Values CatLog read from this paper
Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major
PMID 25978379doi:10.1371/journal.pntd.0003781Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 7 records (21 values) from this paper: thymidine kinase (LmTK, type II TK) from Leishmania major.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| thymidine kinase (LmTK, type II TK) | Leishmania major | 2'-deoxythymidine (thymidine) | 2.62 | 0.0011 | 2.38 × 10³ | pH 7.4, 25 °C | Open record: thymidine kinase (LmTK, type II TK), 2'-deoxythymidine (thymidine) |
| thymidine kinase (LmTK, type II TK) | Leishmania major | 2'-deoxyuridine | 3.06 | 0.0111 | 276 | pH 7.4, 25 °C | Open record: thymidine kinase (LmTK, type II TK), 2'-deoxyuridine |
| thymidine kinase (LmTK, type II TK) | Leishmania major | 3'-azido-3'-deoxythymidine (zidovudine) | 1.97 | 0.00304 | 651 | pH 7.4, 25 °C | Open record: thymidine kinase (LmTK, type II TK), 3'-azido-3'-deoxythymidine (zidovudine) |
| thymidine kinase (LmTK, type II TK) | Leishmania major | 5-bromo-2'-deoxyuridine | 3.47 | 0.00205 | 1.69 × 10³ | pH 7.4, 25 °C | Open record: thymidine kinase (LmTK, type II TK), 5-bromo-2'-deoxyuridine |
| thymidine kinase (LmTK, type II TK) | Leishmania major | 5-fluoro-2'-deoxyuridine | 4.66 | 0.00572 | 814 | pH 7.4, 25 °C | Open record: thymidine kinase (LmTK, type II TK), 5-fluoro-2'-deoxyuridine |
| thymidine kinase (LmTK, type II TK) | Leishmania major | 5-hydroxymethyl-2'-deoxyuridine | 2.82 | 0.0967 | 29.1 | pH 7.4, 25 °C | Open record: thymidine kinase (LmTK, type II TK), 5-hydroxymethyl-2'-deoxyuridine |
| thymidine kinase (LmTK, type II TK) | Leishmania major | uridine | 0.44 | 1.462 | 0.303 | pH 7.4, 25 °C | Open record: thymidine kinase (LmTK, type II TK), uridine |