Values CatLog read from this paper
Extended Recognition of the Histone H3 Tail by Histone Demethylase KDM5A
PMID 31985200doi:10.1021/acs.biochem.9b01036Open in Browse
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CatLog read 14 records (42 values) from this paper: lysine demethylase KDM5A (histone H3K4 demethylase) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal 13mer peptide with Lys4 trimethylated (H3K4me3), lacking the K14-K18 basic patch | 0.111 | 0.4887 | 0.2276 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal 13mer peptide with Lys4 trimethylated (H3K4me3), lacking the K14-K18 basic patch | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal 18mer peptide with Lys4 trimethylated (H3K4me3) | 0.078 | 0.0623 | 1.249 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal 18mer peptide with Lys4 trimethylated (H3K4me3) | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal 18mer peptide with Lys4 trimethylated (H3K4me3), K14A/R17A/K18A substitutions in the peptide | 0.108 | 0.5141 | 0.2109 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal 18mer peptide with Lys4 trimethylated (H3K4me3), K14A/R17A/K18A substitutions in the peptide | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal 18mer peptide with Lys4 trimethylated and Lys14 and Lys18 acetylated | 0.101 | 0.2491 | 0.4046 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal 18mer peptide with Lys4 trimethylated and Lys14 and Lys18 acetylated | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3) | 0.052 | 0.0125 | 4.126 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3) | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3)effector peptide presence not stated in Table 2 caption | 0.057 | 0.0249 | 2.289 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3) | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), K9A substitution in the peptide | 0.061 | 0.0219 | 2.791 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), K9A substitution in the peptide | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), Q5A substitution in the peptide | 0.056 | 0.4152 | 0.1344 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), Q5A substitution in the peptide | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), R2A substitution in the peptide | 0.069 | 0.1536 | 0.4518 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), R2A substitution in the peptide | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), R8A substitution in the peptide | 0.054 | 0.0551 | 0.9807 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), R8A substitution in the peptide | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), T3A substitution in the peptide | 0.056 | 0.009 | 6.232 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), T3A substitution in the peptide | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), T6A substitution in the peptide | 0.075 | 0.0965 | 0.7727 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), T6A substitution in the peptide | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), T6S substitution in the peptide | 0.07 | 0.0147 | 4.756 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), T6S substitution in the peptide | |
| lysine demethylase KDM5A (histone H3K4 demethylase) | Homo sapiens | histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), T6V substitution in the peptide | 0.05 | 0.0394 | 1.258 | Open record: lysine demethylase KDM5A (histone H3K4 demethylase), histone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), T6V substitution in the peptide |