Values CatLog read from this paper
Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10
PMID 18087047doi:10.1073/pnas.0705659105Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 18 records (42 values) from this paper: AKR1B10 (human small intestine aldose reductase), AKR1B1 (aldose reductase) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 1.1.1.21, EC 1.1.1.54, EC 1.1.1.300, EC 1.1.1.372
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| AKR1B1 (aldose reductase) | Homo sapiens | (S)-all-trans-4-hydroxyretinaldehyde | 0.0967 | — | — | pH 7.5, 25 °C | Open record: AKR1B1 (aldose reductase), (S)-all-trans-4-hydroxyretinaldehyde |
| AKR1B1 (aldose reductase) | Homo sapiens | 9-cis-retinaldehyde | 0.012 | 4 × 10⁻⁴ | 25 | pH 7.4, 37 °C | Open record: AKR1B1 (aldose reductase), 9-cis-retinaldehyde |
| AKR1B1 (aldose reductase) | Homo sapiens | all-trans-retinaldehyde | 0.0062 | — | — | pH 7.5, 25 °C | Open record: AKR1B1 (aldose reductase), all-trans-retinaldehyde |
| AKR1B1 (aldose reductase) | Homo sapiens | D,L-glyceraldehyde | 0.52 | 0.05 | 11 | pH 7.4, 37 °C | Open record: AKR1B1 (aldose reductase), D,L-glyceraldehyde |
| AKR1B10 (human small intestine aldose reductase) | Homo sapiens | (S)-all-trans-4-hydroxyretinaldehyde | 0.288 | — | — | pH 7.5, 25 °C | Open record: AKR1B10 (human small intestine aldose reductase), (S)-all-trans-4-hydroxyretinaldehyde |
| AKR1B10 (human small intestine aldose reductase) | Homo sapiens | 9-cis-retinaldehyde | 0.015 | 7 × 10⁻⁴ | 21.7 | pH 7.4, 37 °C | Open record: AKR1B10 (human small intestine aldose reductase), 9-cis-retinaldehyde |
| AKR1B10 (human small intestine aldose reductase) | Homo sapiens | all-trans-retinaldehyde | 0.297 | — | — | pH 7.5, 25 °C | Open record: AKR1B10 (human small intestine aldose reductase), all-trans-retinaldehyde |
| AKR1B10 (human small intestine aldose reductase) | Homo sapiens | D,L-glyceraldehyde | 0.58 | 6 | 0.1 | pH 7.4, 37 °C | Open record: AKR1B10 (human small intestine aldose reductase), D,L-glyceraldehyde |
| AKR1B10 (human small intestine aldose reductase)variant K125L | Homo sapiens | (S)-all-trans-4-hydroxyretinaldehyde | 0.308 | — | — | pH 7.5, 25 °C | Open record: AKR1B10 (human small intestine aldose reductase) variant K125L, (S)-all-trans-4-hydroxyretinaldehyde |
| AKR1B10 (human small intestine aldose reductase)variant K125L | Homo sapiens | 9-cis-retinaldehyde | 0.015 | 7 × 10⁻⁴ | 21.7 | pH 7.4, 37 °C | Open record: AKR1B10 (human small intestine aldose reductase) variant K125L, 9-cis-retinaldehyde |
| AKR1B10 (human small intestine aldose reductase)variant K125L | Homo sapiens | all-trans-retinaldehyde | 0.033 | 1.5 × 10⁻⁴ | 218 | pH 7.4, 37 °C | Open record: AKR1B10 (human small intestine aldose reductase) variant K125L, all-trans-retinaldehyde |
| AKR1B10 (human small intestine aldose reductase)variant K125L | Homo sapiens | all-trans-retinaldehyde | 0.0733 | — | — | pH 7.5, 25 °C | Open record: AKR1B10 (human small intestine aldose reductase) variant K125L, all-trans-retinaldehyde |
| AKR1B10 (human small intestine aldose reductase)variant K125L | Homo sapiens | D,L-glyceraldehyde | 0.593 | 5.2 | 0.12 | pH 7.4, 37 °C | Open record: AKR1B10 (human small intestine aldose reductase) variant K125L, D,L-glyceraldehyde |
| AKR1B10 (human small intestine aldose reductase)variant K125L/V301L | Homo sapiens | all-trans-retinaldehyde | 0.058 | 0.001 | 58.3 | pH 7.4, 37 °C | Open record: AKR1B10 (human small intestine aldose reductase) variant K125L/V301L, all-trans-retinaldehyde |
| AKR1B10 (human small intestine aldose reductase)variant K125L/V301L | Homo sapiens | D,L-glyceraldehyde | 0.59 | 7.3 | 0.082 | pH 7.4, 37 °C | Open record: AKR1B10 (human small intestine aldose reductase) variant K125L/V301L, D,L-glyceraldehyde |
| AKR1B10 (human small intestine aldose reductase)variant V301L | Homo sapiens | 9-cis-retinaldehyde | 0.01 | 3 × 10⁻⁴ | 30 | pH 7.4, 37 °C | Open record: AKR1B10 (human small intestine aldose reductase) variant V301L, 9-cis-retinaldehyde |
| AKR1B10 (human small intestine aldose reductase)variant V301L | Homo sapiens | all-trans-retinaldehyde | 0.128 | 6 × 10⁻⁴ | 212 | pH 7.4, 37 °C | Open record: AKR1B10 (human small intestine aldose reductase) variant V301L, all-trans-retinaldehyde |
| AKR1B10 (human small intestine aldose reductase)variant V301L | Homo sapiens | D,L-glyceraldehyde | 0.68 | 6 | 0.12 | pH 7.4, 37 °C | Open record: AKR1B10 (human small intestine aldose reductase) variant V301L, D,L-glyceraldehyde |