Values CatLog read from this paper
Plasmodium falciparum Sir2 is an NAD+-dependent deacetylase and an acetyllysine-dependent and acetyllysine-independent NAD+ glycohydrolase
PMID 18729382doi:10.1021/bi800767tOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (14 values) from this paper: Pf-Sir2 (Plasmodium falciparum Sir2) from Plasmodium falciparum.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 6 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| Pf-Sir2 (Plasmodium falciparum Sir2) | Plasmodium falciparum | ARTKQTAR(K-Ac)STGG(K-Ac)APRKQLAS | 2.5 × 10⁻⁴ | 0.372 | 6.7 × 10⁻⁴ calc. | pH 7.3, 30 °C | Open record: Pf-Sir2 (Plasmodium falciparum Sir2), ARTKQTAR(K-Ac)STGG(K-Ac)APRKQLAS |
| Pf-Sir2 (Plasmodium falciparum Sir2) | Plasmodium falciparum | ERSTEL(K-Ac)TEI(K-Ac)EEEDQPSTS | 9.2 × 10⁻⁴ | 0.085 | 0.011 calc. | pH 7.3, 30 °C | Open record: Pf-Sir2 (Plasmodium falciparum Sir2), ERSTEL(K-Ac)TEI(K-Ac)EEEDQPSTS |
| Pf-Sir2 (Plasmodium falciparum Sir2) | Plasmodium falciparum | nicotinamideH3 peptide | 0.025 | 0.061 | 0.41 calc. | pH 7.5, 30 °C | Open record: Pf-Sir2 (Plasmodium falciparum Sir2), nicotinamide |
| Pf-Sir2 (Plasmodium falciparum Sir2) | Plasmodium falciparum | nicotinamide200 µM acetylated p300 peptide; p300 peptide | 0.064 | 0.08 | 0.80 calc. | pH 7.5, 30 °C | Open record: Pf-Sir2 (Plasmodium falciparum Sir2), nicotinamide |
| Pf-Sir2 (Plasmodium falciparum Sir2) | Plasmodium falciparum | nicotinamide adenine dinucleotide (oxidized form) | — | 0.12 | — | pH 7.3, 30 °C | Open record: Pf-Sir2 (Plasmodium falciparum Sir2), nicotinamide adenine dinucleotide (oxidized form) |
| Pf-Sir2 (Plasmodium falciparum Sir2) | Plasmodium falciparum | nicotinamide adenine dinucleotide (oxidized form) | 0.0012 | — | — | pH 7.3 | Open record: Pf-Sir2 (Plasmodium falciparum Sir2), nicotinamide adenine dinucleotide (oxidized form) |
| Pf-Sir2 (Plasmodium falciparum Sir2) | Plasmodium falciparum | SGRG(K-Ac)GG(K-Ac)GLG(K-Ac)GGA(K-Ac)RHR | 3.5 × 10⁻⁴ | 0.176 | 0.0020 calc. | pH 7.3, 30 °C | Open record: Pf-Sir2 (Plasmodium falciparum Sir2), SGRG(K-Ac)GG(K-Ac)GLG(K-Ac)GGA(K-Ac)RHR |
| Pf-Sir2 (Plasmodium falciparum Sir2) | Plasmodium falciparum | thionicotinamide | 0.006 | 0.495 | 0.012 calc. | pH 7.3, 30 °C | Open record: Pf-Sir2 (Plasmodium falciparum Sir2), thionicotinamide |