Values CatLog read from this paper

Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases

PMID 25422158doi:10.1002/pro.2607Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 5 records (10 values) from this paper: mevalonate-3-kinase (M3K) from Thermoplasma acidophilum.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 5 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 2.7.1.185

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
mevalonate-3-kinase (M3K)Thermoplasma acidophilum(R)-mevalonate5.30.1341 calc.pH 8.5, 55 °COpen record: mevalonate-3-kinase (M3K), (R)-mevalonate
mevalonate-3-kinase (M3K)variant L18AThermoplasma acidophilum(R)-mevalonate5.13.11.6 calc.pH 8.5, 55 °COpen record: mevalonate-3-kinase (M3K) variant L18A, (R)-mevalonate
mevalonate-3-kinase (M3K)variant R185KThermoplasma acidophilum(R)-mevalonate0.311.680.18 calc.pH 8.5, 55 °COpen record: mevalonate-3-kinase (M3K) variant R185K, (R)-mevalonate
mevalonate-3-kinase (M3K)variant S105AThermoplasma acidophilum(R)-mevalonate1.160.274.3 calc.pH 8.5, 55 °COpen record: mevalonate-3-kinase (M3K) variant S105A, (R)-mevalonate
mevalonate-3-kinase (M3K)variant T275AThermoplasma acidophilum(R)-mevalonate5.80.599.8 calc.pH 8.5, 55 °COpen record: mevalonate-3-kinase (M3K) variant T275A, (R)-mevalonate