Values CatLog read from this paper
A paradigm shift for the amino acid editing mechanism of human cytoplasmic leucyl-tRNA synthetase
PMID 19702327doi:10.1021/bi901111yOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (15 values) from this paper: human cytoplasmic leucyl-tRNA synthetase (hscLeuRS) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 1 kcat/Km value marked “calc.” from kcat and Km; no printed kcat/Km was read for that record.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| human cytoplasmic leucyl-tRNA synthetase (hscLeuRS) | Homo sapiens | isoleucine | 0.34 | 2.04 | 0.16 | pH 8 | Open record: human cytoplasmic leucyl-tRNA synthetase (hscLeuRS), isoleucine |
| human cytoplasmic leucyl-tRNA synthetase (hscLeuRS) | Homo sapiens | leucine | 2.1 | 0.024 | 94.3 | pH 8 | Open record: human cytoplasmic leucyl-tRNA synthetase (hscLeuRS), leucine |
| human cytoplasmic leucyl-tRNA synthetase (hscLeuRS)variant D399A | Homo sapiens | isoleucine | 0.51 | 3.3 | 0.17 | pH 8 | Open record: human cytoplasmic leucyl-tRNA synthetase (hscLeuRS) variant D399A, isoleucine |
| human cytoplasmic leucyl-tRNA synthetase (hscLeuRS)variant D399A | Homo sapiens | isoleucine | 0.0018 | — | — | pH 7.6, 30 °C | Open record: human cytoplasmic leucyl-tRNA synthetase (hscLeuRS) variant D399A, isoleucine |
| human cytoplasmic leucyl-tRNA synthetase (hscLeuRS)variant D399A | Homo sapiens | isoleucine | 0.06 | 1.8 | 0.033 calc. | pH 7.5 | Open record: human cytoplasmic leucyl-tRNA synthetase (hscLeuRS) variant D399A, isoleucine |
| human cytoplasmic leucyl-tRNA synthetase (hscLeuRS)variant D399A | Homo sapiens | leucine | 5.6 | 0.9 | 5.6 | pH 8 | Open record: human cytoplasmic leucyl-tRNA synthetase (hscLeuRS) variant D399A, leucine |