Values CatLog read from this paper
Kinetic characterization of cholinesterases and a therapeutically valuable cocaine hydrolase for their catalytic activities against heroin and its metabolite 6-monoacetylmorphine
PMID 30080993doi:10.1016/j.cbi.2018.08.002Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (18 values) from this paper: AChE (acetylcholinesterase), BChE (butyrylcholinesterase), CocH1 (cocaine hydrolase derived from human BChE) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| AChE (acetylcholinesterase) | Homo sapiens | 3,6-diacetylmorphine | 35 | 2.17 | 16.13 | pH 7.4, 37 °C | Open record: AChE (acetylcholinesterase), 3,6-diacetylmorphine |
| AChE (acetylcholinesterase) | Homo sapiens | 6-monoacetylmorphine | 0.118 | 0.259 | 0.455 | pH 7.4, 37 °C | Open record: AChE (acetylcholinesterase), 6-monoacetylmorphine |
| BChE (butyrylcholinesterase) | Homo sapiens | 3,6-diacetylmorphine | 30.67 | 0.12 | 255 | pH 7.4, 37 °C | Open record: BChE (butyrylcholinesterase), 3,6-diacetylmorphine |
| BChE (butyrylcholinesterase) | Homo sapiens | 6-monoacetylmorphine | 0.00108 | 0.024 | 0.0452 | pH 7.4, 37 °C | Open record: BChE (butyrylcholinesterase), 6-monoacetylmorphine |
| CocH1 (cocaine hydrolase derived from human BChE)variant A199S/F227A/S287G/A328W | Homo sapiens | 3,6-diacetylmorphine | 35.83 | 0.245 | 146.3 | pH 7.4, 37 °C | Open record: CocH1 (cocaine hydrolase derived from human BChE) variant A199S/F227A/S287G/A328W, 3,6-diacetylmorphine |
| CocH1 (cocaine hydrolase derived from human BChE)variant A199S/F227A/S287G/A328W | Homo sapiens | 6-monoacetylmorphine | 0.00372 | 0.292 | 0.01273 | pH 7.4, 37 °C | Open record: CocH1 (cocaine hydrolase derived from human BChE) variant A199S/F227A/S287G/A328W, 6-monoacetylmorphine |