Values CatLog read from this paper
Mutational analysis of the two zinc-binding sites of the Bacillus cereus 569/H/9 metallo-beta-lactamase
PMID 11964169doi:10.1042/0264-6021:3630687Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 86 records (118 values) from this paper: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) from Bacillus cereus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) | Bacillus cereus | benzylpenicillin | 230 | 0.17 | 1.36 × 10³ | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II), benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) | Bacillus cereus | cefotaxime0.4 µM ZnSO4 | — | — | 820 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II), cefotaxime |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) | Bacillus cereus | cefotaxime100 µM ZnSO4 | — | — | 1.3 × 10³ | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II), cefotaxime |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) | Bacillus cereus | cefoxitin | — | — | 0.2 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II), cefoxitin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) | Bacillus cereus | cephaloridine0.4 µM ZnSO4 | — | — | 11.5 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II), cephaloridine |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) | Bacillus cereus | cephaloridine100 µM ZnSO4 | — | — | 46 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II), cephaloridine |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) | Bacillus cereus | imipenem0.4 µM ZnSO4 | — | — | 170 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II), imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) | Bacillus cereus | imipenem100 µM ZnSO4 | — | — | 220 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II), imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) | Bacillus cereus | nitrocefinno zinc added; [Zn2+] approx. 0.4 µM | 43 | 0.009 | 4.9 × 10³ | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II), nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) | Bacillus cereus | nitrocefin[Zn2+] 0.4 µM | — | — | 1.5 × 10³ | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II), nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) | Bacillus cereus | nitrocefin[Zn2+] 10 µM | — | — | 2.3 × 10³ | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II), nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) | Bacillus cereus | nitrocefin[Zn2+] 100 µM | — | — | 3.1 × 10³ | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II), nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221A | Bacillus cereus | cefotaxime0.4 µM ZnSO4 | — | — | 0.65 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221A, cefotaxime |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221A | Bacillus cereus | cefotaxime100 µM ZnSO4 | — | — | 200 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221A, cefotaxime |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221A | Bacillus cereus | cephaloridine | — | — | 11 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221A, cephaloridine |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221A | Bacillus cereus | imipenem0.4 µM ZnSO4 | — | — | 0.4 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221A, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221A | Bacillus cereus | imipenem100 µM ZnSO4 | — | — | 4 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221A, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221A | Bacillus cereus | nitrocefin[Zn2+] 0.4 µM | — | — | 1 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221A, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221A | Bacillus cereus | nitrocefin[Zn2+] 10 µM | — | — | 87 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221A, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221A | Bacillus cereus | nitrocefin[Zn2+] 20 µM | — | — | 87 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221A, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221A | Bacillus cereus | nitrocefin[Zn2+] 50 µM | — | — | 110 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221A, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221A | Bacillus cereus | nitrocefin[Zn2+] 100 µM | — | — | 280 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221A, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | benzylpenicillinno zinc added; [Zn2+] approx. 0.4 µM | 15 | 0.475 | 31 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | benzylpenicillin100 µM Zn2+ (row "C221S (100 µM Zn2+)") | 200 | 0.775 | 262 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | cefotaxime0.4 µM ZnSO4 | — | — | 1 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, cefotaxime |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | cefotaxime100 µM ZnSO4 | — | — | 130 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, cefotaxime |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | cephaloridine | — | — | 6.6 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, cephaloridine |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | imipenem0.4 µM ZnSO4 | — | — | 1 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | imipenem100 µM ZnSO4 | — | — | 16 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | nitrocefinno zinc added; [Zn2+] approx. 0.4 µM | 1.3 | 0.008 | 166 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | nitrocefin100 µM Zn2+ (row "C221S (100 µM Zn2+)") | 63 | 0.021 | 3 × 10³ | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | nitrocefin[Zn2+] 0.4 µM | — | — | 2.5 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | nitrocefin[Zn2+] 10 µM | — | — | 340 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | nitrocefin[Zn2+] 20 µM | — | — | 340 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | nitrocefin[Zn2+] 50 µM | — | — | 370 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant C221S | Bacillus cereus | nitrocefin[Zn2+] 100 µM | — | — | 680 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant C221S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant D120N | Bacillus cereus | benzylpenicillin | 3.5 | 0.44 | 7.9 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant D120N, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant D120N | Bacillus cereus | imipenem0.4 µM ZnSO4 | — | — | 2.5 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant D120N, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant D120N | Bacillus cereus | imipenem100 µM ZnSO4 | — | — | 2.8 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant D120N, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant D120N | Bacillus cereus | nitrocefin | 2.2 | 0.133 | 16.5 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant D120N, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H116S | Bacillus cereus | benzylpenicillin | 47 | 0.53 | 89 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H116S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H116S | Bacillus cereus | nitrocefinno zinc added; [Zn2+] approx. 0.4 µM | 44 | 0.18 | 227 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H116S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H116S | Bacillus cereus | nitrocefin[Zn2+] 0.4 µM | — | — | 240 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H116S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H116S | Bacillus cereus | nitrocefin[Zn2+] 20 µM | — | — | 300 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H116S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H116S | Bacillus cereus | nitrocefin[Zn2+] 100 µM | — | — | 330 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H116S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H118S | Bacillus cereus | benzylpenicillin | 36 | 2.3 | 12.2 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H118S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H118S | Bacillus cereus | imipenem0.4 µM ZnSO4 | — | — | 5.3 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H118S, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H118S | Bacillus cereus | imipenem100 µM ZnSO4 | — | — | 8.8 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H118S, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H118S | Bacillus cereus | nitrocefinno zinc added; [Zn2+] approx. 0.4 µM | 5 | 0.22 | 21.6 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H118S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H118S | Bacillus cereus | nitrocefin[Zn2+] 0.4 µM | — | — | 42 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H118S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H118S | Bacillus cereus | nitrocefin[Zn2+] 10 µM | — | — | 60 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H118S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H118S | Bacillus cereus | nitrocefin[Zn2+] 20 µM | — | — | 59 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H118S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H118S | Bacillus cereus | nitrocefin[Zn2+] 100 µM | — | — | 76 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H118S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | benzylpenicillin | 7 | 5.7 | 1.23 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | benzylpenicillin5 µM ZnSO4 | — | — | 0.1 | pH 5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | benzylpenicillin10 µM ZnSO4 | — | — | 0.25 | pH 5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | benzylpenicillin100 µM ZnSO4 | — | — | 0.43 | pH 5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | benzylpenicillin1 mM ZnSO4 | — | — | 1.7 | pH 5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | benzylpenicillin5 µM ZnSO4 | — | — | 2.2 | pH 7, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | benzylpenicillin10 µM ZnSO4 | — | — | 2.8 | pH 7, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | benzylpenicillin100 µM ZnSO4 | — | — | 3.7 | pH 7, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | benzylpenicillin1 mM ZnSO4 | — | — | 6.2 | pH 7, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | cefotaxime0.4 µM ZnSO4 | — | — | 4 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, cefotaxime |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | cefotaxime100 µM ZnSO4 | — | — | 14.5 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, cefotaxime |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | cephaloridine0.4 µM ZnSO4 | — | — | 1.5 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, cephaloridine |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | cephaloridine100 µM ZnSO4 | — | — | 1.6 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, cephaloridine |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | imipenem0.4 µM ZnSO4 | — | — | 1.5 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | imipenem100 µM ZnSO4 | — | — | 3 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | nitrocefinno zinc added; [Zn2+] approx. 0.4 µM | 0.2 | 0.16 | 1.4 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | nitrocefin[Zn2+] 0.4 µM | — | — | 6.6 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | nitrocefin[Zn2+] 10 µM | — | — | 13 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | nitrocefin[Zn2+] 20 µM | — | — | 11 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H196S | Bacillus cereus | nitrocefin[Zn2+] 100 µM | — | — | 13.5 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H196S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H263S | Bacillus cereus | benzylpenicillin | — | — | 2.6 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H263S, benzylpenicillin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H263S | Bacillus cereus | cefotaxime | — | — | 2.5 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H263S, cefotaxime |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H263S | Bacillus cereus | cephaloridine | — | — | 0.19 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H263S, cephaloridine |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H263S | Bacillus cereus | imipenem0.4 µM ZnSO4 | — | — | 2 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H263S, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H263S | Bacillus cereus | imipenem100 µM ZnSO4 | — | — | 2.4 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H263S, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H263S | Bacillus cereus | nitrocefinno zinc added; [Zn2+] approx. 0.4 µM | 1.3 | 0.365 | 3.6 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H263S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H263S | Bacillus cereus | nitrocefin[Zn2+] 0.4 µM | — | — | 2.1 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H263S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H263S | Bacillus cereus | nitrocefin[Zn2+] 10 µM | — | — | 3.2 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H263S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H263S | Bacillus cereus | nitrocefin[Zn2+] 20 µM | — | — | 4.3 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H263S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant H263S | Bacillus cereus | nitrocefin[Zn2+] 100 µM | — | — | 10 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant H263S, nitrocefin |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant N233Y | Bacillus cereus | imipenem0.4 µM ZnSO4 | — | — | 28 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant N233Y, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant N233Y | Bacillus cereus | imipenem100 µM ZnSO4 | — | — | 110 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant N233Y, imipenem |
| BcII metallo-beta-lactamase (Zn2+-beta-lactamase II)variant N233Y | Bacillus cereus | nitrocefin | 6 | 0.017 | 330 | pH 7.5, 30 °C | Open record: BcII metallo-beta-lactamase (Zn2+-beta-lactamase II) variant N233Y, nitrocefin |