Values CatLog read from this paper
The use of fluoro- and deoxy-substrate analogs to examine binding specificity and catalysis in the enzymes of the sorbitol pathway
PMID 10209867doi:10.1016/s0008-6215(98)00266-3Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 33 records (49 values) from this paper: aldose reductase, sorbitol dehydrogenase from Bos taurus (bovine), Ovis aries (sheep).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 2 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
EC 1.1.1.9, EC 1.1.1.14, EC 1.1.1.21, EC 1.1.1.54, EC 1.1.1.300, EC 1.1.1.372
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| aldose reductase | Bos taurus (bovine) | 2-deoxy-2-fluoro-D-glucose | 0.05 | 12.5 | 0.0040 calc. | pH 7.2, 27 °C | Open record: aldose reductase, 2-deoxy-2-fluoro-D-glucose |
| aldose reductase | Bos taurus (bovine) | 2-deoxy-D-glucose | 0.185 | — | — | pH 7.2, 27 °C | Open record: aldose reductase, 2-deoxy-D-glucose |
| aldose reductase | Bos taurus (bovine) | 2-deoxy-D-glucoseapparent Km | — | 10.4 | — | pH 7.2, 27 °C | Open record: aldose reductase, 2-deoxy-D-glucose |
| aldose reductase | Bos taurus (bovine) | 2-deoxy-D-glucose | — | 0.0759 | — | pH 7.2, 27 °C | Open record: aldose reductase, 2-deoxy-D-glucose |
| aldose reductase | Bos taurus (bovine) | 2-deoxy-D-glucose | — | — | 2.43 | pH 7.2, 27 °C | Open record: aldose reductase, 2-deoxy-D-glucose |
| aldose reductase | Bos taurus (bovine) | 3-deoxy-3-fluoro-D-glucose | 0.275 | — | — | pH 7.2, 27 °C | Open record: aldose reductase, 3-deoxy-3-fluoro-D-glucose |
| aldose reductase | Bos taurus (bovine) | 3-deoxy-3-fluoro-D-glucoseapparent Km | — | 0.31 | — | pH 7.2, 27 °C | Open record: aldose reductase, 3-deoxy-3-fluoro-D-glucose |
| aldose reductase | Bos taurus (bovine) | 3-deoxy-3-fluoro-D-glucose | — | 7.4 × 10⁻⁴ | — | pH 7.2, 27 °C | Open record: aldose reductase, 3-deoxy-3-fluoro-D-glucose |
| aldose reductase | Bos taurus (bovine) | 3-deoxy-3-fluoro-D-glucose | — | — | 372 | pH 7.2, 27 °C | Open record: aldose reductase, 3-deoxy-3-fluoro-D-glucose |
| aldose reductase | Bos taurus (bovine) | 4-deoxy-4-fluoro-D-glucose | 0.263 | — | — | pH 7.2, 27 °C | Open record: aldose reductase, 4-deoxy-4-fluoro-D-glucose |
| aldose reductase | Bos taurus (bovine) | 4-deoxy-4-fluoro-D-glucoseapparent Km | — | 0.54 | — | pH 7.2, 27 °C | Open record: aldose reductase, 4-deoxy-4-fluoro-D-glucose |
| aldose reductase | Bos taurus (bovine) | 4-deoxy-4-fluoro-D-glucose | — | 0.0039 | — | pH 7.2, 27 °C | Open record: aldose reductase, 4-deoxy-4-fluoro-D-glucose |
| aldose reductase | Bos taurus (bovine) | 4-deoxy-4-fluoro-D-glucose | — | — | 67.5 | pH 7.2, 27 °C | Open record: aldose reductase, 4-deoxy-4-fluoro-D-glucose |
| aldose reductase | Bos taurus (bovine) | 5-thio-D-glucose | 0.21 | — | — | pH 7.2, 27 °C | Open record: aldose reductase, 5-thio-D-glucose |
| aldose reductase | Bos taurus (bovine) | 5-thio-D-glucoseapparent Km | — | 6.3 | — | pH 7.2, 27 °C | Open record: aldose reductase, 5-thio-D-glucose |
| aldose reductase | Bos taurus (bovine) | 5-thio-D-glucose | — | 0.0315 | — | pH 7.2, 27 °C | Open record: aldose reductase, 5-thio-D-glucose |
| aldose reductase | Bos taurus (bovine) | 5-thio-D-glucose | — | — | 6.7 | pH 7.2, 27 °C | Open record: aldose reductase, 5-thio-D-glucose |
| aldose reductase | Bos taurus (bovine) | 6-deoxy-6-fluoro-D-glucose | 0.252 | 3.1 | 0.081 calc. | pH 7.2, 27 °C | Open record: aldose reductase, 6-deoxy-6-fluoro-D-glucose |
| aldose reductase | Bos taurus (bovine) | 6-deoxy-D-glucose | 0.192 | — | — | pH 7.2, 27 °C | Open record: aldose reductase, 6-deoxy-D-glucose |
| aldose reductase | Bos taurus (bovine) | 6-deoxy-D-glucoseapparent Km | — | 9.8 | — | pH 7.2, 27 °C | Open record: aldose reductase, 6-deoxy-D-glucose |
| aldose reductase | Bos taurus (bovine) | 6-deoxy-D-glucose | — | 0.0196 | — | pH 7.2, 27 °C | Open record: aldose reductase, 6-deoxy-D-glucose |
| aldose reductase | Bos taurus (bovine) | 6-deoxy-D-glucose | — | — | 9.78 | pH 7.2, 27 °C | Open record: aldose reductase, 6-deoxy-D-glucose |
| aldose reductase | Bos taurus (bovine) | D-glucose | 0.252 | — | — | pH 7.2, 27 °C | Open record: aldose reductase, D-glucose |
| aldose reductase | Bos taurus (bovine) | D-glucoseapparent Km | — | 12.9 | — | pH 7.2, 27 °C | Open record: aldose reductase, D-glucose |
| aldose reductase | Bos taurus (bovine) | D-glucose | — | 0.0323 | — | pH 7.2, 27 °C | Open record: aldose reductase, D-glucose |
| aldose reductase | Bos taurus (bovine) | D-glucose | — | — | 7.78 | pH 7.2, 27 °C | Open record: aldose reductase, D-glucose |
| sorbitol dehydrogenase | Ovis aries (sheep) | 3-deoxy-3-fluoro-D-glucitol | 5.83 | 15.5 | 0.377 | pH 8, 30 °C | Open record: sorbitol dehydrogenase, 3-deoxy-3-fluoro-D-glucitol |
| sorbitol dehydrogenase | Ovis aries (sheep) | 3-deoxy-D-glucitol | 7.35 | 1.9 | 3.85 | pH 8, 30 °C | Open record: sorbitol dehydrogenase, 3-deoxy-D-glucitol |
| sorbitol dehydrogenase | Ovis aries (sheep) | 4-deoxy-4-fluoro-D-glucitol | 5.9 | 11.7 | 0.505 | pH 8, 30 °C | Open record: sorbitol dehydrogenase, 4-deoxy-4-fluoro-D-glucitol |
| sorbitol dehydrogenase | Ovis aries (sheep) | 4-deoxy-D-glucitol | 2.15 | 26.4 | 0.082 | pH 8, 30 °C | Open record: sorbitol dehydrogenase, 4-deoxy-D-glucitol |
| sorbitol dehydrogenase | Ovis aries (sheep) | 6-deoxy-6-fluoro-D-glucitol | 9.32 | 0.74 | 12.58 | pH 8, 30 °C | Open record: sorbitol dehydrogenase, 6-deoxy-6-fluoro-D-glucitol |
| sorbitol dehydrogenase | Ovis aries (sheep) | 6-deoxy-D-glucitol | 4.57 | 0.48 | 11.42 | pH 8, 30 °C | Open record: sorbitol dehydrogenase, 6-deoxy-D-glucitol |
| sorbitol dehydrogenase | Ovis aries (sheep) | D-glucitol | 8.43 | 1.5 | 5.62 | pH 8, 30 °C | Open record: sorbitol dehydrogenase, D-glucitol |