Values CatLog read from this paper
Substrate-induced changes in the ammonia channel for imidazole glycerol phosphate synthase
PMID 12795596doi:10.1021/bi034314lOpen in Browse
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CatLog read 46 records (138 values) from this paper: imidazole glycerol phosphate synthase (IGP synthase) from Saccharomyces cerevisiae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamine | 6.9 | 1.8 | 3.8 | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamine1 h incubation; Table 5 | 0.0055 | 4.7 | 0.00118 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation; Table 5 | 6.8 | 1.2 | 5.8 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamineno PRFAR; effector concentration not stated; Table 3 | 2.15 | 0.9 | 2.3 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamineno PRFAR; effector concentration not stated; Table 3 | 0.14 | 1.1 | 0.13 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamineno PRFAR; effector concentration not stated; Table 3 | 0.06 | 1.8 | 0.031 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamineno PRFAR; effector concentration not stated; Table 3 | 0.04 | 0.5 | 0.084 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamineno PRFAR; effector concentration not stated; Table 3 | 0.12 | 0.3 | 0.38 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | L-glutamineno PRFAR; effector concentration not stated; Table 3 | 0.14 | 1.8 | 0.078 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase), L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 5.4 | 0.005 | 1.2 × 10³ | Open record: imidazole glycerol phosphate synthase (IGP synthase), N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase) | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.845 | 0.055 | 15 | pH 7 | Open record: imidazole glycerol phosphate synthase (IGP synthase), N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258A | Saccharomyces cerevisiae | L-glutamine | 0.025 | 6.5 | 0.0036 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258A, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258A | Saccharomyces cerevisiae | L-glutamine1 h incubation | 0.0081 | 2.7 | 0.0031 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258A, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258A | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 0.172 | 1.2 | 0.14 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258A, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.045 | 0.098 | 0.46 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.0054 | 0.139 | 0.039 | pH 7 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258R | Saccharomyces cerevisiae | L-glutamine | 0.159 | 1.9 | 0.084 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258R, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258R | Saccharomyces cerevisiae | L-glutamine1 h incubation | 0.0075 | 3.3 | 0.0023 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258R, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258R | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 0.164 | 0.64 | 0.26 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258R, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258R | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.126 | 0.002 | 60 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258R, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K258R | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.005 | 0.046 | 0.12 | pH 7 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K258R, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360A | Saccharomyces cerevisiae | L-glutamine | 0.49 | 1.96 | 0.247 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360A, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360A | Saccharomyces cerevisiae | L-glutamine1 h incubation | 0.002 | 4.4 | 4.5 × 10⁻⁴ | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360A, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360A | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 7.8 | 1.9 | 4.1 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360A, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.24 | 0.0018 | 130 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.7 | 0.065 | 11 | pH 7 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360R | Saccharomyces cerevisiae | L-glutamine | 1.13 | 1.9 | 0.59 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360R, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360R | Saccharomyces cerevisiae | L-glutamine1 h incubation | 0.00131 | 1.7 | 7 × 10⁻⁴ | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360R, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360R | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 0.61 | 1.24 | 0.49 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360R, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360R | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.29 | 0.0023 | 110 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360R, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant K360R | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.31 | 0.072 | 4.3 | pH 7 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant K360R, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239A | Saccharomyces cerevisiae | L-glutamine | 0.0069 | 6.5 | 0.0011 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239A, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239A | Saccharomyces cerevisiae | L-glutamine1 h incubation | 0.0014 | 2.3 | 6 × 10⁻⁴ | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239A, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239A | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 0.18 | 0.35 | 0.52 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239A, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.0043 | 0.003 | 1.4 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239A | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.15 | 0.053 | 2.8 | pH 7 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239A, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239H | Saccharomyces cerevisiae | L-glutamine | 0.006 | 2.1 | 0.0028 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239H, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239H | Saccharomyces cerevisiae | L-glutamine1 h incubation | 0.0016 | 0.8 | 0.0021 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239H, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239H | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 0.24 | 1.62 | 0.15 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239H, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239H | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.039 | 0.0079 | 0.5 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239H, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239H | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.21 | 0.075 | 2.9 | pH 7 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239H, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239K | Saccharomyces cerevisiae | L-glutamine | 0.009 | 1.3 | 0.007 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239K, L-glutamine | |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239K | Saccharomyces cerevisiae | L-glutamine1 h incubation | 5 × 10⁻⁴ | 0.6 | 8 × 10⁻⁴ | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239K, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239K | Saccharomyces cerevisiae | L-glutaminePRFAR constant at 100 µM; 15 min incubation | 0.366 | 1.04 | 0.35 | pH 7, 30 °C | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239K, L-glutamine |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239K | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.0087 | 0.0016 | 5.5 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239K, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | |
| imidazole glycerol phosphate synthase (IGP synthase)variant R239K | Saccharomyces cerevisiae | N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide | 0.3 | 0.08 | 3.8 | pH 7 | Open record: imidazole glycerol phosphate synthase (IGP synthase) variant R239K, N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide |