Values CatLog read from this paper

Pyrimethamine-resistant dihydrofolate reductase enzymes of Plasmodium falciparum are not enzymatically compromised in vitro

PMID 17451822doi:10.1016/j.molbiopara.2007.03.009Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 8 records (16 values) from this paper: dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase) from Plasmodium falciparum.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.5.1.3, EC 2.1.1.45

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase)Plasmodium falciparum7,8-dihydrofolate1.240.044428pH 7, 25 °COpen record: dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase), 7,8-dihydrofolate
dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase)Plasmodium falciparumNADPH—0.0232—pH 7, 25 °COpen record: dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase), NADPH
dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase)variant 51I/59R/108NPlasmodium falciparum7,8-dihydrofolate1.230.020959pH 7, 25 °COpen record: dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase) variant 51I/59R/108N, 7,8-dihydrofolate
dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase)variant 51I/59R/108NPlasmodium falciparumNADPH—0.0379—pH 7, 25 °COpen record: dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase) variant 51I/59R/108N, NADPH
dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase)variant 51I/59R/108N/164LPlasmodium falciparum7,8-dihydrofolate1.420.020769pH 7, 25 °COpen record: dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase) variant 51I/59R/108N/164L, 7,8-dihydrofolate
dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase)variant 51I/59R/108N/164LPlasmodium falciparumNADPH—0.0373—pH 7, 25 °COpen record: dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase) variant 51I/59R/108N/164L, NADPH
dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase)variant 51I/59R/108N/213APlasmodium falciparum7,8-dihydrofolate0.680.010266pH 7, 25 °COpen record: dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase) variant 51I/59R/108N/213A, 7,8-dihydrofolate
dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase)variant 51I/59R/108N/213APlasmodium falciparumNADPH—0.0309—pH 7, 25 °COpen record: dihydrofolate reductase (DHFR domain of the bifunctional DHFR-thymidylate synthase) variant 51I/59R/108N/213A, NADPH