Values CatLog read from this paper
A monofunctional-like mutant of DNA glycosylase NTHL1 changes the dynamics of DNA repair during acute oxidative stress
PMID 41763309doi:10.1016/j.jbc.2026.111332Open in Browse
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CatLog read 4 records (4 values) from this paper: endonuclease III-like protein 1 (NTHL1), bifunctional DNA glycosylase from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| endonuclease III-like protein 1 (NTHL1), bifunctional DNA glycosylase | Homo sapiens | 22-mer oligonucleotide DNA duplex containing thymine glycol (Tg) opposite A (fluorophore/quencher molecular beacon)NTHL1 alone (no APE1) | — | 9.7 × 10⁻⁷ | — | pH 8, 25 °C | Open record: endonuclease III-like protein 1 (NTHL1), bifunctional DNA glycosylase, 22-mer oligonucleotide DNA duplex containing thymine glycol (Tg) opposite A (fluorophore/quencher molecular beacon) |
| endonuclease III-like protein 1 (NTHL1), bifunctional DNA glycosylase | Homo sapiens | 22-mer oligonucleotide DNA duplex containing thymine glycol (Tg) opposite A (fluorophore/quencher molecular beacon)with 2 nM APE1 (in excess); 5 nM NTHL1 | — | 1.02 × 10⁻⁵ | — | pH 8, 25 °C | Open record: endonuclease III-like protein 1 (NTHL1), bifunctional DNA glycosylase, 22-mer oligonucleotide DNA duplex containing thymine glycol (Tg) opposite A (fluorophore/quencher molecular beacon) |
| endonuclease III-like protein 1 (NTHL1), bifunctional DNA glycosylasevariant L224K | Homo sapiens | 22-mer oligonucleotide DNA duplex containing thymine glycol (Tg) opposite A (fluorophore/quencher molecular beacon)NTHL1 alone (no APE1) | — | 2.54 × 10⁻⁵ | — | pH 8, 25 °C | Open record: endonuclease III-like protein 1 (NTHL1), bifunctional DNA glycosylase variant L224K, 22-mer oligonucleotide DNA duplex containing thymine glycol (Tg) opposite A (fluorophore/quencher molecular beacon) |
| endonuclease III-like protein 1 (NTHL1), bifunctional DNA glycosylasevariant L224K | Homo sapiens | 22-mer oligonucleotide DNA duplex containing thymine glycol (Tg) opposite A (fluorophore/quencher molecular beacon)with 2 nM APE1 (in excess); 5 nM NTHL1 | — | 1.02 × 10⁻⁴ | — | pH 8, 25 °C | Open record: endonuclease III-like protein 1 (NTHL1), bifunctional DNA glycosylase variant L224K, 22-mer oligonucleotide DNA duplex containing thymine glycol (Tg) opposite A (fluorophore/quencher molecular beacon) |