Values CatLog read from this paper
Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1
PMID 15082749doi:10.1124/jpet.104.067116Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 24 records (24 values) from this paper: carboxylesterase CES1A1 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| carboxylesterase CES1A1 | Homo sapiens | d-threo-methylphenidate | 0.0032 | — | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, d-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | d-threo-methylphenidate | — | 0.0899 | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, d-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | d-threo-methylphenidate | — | — | 0.035 | pH 7, 25 °C | Open record: carboxylesterase CES1A1, d-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | d-threo-methylphenidate | 0.003 | — | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, d-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | d-threo-methylphenidate | — | 0.08 | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, d-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | d-threo-methylphenidate | — | — | 0.038 | pH 7, 25 °C | Open record: carboxylesterase CES1A1, d-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | d-threo-methylphenidaterecombinant; expressed in Sf9 insect cells | 0.0027 | — | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, d-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | d-threo-methylphenidaterecombinant; expressed in Sf9 insect cells | — | 0.1262 | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, d-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | d-threo-methylphenidaterecombinant; expressed in Sf9 insect cells | — | — | 0.022 | pH 7, 25 °C | Open record: carboxylesterase CES1A1, d-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | d-threo-methylphenidaterecombinant; expressed in Sf9 insect cells | 0.0028 | — | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, d-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | d-threo-methylphenidaterecombinant; expressed in Sf9 insect cells | — | 0.1104 | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, d-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | d-threo-methylphenidaterecombinant; expressed in Sf9 insect cells | — | — | 0.027 | pH 7, 25 °C | Open record: carboxylesterase CES1A1, d-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | l-threo-methylphenidate | 0.0057 | — | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, l-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | l-threo-methylphenidate | — | 0.0438 | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, l-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | l-threo-methylphenidate | — | — | 0.128 | pH 7, 25 °C | Open record: carboxylesterase CES1A1, l-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | l-threo-methylphenidate | 0.0047 | — | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, l-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | l-threo-methylphenidate | — | 0.0401 | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, l-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | l-threo-methylphenidate | — | — | 0.117 | pH 7, 25 °C | Open record: carboxylesterase CES1A1, l-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | l-threo-methylphenidaterecombinant; expressed in Sf9 insect cells | 0.0052 | — | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, l-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | l-threo-methylphenidaterecombinant; expressed in Sf9 insect cells | — | 0.0401 | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, l-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | l-threo-methylphenidaterecombinant; expressed in Sf9 insect cells | — | — | 0.13 | pH 7, 25 °C | Open record: carboxylesterase CES1A1, l-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | l-threo-methylphenidaterecombinant; expressed in Sf9 insect cells | 0.006 | — | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, l-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | l-threo-methylphenidaterecombinant; expressed in Sf9 insect cells | — | 0.0471 | — | pH 7, 25 °C | Open record: carboxylesterase CES1A1, l-threo-methylphenidate |
| carboxylesterase CES1A1 | Homo sapiens | l-threo-methylphenidaterecombinant; expressed in Sf9 insect cells | — | — | 0.127 | pH 7, 25 °C | Open record: carboxylesterase CES1A1, l-threo-methylphenidate |