Values CatLog read from this paper
Arginine-178 is an essential residue for ITPA function
PMID 37506994doi:10.1016/j.abb.2023.109700Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 5 records (15 values) from this paper: inosine triphosphate pyrophosphatase (ITPA) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| inosine triphosphate pyrophosphatase (ITPA) | Homo sapiens | inosine triphosphate | 4.7 | 0.0117 | 401 | 37 °C | Open record: inosine triphosphate pyrophosphatase (ITPA), inosine triphosphate |
| inosine triphosphate pyrophosphatase (ITPA)variant R178A | Homo sapiens | inosine triphosphate | 0.022 | 0.115 | 0.2 | 37 °C | Open record: inosine triphosphate pyrophosphatase (ITPA) variant R178A, inosine triphosphate |
| inosine triphosphate pyrophosphatase (ITPA)variant R178C | Homo sapiens | inosine triphosphate | 0.038 | 0.0184 | 2.1 | 37 °C | Open record: inosine triphosphate pyrophosphatase (ITPA) variant R178C, inosine triphosphate |
| inosine triphosphate pyrophosphatase (ITPA)variant R178K | Homo sapiens | inosine triphosphate | 3.3 | 0.216 | 15.2 | 37 °C | Open record: inosine triphosphate pyrophosphatase (ITPA) variant R178K, inosine triphosphate |
| inosine triphosphate pyrophosphatase (ITPA)variant R178S | Homo sapiens | inosine triphosphate | 0.072 | 0.116 | 0.62 | 37 °C | Open record: inosine triphosphate pyrophosphatase (ITPA) variant R178S, inosine triphosphate |