Values CatLog read from this paper
Activation loop 3 and the 170 loop interact in the active conformation of coagulation factor VIIa
PMID 19490111doi:10.1111/j.1742-4658.2009.07028.xOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (24 values) from this paper: factor VIIa from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| factor VIIa | Homo sapiens | D-Ile-Pro-Arg-p-nitroanilidefree FVIIa; no tissue factor | — | 10 | — | pH 7.4 | Open record: factor VIIa, D-Ile-Pro-Arg-p-nitroanilide |
| factor VIIa | Homo sapiens | D-Ile-Pro-Arg-p-nitroanilidewith 150 nM soluble tissue factor (sTF, residues 1-219) | — | 1.8 | — | pH 7.4 | Open record: factor VIIa, D-Ile-Pro-Arg-p-nitroanilide |
| factor VIIa | Homo sapiens | factor Xfree FVIIa; no tissue factor | 4.9 × 10⁻⁵ | 0.003 | 0.016 | pH 7.4 | Open record: factor VIIa, factor X |
| factor VIIa | Homo sapiens | factor Xwith 150 nM soluble tissue factor (sTF, residues 1-219) | 0.0027 | 0.0019 | 1.4 | pH 7.4 | Open record: factor VIIa, factor X |
| factor VIIa | Homo sapiens | factor Xwith 1 pM lipidated tissue factor | 0.004 | 1.5 × 10⁻⁵ | 270 | pH 7.4 | Open record: factor VIIa, factor X |
| factor VIIa | Homo sapiens | pyroGlu-Pro-Arg-p-nitroanilide | — | 1.9 | — | pH 7.4 | Open record: factor VIIa, pyroGlu-Pro-Arg-p-nitroanilide |
| factor VIIavariant G372A | Homo sapiens | D-Ile-Pro-Arg-p-nitroanilidefree FVIIa; no tissue factor | — | 14 | — | pH 7.4 | Open record: factor VIIa variant G372A, D-Ile-Pro-Arg-p-nitroanilide |
| factor VIIavariant G372A | Homo sapiens | D-Ile-Pro-Arg-p-nitroanilidewith 150 nM soluble tissue factor (sTF, residues 1-219) | — | 7.1 | — | pH 7.4 | Open record: factor VIIa variant G372A, D-Ile-Pro-Arg-p-nitroanilide |
| factor VIIavariant G372A | Homo sapiens | factor Xfree FVIIa; no tissue factor | 7 × 10⁻⁶ | 0.0054 | 0.0013 | pH 7.4 | Open record: factor VIIa variant G372A, factor X |
| factor VIIavariant G372A | Homo sapiens | factor Xwith 150 nM soluble tissue factor (sTF, residues 1-219) | 6.2 × 10⁻⁴ | 0.0032 | 0.19 | pH 7.4 | Open record: factor VIIa variant G372A, factor X |
| factor VIIavariant G372A | Homo sapiens | factor Xwith 1 pM lipidated tissue factor | 0.0021 | 1.2 × 10⁻⁵ | 180 | pH 7.4 | Open record: factor VIIa variant G372A, factor X |
| factor VIIavariant G372A | Homo sapiens | pyroGlu-Pro-Arg-p-nitroanilide | — | 3.9 | — | pH 7.4 | Open record: factor VIIa variant G372A, pyroGlu-Pro-Arg-p-nitroanilide |