CatLogenzyme kinetics catalog

Values CatLog read from this paper

The catalytic inactivation of the N-half of human hexokinase 2 and structural and biochemical characterization of its mitochondrial conformation

PMID 29298880doi:10.1042/bsr20171666Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 20 records (50 values) from this paper: hexokinase 2 (HK2) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.7.1.1

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
hexokinase 2 (HK2)Homo sapiensATP—1.1349pH 7.5, 25 °COpen
hexokinase 2 (HK2)Homo sapiensATPΔ16-HK2: residues 17-916—0.47148pH 7.5, 25 °COpen
hexokinase 2 (HK2)Homo sapiensATPseparate N-terminal domain—0.7613pH 7.5, 25 °COpen
hexokinase 2 (HK2)Homo sapiensATPseparate N-terminal domain (FL-N-term)—0.4838pH 7.5, 25 °COpen
hexokinase 2 (HK2)Homo sapiensATPseparate N-terminal domain lacking the MBP (Δ16-N-term)—0.25180pH 7.5, 25 °COpen
hexokinase 2 (HK2)Homo sapiensATPseparate C-terminal domain (C-term); residues 465-916—1.76.1pH 7.5, 25 °COpen
hexokinase 2 (HK2)Homo sapiensglucose55.40.21264pH 7.5, 25 °COpen
hexokinase 2 (HK2)Homo sapiensglucoseΔ16-HK2: residues 17-91669.70.17410pH 7.5, 25 °COpen
hexokinase 2 (HK2)Homo sapiensglucoseseparate N-terminal domain10.20.2442pH 7.5, 25 °COpen
hexokinase 2 (HK2)Homo sapiensglucoseseparate N-terminal domain (FL-N-term)18.10.3257pH 7.5, 25 °COpen
hexokinase 2 (HK2)Homo sapiensglucoseseparate N-terminal domain lacking the MBP (Δ16-N-term)45.50.18251pH 7.5, 25 °COpen
hexokinase 2 (HK2)Homo sapiensglucoseseparate C-terminal domain (C-term); residues 465-91610.40.1955pH 7.5, 25 °COpen
hexokinase 2 (HK2)variant D209AHomo sapiensATP—0.847pH 7.5, 25 °COpen
hexokinase 2 (HK2)variant D209AHomo sapiensATPΔ16-HK2: residues 17-916—0.43172pH 7.5, 25 °COpen
hexokinase 2 (HK2)variant D209AHomo sapiensglucose37.50.18208pH 7.5, 25 °COpen
hexokinase 2 (HK2)variant D209AHomo sapiensglucoseΔ16-HK2: residues 17-91673.20.26289pH 7.5, 25 °COpen
hexokinase 2 (HK2)variant D657AHomo sapiensATP—1.0453pH 7.5, 25 °COpen
hexokinase 2 (HK2)variant D657AHomo sapiensATPΔ16-HK2: residues 17-916—0.3770pH 7.5, 25 °COpen
hexokinase 2 (HK2)variant D657AHomo sapiensglucose550.26212pH 7.5, 25 °COpen
hexokinase 2 (HK2)variant D657AHomo sapiensglucoseΔ16-HK2: residues 17-91625.90.16164pH 7.5, 25 °COpen