EC 4.3.2.10: imidazole glycerol-phosphate synthase
LyasesOpen in Browse
CatLog read 146 records for EC 4.3.2.10 from 7 papers, for 2 organisms. Names in these papers: imidazole glycerol phosphate synthase (IGP synthase), imidazole glycerol phosphate synthase, imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH, imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) and 5 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 24 records for EC 4.3.2.10 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.3.2.10 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Boosting Reversible Photocontrol of a Photoxenase by an Engineered Conformational Shift | Thermotoga maritima | 48 |
| Substrate-induced changes in the ammonia channel for imidazole glycerol phosphate synthase | Saccharomyces cerevisiae | 46 |
| Reaction coupling through interdomain contacts in imidazole glycerol phosphate synthase | Saccharomyces cerevisiae | 25 |
| Altering the allosteric pathway in IGPS suppresses millisecond motions and catalytic activity | Thermotoga maritima | 10 |
| Glutamine Hydrolysis by Imidazole Glycerol Phosphate Synthase Displays Temperature Dependent Allosteric Activation | Thermotoga maritima | 10 |
| Imidazole glycerol phosphate synthase from Thermotoga maritima. Quaternary structure, steady-state kinetics, and reaction mechanism of the bienzyme complex | Thermotoga maritima | 6 |
| A sugar isomerization reaction established on various (βα)₈-barrel scaffolds is based on substrate-assisted catalysis | Thermotoga maritima | 1 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| HisFvariant D130V/D176V | Thermotoga maritima | phosphoribosylanthranilate | 0.00122 | 0.018 | 0.069 | pH 7.5, 25 °C | PMID 23109729 | Open record: HisF variant D130V/D176V, phosphoribosylanthranilate |
| imidazole glycerol phosphate synthasevariant D359A | Saccharomyces cerevisiae | L-glutamineassay per ref 16; 1 h incubation | 7.8 × 10⁻⁴ | 1.4 | 5.5 × 10⁻⁴ | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant D359A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant D359A | Saccharomyces cerevisiae | L-glutaminePRFAR fixed at 100 µM; assay per ref 16 | 0.004 | 4.2 | 0.001 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant D359A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant D359A | Saccharomyces cerevisiae | L-glutaminereaction A (Figure 1); PRFAR fixed at 100 µM | 0.0059 | 14 | 4.2 × 10⁻⁴ | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant D359A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant D359A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 2.9 × 10⁻⁴ | 0.0055 | 0.52 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant D359A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthasevariant D359A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.39 | 0.109 | 3.6 | pH 7 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant D359A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthasevariant K196A | Saccharomyces cerevisiae | L-glutamineassay per ref 16; 1 h incubation | 0.021 | 1.72 | 0.0127 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant K196A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant K196A | Saccharomyces cerevisiae | L-glutaminePRFAR fixed at 100 µM; assay per ref 16 | 9.8 | 0.44 | 25 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant K196A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant K196A | Saccharomyces cerevisiae | L-glutaminereaction A (Figure 1); PRFAR fixed at 100 µM | 0.6 | 0.49 | 1.2 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant K196A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant K196A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.74 | 2.7 × 10⁻⁴ | 2.8 × 10³ | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant K196A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthasevariant K196A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.46 | 0.034 | 14 | pH 7 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant K196A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthasevariant K196A/D359A | Saccharomyces cerevisiae | L-glutamineassay per ref 16; 1 h incubation | 0.003 | 1.6 | 0.0022 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant K196A/D359A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant K196A/D359A | Saccharomyces cerevisiae | L-glutaminePRFAR fixed at 100 µM; assay per ref 16 | 0.209 | 0.5 | 0.39 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant K196A/D359A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant K196A/D359A | Saccharomyces cerevisiae | L-glutaminereaction A (Figure 1); PRFAR fixed at 100 µM | 0.007 | 2.3 | 0.0032 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant K196A/D359A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant K196A/D359A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.007 | 0.0141 | 0.51 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant K196A/D359A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthasevariant K196A/D359A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.11 | 0.026 | 3.8 | pH 7 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant K196A/D359A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthasevariant N13A | Saccharomyces cerevisiae | L-glutamineassay per ref 16; 1 h incubation | 0.0014 | 6.2 | 2.3 × 10⁻⁴ | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant N13A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant N13A | Saccharomyces cerevisiae | L-glutaminePRFAR fixed at 100 µM; assay per ref 16 | 0.1 | 5 | 0.023 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant N13A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant N13A | Saccharomyces cerevisiae | L-glutaminereaction A (Figure 1); PRFAR fixed at 100 µM | 0.019 | 4.8 | 0.004 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant N13A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant N13A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.0112 | 0.0013 | 9 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant N13A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthasevariant N13A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.35 | 0.071 | 4.9 | pH 7 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant N13A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthasevariant Q397A | Saccharomyces cerevisiae | L-glutamineassay per ref 16; 1 h incubation | 0.0018 | 8.3 | 2.2 × 10⁻⁴ | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant Q397A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant Q397A | Saccharomyces cerevisiae | L-glutaminePRFAR fixed at 100 µM; assay per ref 16 | 1.1 | 2.5 | 0.45 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant Q397A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant Q397A | Saccharomyces cerevisiae | L-glutaminereaction A (Figure 1); PRFAR fixed at 100 µM | 1.4 | 7 | 0.21 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant Q397A, L-glutamine | |
| imidazole glycerol phosphate synthasevariant Q397A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.56 | 0.0036 | 160 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant Q397A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthasevariant Q397A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.38 | 0.03 | 12 | pH 7 | PMID 16142895 | Open record: imidazole glycerol phosphate synthase variant Q397A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF I73P (hAzoF_fI73P) | Thermotoga maritima | L-glutaminethermal equilibrium (TEQ); no irradiation (E-enriched AzoF) | — | 2.21 | 0.0165 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF I73P (hAzoF_fI73P), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF I73P (hAzoF_fI73P) | Thermotoga maritima | L-glutaminephotostationary state PSS365 | — | 0.59 | 1.669 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF I73P (hAzoF_fI73P), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF I73P (hAzoF_fI73P) | Thermotoga maritima | L-glutaminephotostationary state PSS420 | — | 0.45 | 0.7864 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF I73P (hAzoF_fI73P), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF I73P/I75K (hAzoF_fI73P-fI75K) | Thermotoga maritima | L-glutaminethermal equilibrium (TEQ); no irradiation (E-enriched AzoF) | — | 0.88 | 0.0066 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF I73P/I75K (hAzoF_fI73P-fI75K), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF I73P/I75K (hAzoF_fI73P-fI75K) | Thermotoga maritima | L-glutaminephotostationary state PSS365 | — | 1.06 | 0.4678 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF I73P/I75K (hAzoF_fI73P-fI75K), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF I73P/I75K (hAzoF_fI73P-fI75K) | Thermotoga maritima | L-glutaminephotostationary state PSS420 | — | 0.89 | 0.1933 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF I73P/I75K (hAzoF_fI73P-fI75K), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF I75K (hAzoF_fI75K) | Thermotoga maritima | L-glutaminethermal equilibrium (TEQ); no irradiation (E-enriched AzoF) | — | 0.58 | 0.0289 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF I75K (hAzoF_fI75K), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF I75K (hAzoF_fI75K) | Thermotoga maritima | L-glutaminephotostationary state PSS365 | — | 1.16 | 0.69 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF I75K (hAzoF_fI75K), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF I75K (hAzoF_fI75K) | Thermotoga maritima | L-glutaminephotostationary state PSS420 | — | 0.47 | 0.5349 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF I75K (hAzoF_fI75K), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF L2D (hAzoF_fL2D) | Thermotoga maritima | L-glutaminethermal equilibrium (TEQ); no irradiation (E-enriched AzoF) | — | 1.25 | 0.0112 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF L2D (hAzoF_fL2D), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF L2D (hAzoF_fL2D) | Thermotoga maritima | L-glutaminephotostationary state PSS365 | — | 0.96 | 0.6694 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF L2D (hAzoF_fL2D), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF L2D (hAzoF_fL2D) | Thermotoga maritima | L-glutaminephotostationary state PSS420 | — | 0.45 | 0.5479 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF L2D (hAzoF_fL2D), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF L2D/I73P (hAzoF_fL2D-fI73P) | Thermotoga maritima | L-glutaminethermal equilibrium (TEQ); no irradiation (E-enriched AzoF) | — | 2.04 | 0.003 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF L2D/I73P (hAzoF_fL2D-fI73P), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF L2D/I73P (hAzoF_fL2D-fI73P) | Thermotoga maritima | L-glutaminephotostationary state PSS365 | — | 0.98 | 0.1659 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF L2D/I73P (hAzoF_fL2D-fI73P), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF L2D/I73P (hAzoF_fL2D-fI73P) | Thermotoga maritima | L-glutaminephotostationary state PSS420 | — | 1.39 | 0.0673 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF L2D/I73P (hAzoF_fL2D-fI73P), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF L2D/I73P/I75K (hAzoF_fL2D-fI73P-fI75K) | Thermotoga maritima | L-glutaminethermal equilibrium (TEQ); no irradiation (E-enriched AzoF) | — | 1.74 | 5 × 10⁻⁴ | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF L2D/I73P/I75K (hAzoF_fL2D-fI73P-fI75K), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF L2D/I73P/I75K (hAzoF_fL2D-fI73P-fI75K) | Thermotoga maritima | L-glutaminephotostationary state PSS365 | — | 1.19 | 0.0268 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF L2D/I73P/I75K (hAzoF_fL2D-fI73P-fI75K), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF L2D/I73P/I75K (hAzoF_fL2D-fI73P-fI75K) | Thermotoga maritima | L-glutaminephotostationary state PSS420 | — | 1.39 | 0.0116 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF L2D/I73P/I75K (hAzoF_fL2D-fI73P-fI75K), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF L2D/I75K (hAzoF_fL2D-fI75K) | Thermotoga maritima | L-glutaminethermal equilibrium (TEQ); no irradiation (E-enriched AzoF) | — | 2.44 | 0.0029 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF L2D/I75K (hAzoF_fL2D-fI75K), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF L2D/I75K (hAzoF_fL2D-fI75K) | Thermotoga maritima | L-glutaminephotostationary state PSS365 | — | 1.62 | 0.0817 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF L2D/I75K (hAzoF_fL2D-fI75K), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF L2D/I75K (hAzoF_fL2D-fI75K) | Thermotoga maritima | L-glutaminephotostationary state PSS420 | — | 1.57 | 0.0377 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF L2D/I75K (hAzoF_fL2D-fI75K), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF wild type (hAzoF_HisF) | Thermotoga maritima | L-glutaminethermal equilibrium (TEQ); no irradiation (E-enriched AzoF) | — | 0.71 | 0.1493 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF wild type (hAzoF_HisF), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF wild type (hAzoF_HisF) | Thermotoga maritima | L-glutaminephotostationary state PSS365 | — | 0.18 | 8.544 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF wild type (hAzoF_HisF), L-glutamine |
| imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisHvariant HisH W123AzoF; HisF wild type (hAzoF_HisF) | Thermotoga maritima | L-glutaminephotostationary state PSS420 | — | 0.13 | 5.958 | pH 7, 28 °C | PMID 41255148 | Open record: imidazole glycerol phosphate synthase (HisH_HisF); glutaminase subunit HisH variant HisH W123AzoF; HisF wild type (hAzoF_HisF), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamine | 6.9 | 1.8 | 3.8 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamine1 h incubation; Table 5 | 0.0055 | 4.7 | 0.00118 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation; Table 5 | 6.8 | 1.2 | 5.8 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamineno PRFAR; effector concentration not stated; Table 3 | 2.15 | 0.9 | 2.3 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamineno PRFAR; effector concentration not stated; Table 3 | 0.14 | 1.1 | 0.13 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamineno PRFAR; effector concentration not stated; Table 3 | 0.06 | 1.8 | 0.031 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamineno PRFAR; effector concentration not stated; Table 3 | 0.04 | 0.5 | 0.084 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamineno PRFAR; effector concentration not stated; Table 3 | 0.12 | 0.3 | 0.38 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamineno PRFAR; effector concentration not stated; Table 3 | 0.14 | 1.8 | 0.078 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 5.4 | 0.005 | 1.2 × 10³ | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase), N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.845 | 0.055 | 15 | pH 7 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase), N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258A | Saccharomyces cerevisiae | L-glutamine | 0.025 | 6.5 | 0.0036 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258A, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258A | Saccharomyces cerevisiae | L-glutamine1 h incubation | 0.0081 | 2.7 | 0.0031 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258A, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258A | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 0.172 | 1.2 | 0.14 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258A, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.045 | 0.098 | 0.46 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.0054 | 0.139 | 0.039 | pH 7 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258R | Saccharomyces cerevisiae | L-glutamine | 0.159 | 1.9 | 0.084 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258R, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258R | Saccharomyces cerevisiae | L-glutamine1 h incubation | 0.0075 | 3.3 | 0.0023 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258R, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258R | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 0.164 | 0.64 | 0.26 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258R, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258R | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.126 | 0.002 | 60 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258R, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258R | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.005 | 0.046 | 0.12 | pH 7 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258R, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360A | Saccharomyces cerevisiae | L-glutamine | 0.49 | 1.96 | 0.247 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360A, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360A | Saccharomyces cerevisiae | L-glutamine1 h incubation | 0.002 | 4.4 | 4.5 × 10⁻⁴ | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360A, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360A | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 7.8 | 1.9 | 4.1 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360A, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.24 | 0.0018 | 130 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.7 | 0.065 | 11 | pH 7 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360R | Saccharomyces cerevisiae | L-glutamine | 1.13 | 1.9 | 0.59 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360R, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360R | Saccharomyces cerevisiae | L-glutamine1 h incubation | 0.00131 | 1.7 | 7 × 10⁻⁴ | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360R, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360R | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 0.61 | 1.24 | 0.49 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360R, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360R | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.29 | 0.0023 | 110 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360R, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360R | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.31 | 0.072 | 4.3 | pH 7 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360R, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239A | Saccharomyces cerevisiae | L-glutamine | 0.0069 | 6.5 | 0.0011 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239A, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239A | Saccharomyces cerevisiae | L-glutamine1 h incubation | 0.0014 | 2.3 | 6 × 10⁻⁴ | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239A, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239A | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 0.18 | 0.35 | 0.52 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239A, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.0043 | 0.003 | 1.4 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.15 | 0.053 | 2.8 | pH 7 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239H | Saccharomyces cerevisiae | L-glutamine | 0.006 | 2.1 | 0.0028 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239H, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239H | Saccharomyces cerevisiae | L-glutamine1 h incubation | 0.0016 | 0.8 | 0.0021 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239H, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239H | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 0.24 | 1.62 | 0.15 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239H, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239H | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.039 | 0.0079 | 0.5 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239H, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239H | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.21 | 0.075 | 2.9 | pH 7 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239H, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239K | Saccharomyces cerevisiae | L-glutamine | 0.009 | 1.3 | 0.007 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239K, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239K | Saccharomyces cerevisiae | L-glutamine1 h incubation | 5 × 10⁻⁴ | 0.6 | 8 × 10⁻⁴ | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239K, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239K | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 0.366 | 1.04 | 0.35 | pH 7, 30 °C | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239K, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239K | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.0087 | 0.0016 | 5.5 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239K, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239K | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.3 | 0.08 | 3.8 | pH 7 | PMID 12795596 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239K, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutamine | 3.62 | 1.74 | 2.08 | pH 8, 30 °C | PMID 28396388 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.00165 | 3.57 | 4.6 × 10⁻⁴ | pH 8, 30 °C | PMID 28396388 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutamine | 4.09 | 1.3 | 3.15 | pH 8, 30 °C | PMID 29468164 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.00372 | 4.91 | 7.58 × 10⁻⁴ | pH 8, 30 °C | PMID 29468164 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutamine | 4.37 | 1.35 | 3.24 | pH 8, 40 °C | PMID 29468164 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.0571 | 4.71 | 0.0121 | pH 8, 40 °C | PMID 29468164 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutamine | 4.89 | 1.64 | 2.98 | pH 8, 50 °C | PMID 29468164 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.139 | 3.8 | 0.0365 | pH 8, 50 °C | PMID 29468164 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutamine | 5.5 | 1.36 | 4.04 | pH 8, 60 °C | PMID 29468164 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.212 | 3.89 | 0.0544 | pH 8, 60 °C | PMID 29468164 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutamine | 5.92 | 1.32 | 4.48 | pH 8, 70 °C | PMID 29468164 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.204 | 2.96 | 0.0688 | pH 8, 70 °C | PMID 29468164 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF D98A | Thermotoga maritima | L-glutamine | 0.18 | 3.11 | 0.0579 | pH 8, 30 °C | PMID 28396388 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF D98A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF D98A | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.00311 | 2.88 | 0.00107 | pH 8, 30 °C | PMID 28396388 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF D98A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF K19A | Thermotoga maritima | L-glutamine | 0.57 | 3.41 | 0.166 | pH 8, 30 °C | PMID 28396388 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF K19A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF K19A | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.0054 | 3 | 0.0018 | pH 8, 30 °C | PMID 28396388 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF K19A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF V12A | Thermotoga maritima | L-glutamine | 1.88 | 1.4 | 1.34 | pH 8, 30 °C | PMID 28396388 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF V12A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF V12A | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.00173 | 4.12 | 4.2 × 10⁻⁴ | pH 8, 30 °C | PMID 28396388 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF V12A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF V48A | Thermotoga maritima | L-glutamine | 0.24 | 1.99 | 0.122 | pH 8, 30 °C | PMID 28396388 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF V48A, L-glutamine |
| imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunitvariant HisF V48A | Thermotoga maritima | L-glutaminebasal: no PRFAR | 0.00328 | 3.76 | 8.72 × 10⁻⁴ | pH 8, 30 °C | PMID 28396388 | Open record: imidazole glycerol phosphate synthase (IGPS; HisH/HisF complex), glutaminase activity of the HisH subunit variant HisF V48A, L-glutamine |
| imidazole glycerol phosphate synthase (tHisH-tHisF complex) | Thermotoga maritima | L-glutamine | 0.4 | 0.32 | 1.4 | pH 8, 25 °C | PMID 11264293 | Open record: imidazole glycerol phosphate synthase (tHisH-tHisF complex), L-glutamine |
| imidazole glycerol phosphate synthase (tHisH-tHisF complex) | Thermotoga maritima | N'-((5'-phosphoribulosyl)formimino)-5-aminoimidazole-4-carboxamide-ribonucleotide | 0.8 | 0.0015 | 600 | pH 8, 25 °C | PMID 11264293 | Open record: imidazole glycerol phosphate synthase (tHisH-tHisF complex), N'-((5'-phosphoribulosyl)formimino)-5-aminoimidazole-4-carboxamide-ribonucleotide |
| imidazole glycerol phosphate synthase glutaminase subunit HisH (tHisH, in tHisH-tHisF complex) | Thermotoga maritima | L-glutamineImGP | 0.1 | 0.5 | 0.2 | pH 8, 25 °C | PMID 11264293 | Open record: imidazole glycerol phosphate synthase glutaminase subunit HisH (tHisH, in tHisH-tHisF complex), L-glutamine |
| imidazole glycerol phosphate synthase glutaminase subunit HisH (tHisH, in tHisH-tHisF complex) | Thermotoga maritima | L-glutamineProFAR | 0.1 | — | — | pH 8, 25 °C | PMID 11264293 | Open record: imidazole glycerol phosphate synthase glutaminase subunit HisH (tHisH, in tHisH-tHisF complex), L-glutamine |
| imidazole glycerol phosphate synthase subunit HisF (tHisF, isolated) | Thermotoga maritima | ammonia | 2 | 2.2 | 0.9 | pH 8.5, 25 °C | PMID 11264293 | Open record: imidazole glycerol phosphate synthase subunit HisF (tHisF, isolated), ammonia |
| imidazole glycerol phosphate synthase subunit HisF (tHisF, isolated) | Thermotoga maritima | N'-((5'-phosphoribulosyl)formimino)-5-aminoimidazole-4-carboxamide-ribonucleotide | 2.2 | 0.0017 | 1.3 × 10³ | pH 8.5, 25 °C | PMID 11264293 | Open record: imidazole glycerol phosphate synthase subunit HisF (tHisF, isolated), N'-((5'-phosphoribulosyl)formimino)-5-aminoimidazole-4-carboxamide-ribonucleotide |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF I73P | Thermotoga maritima | glutamineAzoF in its thermal equilibrium (TEQ) | 0.037 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF I73P, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF I73P | Thermotoga maritima | glutamineAzoF in PSS^365 after 2 s per well 365 nm irradiation | 0.982 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF I73P, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF I73P | Thermotoga maritima | glutamineapplied after addition to the reaction mixture | 0.357 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF I73P, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF I73P/I75K | Thermotoga maritima | glutamineAzoF in its thermal equilibrium (TEQ) | 0.005 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF I73P/I75K, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF I73P/I75K | Thermotoga maritima | glutamineAzoF in PSS^365 after 2 s per well 365 nm irradiation | 0.495 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF I73P/I75K, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF I73P/I75K | Thermotoga maritima | glutamineapplied after addition to the reaction mixture | 0.172 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF I73P/I75K, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF I75K | Thermotoga maritima | glutamineAzoF in its thermal equilibrium (TEQ) | 0.017 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF I75K, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF I75K | Thermotoga maritima | glutamineAzoF in PSS^365 after 2 s per well 365 nm irradiation | 0.802 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF I75K, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF I75K | Thermotoga maritima | glutamineapplied after addition to the reaction mixture | 0.253 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF I75K, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF L2D | Thermotoga maritima | glutamineAzoF in its thermal equilibrium (TEQ) | 0.013 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF L2D, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF L2D | Thermotoga maritima | glutamineAzoF in PSS^365 after 2 s per well 365 nm irradiation | 0.64 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF L2D, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF L2D | Thermotoga maritima | glutamineapplied after addition to the reaction mixture | 0.25 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF L2D, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF L2D/I73P | Thermotoga maritima | glutamineAzoF in its thermal equilibrium (TEQ) | 0.0067 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF L2D/I73P, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF L2D/I73P | Thermotoga maritima | glutamineAzoF in PSS^365 after 2 s per well 365 nm irradiation | 0.162 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF L2D/I73P, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF L2D/I73P | Thermotoga maritima | glutamineapplied after addition to the reaction mixture | 0.093 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF L2D/I73P, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF L2D/I73P/I75K | Thermotoga maritima | glutamineAzoF in its thermal equilibrium (TEQ) | 0.0017 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF L2D/I73P/I75K, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF L2D/I73P/I75K | Thermotoga maritima | glutamineAzoF in PSS^365 after 2 s per well 365 nm irradiation | 0.032 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF L2D/I73P/I75K, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF L2D/I73P/I75K | Thermotoga maritima | glutamineapplied after addition to the reaction mixture | 0.017 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF L2D/I73P/I75K, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF L2D/I75K | Thermotoga maritima | glutamineAzoF in its thermal equilibrium (TEQ) | 0.0067 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF L2D/I75K, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF L2D/I75K | Thermotoga maritima | glutamineAzoF in PSS^365 after 2 s per well 365 nm irradiation | 0.132 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF L2D/I75K, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF L2D/I75K | Thermotoga maritima | glutamineapplied after addition to the reaction mixture | 0.058 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF L2D/I75K, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF wild type | Thermotoga maritima | glutamineAzoF in its thermal equilibrium (TEQ) | 0.107 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF wild type, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF wild type | Thermotoga maritima | glutamineAzoF in PSS^365 after 2 s per well 365 nm irradiation | 1.573 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF wild type, glutamine | |
| imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF)variant HisH W123AzoF (hAzoF); HisF wild type | Thermotoga maritima | glutamineapplied after addition to the reaction mixture | 0.787 | — | — | PMID 41255148 | Open record: imidazole glycerol phosphate synthase, glutaminase subunit HisH (photoxenase hAzoF in complex with HisF) variant HisH W123AzoF (hAzoF); HisF wild type, glutamine |