CatLogenzyme kinetics catalog

EC 1.14.11.67: [histone H3]-trimethyl-L-lysine4 demethylase

OxidoreductasesOpen in Browse

CatLog read 14 records for EC 1.14.11.67 from 1 paper, for 1 organism. Names in these papers: lysine demethylase KDM5A (histone H3K4 demethylase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 6 records for EC 1.14.11.67 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.14.11.67 in Browse.

Papers

PaperOrganismsRecords
Extended Recognition of the Histone H3 Tail by Histone Demethylase KDM5AHomo sapiens14

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal 13mer peptide with Lys4 trimethylated (H3K4me3), lacking the K14-K18 basic patch0.1110.48870.2276PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal 18mer peptide with Lys4 trimethylated (H3K4me3)0.0780.06231.249PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal 18mer peptide with Lys4 trimethylated (H3K4me3), K14A/R17A/K18A substitutions in the peptide0.1080.51410.2109PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal 18mer peptide with Lys4 trimethylated and Lys14 and Lys18 acetylated0.1010.24910.4046PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3)0.0520.01254.126PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3)effector peptide presence not stated in Table 2 caption0.0570.02492.289PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), K9A substitution in the peptide0.0610.02192.791PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), Q5A substitution in the peptide0.0560.41520.1344PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), R2A substitution in the peptide0.0690.15360.4518PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), R8A substitution in the peptide0.0540.05510.9807PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), T3A substitution in the peptide0.0560.0096.232PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), T6A substitution in the peptide0.0750.09650.7727PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), T6S substitution in the peptide0.070.01474.756PMID 31985200Open
lysine demethylase KDM5A (histone H3K4 demethylase)Homo sapienshistone H3 N-terminal peptide residues 1-21 with Lys4 trimethylated (H3K4me3), T6V substitution in the peptide0.050.03941.258PMID 31985200Open