Values CatLog read from this paper
Structure and mechanism of spermidine synthases
PMID 17585781doi:10.1021/bi602498kOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 18 records (24 values) from this paper: spermidine synthase (TmSpdSyn), spermidine synthase (HsSpdSyn) from Thermotoga maritima, Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 2 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| spermidine synthase (HsSpdSyn) | Homo sapiens | 1,4-diaminobutane | 1.9 | 0.02 | 95 calc. | pH 7.5, 37 °C | Open record: spermidine synthase (HsSpdSyn), 1,4-diaminobutane |
| spermidine synthase (HsSpdSyn) | Homo sapiens | decarboxylated S-adenosylmethionine | — | 9 × 10⁻⁴ | — | pH 7.5, 37 °C | Open record: spermidine synthase (HsSpdSyn), decarboxylated S-adenosylmethionine |
| spermidine synthase (TmSpdSyn) | Thermotoga maritima | 1,4-diaminobutaneTable 2 | 0.77 | 0.019 | 41 calc. | pH 7.5, 37 °C | Open record: spermidine synthase (TmSpdSyn), 1,4-diaminobutane |
| spermidine synthase (TmSpdSyn) | Thermotoga maritima | 1,4-diaminobutane | 22.7 | — | — | pH 7.5, 80 °C | Open record: spermidine synthase (TmSpdSyn), 1,4-diaminobutane |
| spermidine synthase (TmSpdSyn) | Thermotoga maritima | 1,4-diaminobutaneTable 3 | — | — | 40.53 | pH 7.5, 37 °C | Open record: spermidine synthase (TmSpdSyn), 1,4-diaminobutane |
| spermidine synthase (TmSpdSyn) | Thermotoga maritima | decarboxylated S-adenosylmethionineTable 2 | — | 7.5 × 10⁻⁴ | — | pH 7.5, 37 °C | Open record: spermidine synthase (TmSpdSyn), decarboxylated S-adenosylmethionine |
| spermidine synthase (TmSpdSyn) | Thermotoga maritima | decarboxylated S-adenosylmethionineTable 3 | — | — | 1027 | pH 7.5, 37 °C | Open record: spermidine synthase (TmSpdSyn), decarboxylated S-adenosylmethionine |
| spermidine synthase (TmSpdSyn)variant D101I | Thermotoga maritima | 1,4-diaminobutane | 4 × 10⁻⁴ | — | 0.0027 | pH 7.5, 37 °C | Open record: spermidine synthase (TmSpdSyn) variant D101I, 1,4-diaminobutane |
| spermidine synthase (TmSpdSyn)variant D101I | Thermotoga maritima | 1,4-diaminobutane | 0.012 | — | — | pH 7.5, 80 °C | Open record: spermidine synthase (TmSpdSyn) variant D101I, 1,4-diaminobutane |
| spermidine synthase (TmSpdSyn)variant D170A | Thermotoga maritima | 1,4-diaminobutane | 1.5 × 10⁻⁴ | — | 3 × 10⁻⁵ | pH 7.5, 37 °C | Open record: spermidine synthase (TmSpdSyn) variant D170A, 1,4-diaminobutane |
| spermidine synthase (TmSpdSyn)variant D170A | Thermotoga maritima | 1,4-diaminobutane | 0.014 | — | — | pH 7.5, 80 °C | Open record: spermidine synthase (TmSpdSyn) variant D170A, 1,4-diaminobutane |
| spermidine synthase (TmSpdSyn)variant D170A | Thermotoga maritima | decarboxylated S-adenosylmethionine | — | — | 0.06 | pH 7.5, 37 °C | Open record: spermidine synthase (TmSpdSyn) variant D170A, decarboxylated S-adenosylmethionine |
| spermidine synthase (TmSpdSyn)variant D173A | Thermotoga maritima | 1,4-diaminobutane | 0.003 | — | 0.0035 | pH 7.5, 37 °C | Open record: spermidine synthase (TmSpdSyn) variant D173A, 1,4-diaminobutane |
| spermidine synthase (TmSpdSyn)variant D173A | Thermotoga maritima | 1,4-diaminobutane | 1.5 | — | — | pH 7.5, 80 °C | Open record: spermidine synthase (TmSpdSyn) variant D173A, 1,4-diaminobutane |
| spermidine synthase (TmSpdSyn)variant D173A | Thermotoga maritima | decarboxylated S-adenosylmethionine | — | — | 2 | pH 7.5, 37 °C | Open record: spermidine synthase (TmSpdSyn) variant D173A, decarboxylated S-adenosylmethionine |
| spermidine synthase (TmSpdSyn)variant Y76F | Thermotoga maritima | 1,4-diaminobutane | 0.005 | — | 0.0215 | pH 7.5, 37 °C | Open record: spermidine synthase (TmSpdSyn) variant Y76F, 1,4-diaminobutane |
| spermidine synthase (TmSpdSyn)variant Y76F | Thermotoga maritima | 1,4-diaminobutane | 8.1 | — | — | pH 7.5, 80 °C | Open record: spermidine synthase (TmSpdSyn) variant Y76F, 1,4-diaminobutane |
| spermidine synthase (TmSpdSyn)variant Y76F | Thermotoga maritima | decarboxylated S-adenosylmethionine | — | — | 1.04 | pH 7.5, 37 °C | Open record: spermidine synthase (TmSpdSyn) variant Y76F, decarboxylated S-adenosylmethionine |