Values CatLog read from this paper
Different ways to transport ammonia in human and Mycobacterium tuberculosis NAD+ synthetases
PMID 31911602doi:10.1038/s41467-019-13845-4Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 18 records (34 values) from this paper: NAD+ synthetase (hsNadE), NAD+ synthetase (tbNadE) from Homo sapiens, Mycobacterium tuberculosis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| NAD+ synthetase (hsNadE) | Homo sapiens | adenosine 5'-triphosphateglutamine-dependent reaction; saturating L-glutamine 100 mM | 3.79 | 0.17 | 22 | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), adenosine 5'-triphosphate |
| NAD+ synthetase (hsNadE) | Homo sapiens | adenosine 5'-triphosphateammonia-dependent reaction (NH4Cl as ammonia source) | 18.5 | 0.22 | 84 | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), adenosine 5'-triphosphate |
| NAD+ synthetase (hsNadE) | Homo sapiens | ammonia | 20 | 42 | 0.49 | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), ammonia |
| NAD+ synthetase (hsNadE) | Homo sapiens | L-glutamineglutamine-dependent reaction; saturating NaAD+ 5 mM; Table 1 | 3.72 | 8.3 | 0.45 | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), L-glutamine |
| NAD+ synthetase (hsNadE) | Homo sapiens | L-glutamineglutamine-dependent reaction; saturating NaAD+ 5 mM; Table 1 | 5.6 | 11.6 | 0.48 | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), L-glutamine |
| NAD+ synthetase (hsNadE) | Homo sapiens | L-glutamineglutamine-dependent reaction; no NaAD+ or ATP; Table 1 | 0.18 | 34 | 0.005 | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), L-glutamine |
| NAD+ synthetase (hsNadE) | Homo sapiens | L-glutamineeffectors: NaAD+ (5 mM); Table 2 | 0.316 | — | — | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), L-glutamine |
| NAD+ synthetase (hsNadE) | Homo sapiens | L-glutamineeffectors: NAD+ (4 mM); Table 2 | 0.214 | — | — | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), L-glutamine |
| NAD+ synthetase (hsNadE) | Homo sapiens | L-glutamineeffectors: ATP/Mg2+ (ATP 4 mM); Table 2 | 0.091 | — | — | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), L-glutamine |
| NAD+ synthetase (hsNadE) | Homo sapiens | L-glutamineeffectors: PPi/Mg2+ (PPi 2.5 mM); Table 2 | 0.185 | — | — | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), L-glutamine |
| NAD+ synthetase (hsNadE) | Homo sapiens | L-glutamineeffectors: NAD+ (4 mM); ATP/Mg2+ (ATP 4 mM); Table 2 | 0.113 | — | — | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), L-glutamine |
| NAD+ synthetase (hsNadE) | Homo sapiens | L-glutamineeffectors: NaAD+ (5 mM); AMP/Mg2+ (AMP 5 mM); Table 2 | 0.375 | — | — | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), L-glutamine |
| NAD+ synthetase (hsNadE) | Homo sapiens | L-glutamineeffectors: NaAD+ (5 mM); AMP (5 mM); PPi/Mg2+ (PPi 2.5 mM) | 2.2 | — | — | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), L-glutamine |
| NAD+ synthetase (hsNadE) | Homo sapiens | nicotinic acid adenine dinucleotideglutamine-dependent reaction; saturating L-glutamine 100 mM | 3.2 | 0.26 | 12 | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), nicotinic acid adenine dinucleotide |
| NAD+ synthetase (hsNadE) | Homo sapiens | nicotinic acid adenine dinucleotideammonia-dependent reaction (NH4Cl as ammonia source) | 23.4 | 0.52 | 45 | pH 8, 37 °C | Open record: NAD+ synthetase (hsNadE), nicotinic acid adenine dinucleotide |
| NAD+ synthetase (tbNadE) | Mycobacterium tuberculosis | L-glutamineeffectors: no effectors | 0.0038 | — | — | Open record: NAD+ synthetase (tbNadE), L-glutamine | |
| NAD+ synthetase (tbNadE) | Mycobacterium tuberculosis | L-glutamineeffectors: SFI (5 mM) | 0.0021 | — | — | Open record: NAD+ synthetase (tbNadE), L-glutamine | |
| NAD+ synthetase (tbNadE) | Mycobacterium tuberculosis | L-glutamineeffectors: SFI (5 mM); PPi/Mg2+ (PPi 2.5 mM) | 0.061 | — | — | Open record: NAD+ synthetase (tbNadE), L-glutamine |