Values CatLog read from this paper

Reaction coupling through interdomain contacts in imidazole glycerol phosphate synthase

PMID 16142895doi:10.1021/bi050706bOpen in Browse

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CatLog read 25 records (75 values) from this paper: imidazole glycerol phosphate synthase from Saccharomyces cerevisiae.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.5.1.2, EC 4.3.2.10

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
imidazole glycerol phosphate synthasevariant D359A	Saccharomyces cerevisiae	L-glutamineassay per ref 16; 1 h incubation	7.8 × 10⁻⁴	1.4	5.5 × 10⁻⁴		Open record: imidazole glycerol phosphate synthase variant D359A, L-glutamine
imidazole glycerol phosphate synthasevariant D359A	Saccharomyces cerevisiae	L-glutaminePRFAR fixed at 100 µM; assay per ref 16	0.004	4.2	0.001		Open record: imidazole glycerol phosphate synthase variant D359A, L-glutamine
imidazole glycerol phosphate synthasevariant D359A	Saccharomyces cerevisiae	L-glutaminereaction A (Figure 1); PRFAR fixed at 100 µM	0.0059	14	4.2 × 10⁻⁴		Open record: imidazole glycerol phosphate synthase variant D359A, L-glutamine
imidazole glycerol phosphate synthasevariant D359A	Saccharomyces cerevisiae	N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide	2.9 × 10⁻⁴	0.0055	0.52		Open record: imidazole glycerol phosphate synthase variant D359A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide
imidazole glycerol phosphate synthasevariant D359A	Saccharomyces cerevisiae	N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide	0.39	0.109	3.6	pH 7	Open record: imidazole glycerol phosphate synthase variant D359A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide
imidazole glycerol phosphate synthasevariant K196A	Saccharomyces cerevisiae	L-glutamineassay per ref 16; 1 h incubation	0.021	1.72	0.0127		Open record: imidazole glycerol phosphate synthase variant K196A, L-glutamine
imidazole glycerol phosphate synthasevariant K196A	Saccharomyces cerevisiae	L-glutaminePRFAR fixed at 100 µM; assay per ref 16	9.8	0.44	25		Open record: imidazole glycerol phosphate synthase variant K196A, L-glutamine
imidazole glycerol phosphate synthasevariant K196A	Saccharomyces cerevisiae	L-glutaminereaction A (Figure 1); PRFAR fixed at 100 µM	0.6	0.49	1.2		Open record: imidazole glycerol phosphate synthase variant K196A, L-glutamine
imidazole glycerol phosphate synthasevariant K196A	Saccharomyces cerevisiae	N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide	0.74	2.7 × 10⁻⁴	2.8 × 10³		Open record: imidazole glycerol phosphate synthase variant K196A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide
imidazole glycerol phosphate synthasevariant K196A	Saccharomyces cerevisiae	N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide	0.46	0.034	14	pH 7	Open record: imidazole glycerol phosphate synthase variant K196A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide
imidazole glycerol phosphate synthasevariant K196A/D359A	Saccharomyces cerevisiae	L-glutamineassay per ref 16; 1 h incubation	0.003	1.6	0.0022		Open record: imidazole glycerol phosphate synthase variant K196A/D359A, L-glutamine
imidazole glycerol phosphate synthasevariant K196A/D359A	Saccharomyces cerevisiae	L-glutaminePRFAR fixed at 100 µM; assay per ref 16	0.209	0.5	0.39		Open record: imidazole glycerol phosphate synthase variant K196A/D359A, L-glutamine
imidazole glycerol phosphate synthasevariant K196A/D359A	Saccharomyces cerevisiae	L-glutaminereaction A (Figure 1); PRFAR fixed at 100 µM	0.007	2.3	0.0032		Open record: imidazole glycerol phosphate synthase variant K196A/D359A, L-glutamine
imidazole glycerol phosphate synthasevariant K196A/D359A	Saccharomyces cerevisiae	N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide	0.007	0.0141	0.51		Open record: imidazole glycerol phosphate synthase variant K196A/D359A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide
imidazole glycerol phosphate synthasevariant K196A/D359A	Saccharomyces cerevisiae	N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide	0.11	0.026	3.8	pH 7	Open record: imidazole glycerol phosphate synthase variant K196A/D359A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide
imidazole glycerol phosphate synthasevariant N13A	Saccharomyces cerevisiae	L-glutamineassay per ref 16; 1 h incubation	0.0014	6.2	2.3 × 10⁻⁴		Open record: imidazole glycerol phosphate synthase variant N13A, L-glutamine
imidazole glycerol phosphate synthasevariant N13A	Saccharomyces cerevisiae	L-glutaminePRFAR fixed at 100 µM; assay per ref 16	0.1	5	0.023		Open record: imidazole glycerol phosphate synthase variant N13A, L-glutamine
imidazole glycerol phosphate synthasevariant N13A	Saccharomyces cerevisiae	L-glutaminereaction A (Figure 1); PRFAR fixed at 100 µM	0.019	4.8	0.004		Open record: imidazole glycerol phosphate synthase variant N13A, L-glutamine
imidazole glycerol phosphate synthasevariant N13A	Saccharomyces cerevisiae	N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide	0.0112	0.0013	9		Open record: imidazole glycerol phosphate synthase variant N13A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide
imidazole glycerol phosphate synthasevariant N13A	Saccharomyces cerevisiae	N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide	0.35	0.071	4.9	pH 7	Open record: imidazole glycerol phosphate synthase variant N13A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide
imidazole glycerol phosphate synthasevariant Q397A	Saccharomyces cerevisiae	L-glutamineassay per ref 16; 1 h incubation	0.0018	8.3	2.2 × 10⁻⁴		Open record: imidazole glycerol phosphate synthase variant Q397A, L-glutamine
imidazole glycerol phosphate synthasevariant Q397A	Saccharomyces cerevisiae	L-glutaminePRFAR fixed at 100 µM; assay per ref 16	1.1	2.5	0.45		Open record: imidazole glycerol phosphate synthase variant Q397A, L-glutamine
imidazole glycerol phosphate synthasevariant Q397A	Saccharomyces cerevisiae	L-glutaminereaction A (Figure 1); PRFAR fixed at 100 µM	1.4	7	0.21		Open record: imidazole glycerol phosphate synthase variant Q397A, L-glutamine
imidazole glycerol phosphate synthasevariant Q397A	Saccharomyces cerevisiae	N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide	0.56	0.0036	160		Open record: imidazole glycerol phosphate synthase variant Q397A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide
imidazole glycerol phosphate synthasevariant Q397A	Saccharomyces cerevisiae	N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide	0.38	0.03	12	pH 7	Open record: imidazole glycerol phosphate synthase variant Q397A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide