-Orn-Leu-Gln-Ser-Gly-Asn-Ser-Arg-Lys-Edans | 0.51 | 0.0514 | 9.9 calc. | pH 7.5, 30 °C | Open record: main protease (Mpro, nsp5), Dabcyl-Asn-Arg-Abu-Orn-Leu-Gln-Ser-Gly-Asn-Ser-Arg-Lys-Edans |
| main protease (Mpro, nsp5)variant Q-1I | severe acute respiratory syndrome coronavirus 2 | Dabcyl-Asn-Arg-Abu-Orn-Leu-Gln-Ser-Gly-Asn-Ser-Arg-Lys-Edans | 3.7 × 10⁻⁴ | 0.08 | 0.0046 calc. | pH 7.5, 30 °C | Open record: main protease (Mpro, nsp5) variant Q-1I, Dabcyl-Asn-Arg-Abu-Orn-Leu-Gln-Ser-Gly-Asn-Ser-Arg-Lys-Edans |