CatLogenzyme kinetics catalog

Values CatLog read from this paper

Human missense variants in F3 impair the initiation of blood coagulation

PMID 41100734doi:10.1182/blood.2025029571Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 20 records (60 values) from this paper: tissue factor-factor VIIa complex (sTF-FVIIa) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
tissue factor-factor VIIa complex (sTF-FVIIa)Homo sapienscoagulation factor IX0.02380.0025849.2Open
tissue factor-factor VIIa complex (sTF-FVIIa)Homo sapienscoagulation factor X0.17535.323 × 10⁻⁵3.65 × 10³Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant D90EHomo sapienscoagulation factor IX0.00220.0076071.5Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant D90EHomo sapienscoagulation factor X0.01082.01 × 10⁻⁵730Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant D90NHomo sapienscoagulation factor X0.00275.035 × 10⁻⁵39.3Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant D93GHomo sapienscoagulation factor IX0.01680.0018399.2Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant D93GHomo sapienscoagulation factor X0.24385.636 × 10⁻⁵4.32 × 10³Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant F172LHomo sapienscoagulation factor IX0.01450.0018538Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant F172LHomo sapienscoagulation factor X0.21835.531 × 10⁻⁵3.88 × 10³Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant G196RHomo sapienscoagulation factor IX0.00450.0015713Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant G196RHomo sapienscoagulation factor X0.02652.076 × 10⁻⁴125.7Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant I54VHomo sapienscoagulation factor IX0.02280.0022447.2Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant I54VHomo sapienscoagulation factor X0.21985.762 × 10⁻⁵3.72 × 10³Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant K197NHomo sapienscoagulation factor IX0.00430.0028911.7Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant K197NHomo sapienscoagulation factor X0.01073.792 × 10⁻⁵300Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant R163WHomo sapienscoagulation factor IX0.02030.002358.7Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant R163WHomo sapienscoagulation factor X0.23135.598 × 10⁻⁵4.07 × 10³Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant T36AHomo sapienscoagulation factor IX0.02870.0026077.3Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant T36AHomo sapienscoagulation factor X0.22935.056 × 10⁻⁵4.6 × 10³Open
tissue factor-factor VIIa complex (sTF-FVIIa)variant Y103SHomo sapienscoagulation factor X0.23185.894 × 10⁻⁵4 × 10³Open