CatLogenzyme kinetics catalog

EC 2.5.1.16: spermidine synthase

TransferasesOpen in Browse

CatLog read 26 records for EC 2.5.1.16 from 3 papers, for 4 organisms. Names in these papers: spermidine synthase (TmSpdSyn), agmatine/cadaverine aminopropyl transferase (ACAPT), TK0147 (aminopropyl transferase), spermidine synthase (HsSpdSyn).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 34 records for EC 2.5.1.16 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.5.1.16 in Browse.

Papers

PaperOrganismsRecords
Structure and mechanism of spermidine synthasesHomo sapiens, Thermotoga maritima18
The first agmatine/cadaverine aminopropyl transferase: biochemical and structural characterization of an enzyme involved in polyamine biosynthesis in the hyperthermophilic archaeon Pyrococcus…Pyrococcus furiosus5
Dual biosynthesis pathway for longer-chain polyamines in the hyperthermophilic archaeon Thermococcus kodakarensisThermococcus kodakarensis3

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
agmatine/cadaverine aminopropyl transferase (ACAPT)Pyrococcus furiosus1,5-diaminopentane2.093.7670.55pH 7.4, 70 °CPMID 17545282Open
agmatine/cadaverine aminopropyl transferase (ACAPT)Pyrococcus furiosusAgmatine0.10.007613.4pH 7.4, 70 °CPMID 17545282Open
agmatine/cadaverine aminopropyl transferase (ACAPT)Pyrococcus furiosusbutane-1,4-diamine0.187.7030.023pH 7.4, 70 °CPMID 17545282Open
agmatine/cadaverine aminopropyl transferase (ACAPT)Pyrococcus furiosuspropane-1,3-diamine0.061.8770.032pH 7.4, 70 °CPMID 17545282Open
agmatine/cadaverine aminopropyl transferase (ACAPT)Pyrococcus furiosusS-adenosyl-(5')-3-methylthiopropylamine—0.02—pH 7.4, 70 °CPMID 17545282Open
spermidine synthase (HsSpdSyn)Homo sapiens1,4-diaminobutane1.90.0295 calc.pH 7.5, 37 °CPMID 17585781Open
spermidine synthase (HsSpdSyn)Homo sapiensdecarboxylated S-adenosylmethionine—9 × 10⁻⁴—pH 7.5, 37 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)Thermotoga maritima1,4-diaminobutaneTable 20.770.01941 calc.pH 7.5, 37 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)Thermotoga maritima1,4-diaminobutane22.7——pH 7.5, 80 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)Thermotoga maritima1,4-diaminobutaneTable 3——40.53pH 7.5, 37 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)Thermotoga maritimadecarboxylated S-adenosylmethionineTable 2—7.5 × 10⁻⁴—pH 7.5, 37 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)Thermotoga maritimadecarboxylated S-adenosylmethionineTable 3——1027pH 7.5, 37 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)variant D101IThermotoga maritima1,4-diaminobutane4 × 10⁻⁴—0.0027pH 7.5, 37 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)variant D101IThermotoga maritima1,4-diaminobutane0.012——pH 7.5, 80 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)variant D170AThermotoga maritima1,4-diaminobutane1.5 × 10⁻⁴—3 × 10⁻⁵pH 7.5, 37 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)variant D170AThermotoga maritima1,4-diaminobutane0.014——pH 7.5, 80 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)variant D170AThermotoga maritimadecarboxylated S-adenosylmethionine——0.06pH 7.5, 37 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)variant D173AThermotoga maritima1,4-diaminobutane0.003—0.0035pH 7.5, 37 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)variant D173AThermotoga maritima1,4-diaminobutane1.5——pH 7.5, 80 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)variant D173AThermotoga maritimadecarboxylated S-adenosylmethionine——2pH 7.5, 37 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)variant Y76FThermotoga maritima1,4-diaminobutane0.005—0.0215pH 7.5, 37 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)variant Y76FThermotoga maritima1,4-diaminobutane8.1——pH 7.5, 80 °CPMID 17585781Open
spermidine synthase (TmSpdSyn)variant Y76FThermotoga maritimadecarboxylated S-adenosylmethionine——1.04pH 7.5, 37 °CPMID 17585781Open
TK0147 (aminopropyl transferase)Thermococcus kodakarensisagmatine0.280.012222.5pH 9, 70 °CPMID 20675472Open
TK0147 (aminopropyl transferase)Thermococcus kodakarensiscadaverine0.020.08070.29pH 9, 70 °CPMID 20675472Open
TK0147 (aminopropyl transferase)Thermococcus kodakarensisputrescine0.31.0530.29pH 9, 70 °CPMID 20675472Open