EC 1.1.1.372: D/L-glyceraldehyde reductase

OxidoreductasesOpen in Browse

CatLog read 80 records for EC 1.1.1.372 from 8 papers, for 4 organisms. Names in these papers: aldose reductase, AKR1B1 (aldose reductase), AKR1A1, aldose reductase AKR1B1 (human AR) and 5 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 20 records for EC 1.1.1.372 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.372 in Browse.

Papers

Papers with records for EC 1.1.1.372
Paper	Organisms	Records
The use of fluoro- and deoxy-substrate analogs to examine binding specificity and catalysis in the enzymes of the sorbitol pathway	Bos taurus (bovine)	26
Kinetic studies of AKR1B10, human aldose reductase-like protein: endogenous substrates and inhibition by steroids	Homo sapiens	22
Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members	Homo sapiens	14
Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes	Homo sapiens, Mus musculus	7
Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10	Homo sapiens	4
Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase	Homo sapiens	4
L-Idose: an attractive substrate alternative to D-glucose for measuring aldose reductase activity	Bos taurus	2
Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids	Homo sapiens	1

Records

Records for EC 1.1.1.372 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
AKR1A1	Homo sapiens	1,2-Naphthoquinone	14.68	0.144	103	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, 1,2-Naphthoquinone
AKR1A1	Homo sapiens	16-Ketoestrone	7.08	0.213	33	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, 16-Ketoestrone
AKR1A1	Homo sapiens	2-Chlorobenzaldehyde	0.15	0.657	0.33	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, 2-Chlorobenzaldehyde
AKR1A1	Homo sapiens	2-Nitrobenzaldehyde	0.05	0.054	0.83	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, 2-Nitrobenzaldehyde
AKR1A1	Homo sapiens	3-Chlorobenzaldehyde	7.37	2.413	3.3	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, 3-Chlorobenzaldehyde
AKR1A1	Homo sapiens	3-Nitrobenzaldehyde	1.68	1.008	1.7	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, 3-Nitrobenzaldehyde
AKR1A1	Homo sapiens	4-Carboxybenzaldehyde	6.97	0.024	280	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, 4-Carboxybenzaldehyde
AKR1A1	Homo sapiens	4-Chlorobenzaldehyde	1.7	3.066	0.5	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, 4-Chlorobenzaldehyde
AKR1A1	Homo sapiens	4-Nitrobenzaldehyde	6.95	0.191	37	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, 4-Nitrobenzaldehyde
AKR1A1	Homo sapiens	9,10-Phenanthrenequinone	0.83	0.152	5	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, 9,10-Phenanthrenequinone
AKR1A1	Homo sapiens	Pyridine-2-aldehyde	0.05	0.134	0.5	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, Pyridine-2-aldehyde
AKR1A1	Homo sapiens	Pyridine-3-aldehyde	6.18	0.597	10	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, Pyridine-3-aldehyde
AKR1A1	Homo sapiens	Pyridine-4-aldehyde	6.2	0.794	8.3	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, Pyridine-4-aldehyde
AKR1A1	Homo sapiens	Succinic semialdehyde	9.33	0.231	42	pH 7, 25 °C	PMID 10510318	Open record: AKR1A1, Succinic semialdehyde
AKR1A1 (aldehyde reductase)	Homo sapiens	(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienal (all-trans-farnesal)	—	0.06	3.3		PMID 19464995	Open record: AKR1A1 (aldehyde reductase), (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienal (all-trans-farnesal)
AKR1B1 (aldose reductase)	Homo sapiens	(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol (all-trans-farnesol)	0.032	0.083	0.33	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol (all-trans-farnesol)
AKR1B1 (aldose reductase)	Homo sapiens	(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienal (all-trans-farnesal)	0.45	0.037	12	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienal (all-trans-farnesal)
AKR1B1 (aldose reductase)	Homo sapiens	(R)-2-hydroxypropanal (D-lactaldehyde)	0.42	0.011	38	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), (R)-2-hydroxypropanal (D-lactaldehyde)
AKR1B1 (aldose reductase)	Homo sapiens	(S)-all-trans-4-hydroxyretinaldehyde	0.0967	—	—	pH 7.5, 25 °C	PMID 18087047	Open record: AKR1B1 (aldose reductase), (S)-all-trans-4-hydroxyretinaldehyde
AKR1B1 (aldose reductase)	Homo sapiens	1-Butanal	0.63	0.01	63	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), 1-Butanal
AKR1B1 (aldose reductase)	Homo sapiens	1-Decanol	0.016	0.026	0.67	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), 1-Decanol
AKR1B1 (aldose reductase)	Homo sapiens	1-Hexanol	0.04	0.98	0.033	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), 1-Hexanol
AKR1B1 (aldose reductase)	Homo sapiens	1-Nonanol	0.032	0.14	0.17	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), 1-Nonanol
AKR1B1 (aldose reductase)	Homo sapiens	2,3-Hexanedione	0.82	0.017	48	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), 2,3-Hexanedione
AKR1B1 (aldose reductase)	Homo sapiens	21-Dehydrocortisol	0.22	5 × 10⁻⁴	430	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), 21-Dehydrocortisol
AKR1B1 (aldose reductase)	Homo sapiens	9-cis-retinaldehyde	0.012	4 × 10⁻⁴	25	pH 7.4, 37 °C	PMID 18087047	Open record: AKR1B1 (aldose reductase), 9-cis-retinaldehyde
AKR1B1 (aldose reductase)	Homo sapiens	all-trans-retinaldehyde	0.0062	—	—	pH 7.5, 25 °C	PMID 18087047	Open record: AKR1B1 (aldose reductase), all-trans-retinaldehyde
AKR1B1 (aldose reductase)	Homo sapiens	Benzaldehyde	1.52	0.021	72	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), Benzaldehyde
AKR1B1 (aldose reductase)	Homo sapiens	Benzyl alcohol	0.017	0.61	0.033	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), Benzyl alcohol
AKR1B1 (aldose reductase)	Homo sapiens	D,L-glyceraldehyde	0.52	0.05	11	pH 7.4, 37 °C	PMID 18087047	Open record: AKR1B1 (aldose reductase), D,L-glyceraldehyde
AKR1B1 (aldose reductase)	Homo sapiens	d-glucose	0.55	80	0.0069 calc.	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), d-glucose
AKR1B1 (aldose reductase)	Homo sapiens	Geraniol	0.22	0.5	0.5	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), Geraniol
AKR1B1 (aldose reductase)	Homo sapiens	Glycolaldehyde	0.3	0.094	3.3	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), Glycolaldehyde
AKR1B1 (aldose reductase)	Homo sapiens	Glyoxal	0.87	0.36	1.7	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), Glyoxal
AKR1B1 (aldose reductase)	Homo sapiens	Isatin	0.22	0.015	15	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), Isatin
AKR1B1 (aldose reductase)	Homo sapiens	Nerol	0.0107	0.057	0.17	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), Nerol
AKR1B1 (aldose reductase)	Homo sapiens	pyridine-3-carbaldehyde	1.02	0.01	102	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), pyridine-3-carbaldehyde
AKR1B1 (aldose reductase)	Homo sapiens	trans-2-Buten-1-al	0.52	0.068	8.3	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), trans-2-Buten-1-al
AKR1B1 (aldose reductase)	Homo sapiens	trans-2-Decen-1-al	0.67	0.0084	80	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), trans-2-Decen-1-al
AKR1B1 (aldose reductase)	Homo sapiens	trans-2-Hexen-1-al	0.27	0.009	30	pH 7.4, 25 °C	PMID 19464995	Open record: AKR1B1 (aldose reductase), trans-2-Hexen-1-al
AKR1B1 (human aldose reductase)	Homo sapiens	all-trans-retinal	0.0058	0.0011	5.3	pH 7.4, 37 °C	PMID 16787387	Open record: AKR1B1 (human aldose reductase), all-trans-retinal
aldehyde reductase AKR1A4 (ALDR)	Mus musculus	1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine	0.0113	0.0111	1	pH 7, 37 °C	PMID 17381426	Open record: aldehyde reductase AKR1A4 (ALDR), 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine
aldehyde reductase AKR1A4 (ALDR)	Mus musculus	Methylglyoxal	7.63	1.1	7	pH 7, 25 °C	PMID 17381426	Open record: aldehyde reductase AKR1A4 (ALDR), Methylglyoxal
aldose reductase	Bos taurus (bovine)	2-deoxy-2-fluoro-D-glucose	0.05	12.5	0.0040 calc.	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 2-deoxy-2-fluoro-D-glucose
aldose reductase	Bos taurus (bovine)	2-deoxy-D-glucose	0.185	—	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 2-deoxy-D-glucose
aldose reductase	Bos taurus (bovine)	2-deoxy-D-glucoseapparent Km	—	10.4	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 2-deoxy-D-glucose
aldose reductase	Bos taurus (bovine)	2-deoxy-D-glucose	—	0.0759	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 2-deoxy-D-glucose
aldose reductase	Bos taurus (bovine)	2-deoxy-D-glucose	—	—	2.43	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 2-deoxy-D-glucose
aldose reductase	Bos taurus (bovine)	3-deoxy-3-fluoro-D-glucose	0.275	—	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 3-deoxy-3-fluoro-D-glucose
aldose reductase	Bos taurus (bovine)	3-deoxy-3-fluoro-D-glucoseapparent Km	—	0.31	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 3-deoxy-3-fluoro-D-glucose
aldose reductase	Bos taurus (bovine)	3-deoxy-3-fluoro-D-glucose	—	7.4 × 10⁻⁴	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 3-deoxy-3-fluoro-D-glucose
aldose reductase	Bos taurus (bovine)	3-deoxy-3-fluoro-D-glucose	—	—	372	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 3-deoxy-3-fluoro-D-glucose
aldose reductase	Bos taurus (bovine)	4-deoxy-4-fluoro-D-glucose	0.263	—	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 4-deoxy-4-fluoro-D-glucose
aldose reductase	Bos taurus (bovine)	4-deoxy-4-fluoro-D-glucoseapparent Km	—	0.54	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 4-deoxy-4-fluoro-D-glucose
aldose reductase	Bos taurus (bovine)	4-deoxy-4-fluoro-D-glucose	—	0.0039	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 4-deoxy-4-fluoro-D-glucose
aldose reductase	Bos taurus (bovine)	4-deoxy-4-fluoro-D-glucose	—	—	67.5	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 4-deoxy-4-fluoro-D-glucose
aldose reductase	Bos taurus (bovine)	5-thio-D-glucose	0.21	—	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 5-thio-D-glucose
aldose reductase	Bos taurus (bovine)	5-thio-D-glucoseapparent Km	—	6.3	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 5-thio-D-glucose
aldose reductase	Bos taurus (bovine)	5-thio-D-glucose	—	0.0315	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 5-thio-D-glucose
aldose reductase	Bos taurus (bovine)	5-thio-D-glucose	—	—	6.7	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 5-thio-D-glucose
aldose reductase	Bos taurus (bovine)	6-deoxy-6-fluoro-D-glucose	0.252	3.1	0.081 calc.	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 6-deoxy-6-fluoro-D-glucose
aldose reductase	Bos taurus (bovine)	6-deoxy-D-glucose	0.192	—	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 6-deoxy-D-glucose
aldose reductase	Bos taurus (bovine)	6-deoxy-D-glucoseapparent Km	—	9.8	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 6-deoxy-D-glucose
aldose reductase	Bos taurus (bovine)	6-deoxy-D-glucose	—	0.0196	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 6-deoxy-D-glucose
aldose reductase	Bos taurus (bovine)	6-deoxy-D-glucose	—	—	9.78	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, 6-deoxy-D-glucose
aldose reductase	Bos taurus (bovine)	D-glucose	0.252	—	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, D-glucose
aldose reductase	Bos taurus (bovine)	D-glucoseapparent Km	—	12.9	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, D-glucose
aldose reductase	Bos taurus (bovine)	D-glucose	—	0.0323	—	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, D-glucose
aldose reductase	Bos taurus (bovine)	D-glucose	—	—	7.78	pH 7.2, 27 °C	PMID 10209867	Open record: aldose reductase, D-glucose
aldose reductase (AKR1B1)	Homo sapiens	2,4-pentanedione	0.278	8.1	0.037	pH 7, 25 °C	PMID 26222439	Open record: aldose reductase (AKR1B1), 2,4-pentanedione
aldose reductase (AKR1B1)	Homo sapiens	3,5-heptanedione	0.43	12	0.037	pH 7, 25 °C	PMID 26222439	Open record: aldose reductase (AKR1B1), 3,5-heptanedione
aldose reductase (AKR1B1)	Homo sapiens	cinnamaldehyde	0.48	0.031	15.8	pH 7, 25 °C	PMID 26222439	Open record: aldose reductase (AKR1B1), cinnamaldehyde
aldose reductase (AKR1B1)	Homo sapiens	citral	1.13	0.035	29.2	pH 7, 25 °C	PMID 26222439	Open record: aldose reductase (AKR1B1), citral
aldose reductase (bAR)	Bos taurus	D-glucose	0.48	71.5	0.0068 calc.	pH 6.8, 37 °C	PMID 25528584	Open record: aldose reductase (bAR), D-glucose
aldose reductase (bAR)	Bos taurus	L-idose	0.5	0.8	0.62 calc.	pH 6.8, 37 °C	PMID 25528584	Open record: aldose reductase (bAR), L-idose
aldose reductase AKR1B1 (human AR)	Homo sapiens	1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine	0.432	0.0088	49	pH 7, 37 °C	PMID 17381426	Open record: aldose reductase AKR1B1 (human AR), 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine
aldose reductase AKR1B1 (human AR)	Homo sapiens	1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphoethanolamine	0.437	0.011	39.7	pH 7, 37 °C	PMID 17381426	Open record: aldose reductase AKR1B1 (human AR), 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphoethanolamine
aldose reductase AKR1B1 (human AR)	Homo sapiens	1-palmitoyl-2-(7-oxoheptanoyl)-sn-glycero-3-phosphocholine	0.408	0.0164	24.8	pH 7, 37 °C	PMID 17381426	Open record: aldose reductase AKR1B1 (human AR), 1-palmitoyl-2-(7-oxoheptanoyl)-sn-glycero-3-phosphocholine
aldose reductase AKR1B1 (human AR)	Homo sapiens	1-palmitoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine	0.402	0.0135	29.7	pH 7, 37 °C	PMID 17381426	Open record: aldose reductase AKR1B1 (human AR), 1-palmitoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine
aldose reductase AKR1B1 (human AR)	Homo sapiens	Glyceraldehyde	0.53	0.064	7.2	pH 7, 25 °C	PMID 17381426	Open record: aldose reductase AKR1B1 (human AR), Glyceraldehyde