Values CatLog read from this paper
Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target
PMID 30098336doi:10.1016/j.jmb.2018.07.030Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (12 values) from this paper: Pf6PGD (6-phosphogluconate dehydrogenase), h6PGD (6-phosphogluconate dehydrogenase) from Plasmodium falciparum, Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 6 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| h6PGD (6-phosphogluconate dehydrogenase) | Homo sapiens | 6-phosphogluconate | 22.2 | 0.0337 | 659 calc. | pH 8, 25 °C | Open record: h6PGD (6-phosphogluconate dehydrogenase), 6-phosphogluconate |
| h6PGD (6-phosphogluconate dehydrogenase) | Homo sapiens | nicotinamide adenine dinucleotide phosphate (oxidized) | 21.4 | 0.0069 | 3.1 × 10³ calc. | pH 8, 25 °C | Open record: h6PGD (6-phosphogluconate dehydrogenase), nicotinamide adenine dinucleotide phosphate (oxidized) |
| Pf6PGD (6-phosphogluconate dehydrogenase) | Plasmodium falciparum | 6-phosphogluconate | 7.1 | 0.0113 | 630 calc. | pH 8, 25 °C | Open record: Pf6PGD (6-phosphogluconate dehydrogenase), 6-phosphogluconate |
| Pf6PGD (6-phosphogluconate dehydrogenase) | Plasmodium falciparum | nicotinamide adenine dinucleotide phosphate (oxidized) | 7.6 | 0.009 | 840 calc. | pH 8, 25 °C | Open record: Pf6PGD (6-phosphogluconate dehydrogenase), nicotinamide adenine dinucleotide phosphate (oxidized) |
| Pf6PGD (6-phosphogluconate dehydrogenase)variant W104L | Plasmodium falciparum | 6-phosphogluconate | 5.2 | 0.0058 | 900 calc. | pH 8, 25 °C | Open record: Pf6PGD (6-phosphogluconate dehydrogenase) variant W104L, 6-phosphogluconate |
| Pf6PGD (6-phosphogluconate dehydrogenase)variant W104L | Plasmodium falciparum | nicotinamide adenine dinucleotide phosphate (oxidized) | 5.7 | 0.0048 | 1.2 × 10³ calc. | pH 8, 25 °C | Open record: Pf6PGD (6-phosphogluconate dehydrogenase) variant W104L, nicotinamide adenine dinucleotide phosphate (oxidized) |