Values CatLog read from this paper
Altering the allosteric pathway in IGPS suppresses millisecond motions and catalytic activity
PMID 28396388doi:10.1073/pnas.1700448114Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 10 records (30 values) from this paper: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit from Thermotoga maritima.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutamine | 3.62 | 1.74 | 2.08 | pH 8, 30 °C | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.00165 | 3.57 | 4.6 × 10⁻⁴ | pH 8, 30 °C | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF D98A | Thermotoga maritima | L-glutamine | 0.18 | 3.11 | 0.0579 | pH 8, 30 °C | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF D98A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF D98A | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.00311 | 2.88 | 0.00107 | pH 8, 30 °C | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF D98A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF K19A | Thermotoga maritima | L-glutamine | 0.57 | 3.41 | 0.166 | pH 8, 30 °C | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF K19A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF K19A | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.0054 | 3 | 0.0018 | pH 8, 30 °C | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF K19A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF V12A | Thermotoga maritima | L-glutamine | 1.88 | 1.4 | 1.34 | pH 8, 30 °C | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF V12A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF V12A | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.00173 | 4.12 | 4.2 × 10⁻⁴ | pH 8, 30 °C | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF V12A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF V48A | Thermotoga maritima | L-glutamine | 0.24 | 1.99 | 0.122 | pH 8, 30 °C | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF V48A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF V48A | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.00328 | 3.76 | 8.72 × 10⁻⁴ | pH 8, 30 °C | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF V48A, L-glutamine |