CatLogenzyme kinetics catalog

Values CatLog read from this paper

Catalytic and inhibitor-binding properties of some active-site mutants of human carbonic anhydrase I

PMID 7758465doi:10.1111/j.1432-1033.1995.0696j.xOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 26 records (64 values) from this paper: carbonic anhydrase I (HCA I) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 4.2.1.1

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
carbonic anhydrase I (HCA I)Homo sapiens4-nitrophenyl acetate——0.8125 °COpen
carbonic anhydrase I (HCA I)Homo sapienscarbon dioxide2.1 × 10⁵5.33.9 × 10⁴pH 8.77, 25 °COpen
carbonic anhydrase I (HCA I)Homo sapienscarbon dioxide4.8 × 10⁴3.61.3 × 10⁴pH 7.21, 25 °COpen
carbonic anhydrase I (HCA I)variant H200THomo sapiens4-nitrophenyl acetate——0.08825 °COpen
carbonic anhydrase I (HCA I)variant H200THomo sapienscarbon dioxide3.3 × 10⁵103.3 × 10⁴pH 8.95, 25 °COpen
carbonic anhydrase I (HCA I)variant H200THomo sapienscarbon dioxide1.4 × 10⁵43.4 × 10⁴pH 8.92, 25 °COpen
carbonic anhydrase I (HCA I)variant H200THomo sapienscarbon dioxide1.4 × 10⁴0.314.7 × 10⁴pH 8.88, 25 °COpen
carbonic anhydrase I (HCA I)variant H200THomo sapienscarbon dioxide8.3 × 10⁴2.43.4 × 10⁴pH 7.21, 25 °COpen
carbonic anhydrase I (HCA I)variant H200THomo sapienscarbon dioxide1.3 × 10⁴——pH 6.3, 25 °COpen
carbonic anhydrase I (HCA I)variant H67NHomo sapiens4-nitrophenyl acetate——1.225 °COpen
carbonic anhydrase I (HCA I)variant H67NHomo sapienscarbon dioxide1.7 × 10⁵6.62.5 × 10⁴pH 8.75, 25 °COpen
carbonic anhydrase I (HCA I)variant H67NHomo sapienscarbon dioxide7.1 × 10⁴2.42.9 × 10⁴pH 8.98, 25 °COpen
carbonic anhydrase I (HCA I)variant H67NHomo sapienscarbon dioxide5.3 × 10⁴153.6 × 10³pH 7.23, 25 °COpen
carbonic anhydrase I (HCA I)variant H67NHomo sapienscarbon dioxide1.5 × 10⁴46320pH 6.28, 25 °COpen
carbonic anhydrase I (HCA I)variant V62NHomo sapiens4-nitrophenyl acetate——1.125 °COpen
carbonic anhydrase I (HCA I)variant V62NHomo sapienscarbon dioxide1.2 × 10⁵7.11.7 × 10⁴pH 8.95, 25 °COpen
carbonic anhydrase I (HCA I)variant V62NHomo sapienscarbon dioxide7.1 × 10⁴3.52.1 × 10⁴pH 8.98, 25 °COpen
carbonic anhydrase I (HCA I)variant V62NHomo sapienscarbon dioxide1.3 × 10⁴69190pH 6.28, 25 °COpen
carbonic anhydrase I (HCA I)variant V62N/H67NHomo sapiens4-nitrophenyl acetate——1.325 °COpen
carbonic anhydrase I (HCA I)variant V62N/H67NHomo sapienscarbon dioxide2.1 × 10⁵9.42.2 × 10⁴pH 8.72, 25 °COpen
carbonic anhydrase I (HCA I)variant V62N/H67NHomo sapienscarbon dioxide8.8 × 10⁴42.2 × 10⁴pH 8.88, 25 °COpen
carbonic anhydrase I (HCA I)variant V62N/H67N/H200THomo sapiens4-nitrophenyl acetate——0.4925 °COpen
carbonic anhydrase I (HCA I)variant V62N/H67N/H200THomo sapienscarbon dioxide5.1 × 10⁵143.4 × 10⁴pH 8.75, 25 °COpen
carbonic anhydrase I (HCA I)variant V62N/H67N/H200THomo sapienscarbon dioxide8.4 × 10⁴2.33.7 × 10⁴pH 8.98, 25 °COpen
carbonic anhydrase I (HCA I)variant V62N/H67N/H200THomo sapienscarbon dioxide2.2 × 10⁵7.52.9 × 10⁴pH 7.23, 25 °COpen
carbonic anhydrase I (HCA I)variant V62N/H67N/H200THomo sapienscarbon dioxide5.1 × 10³3.61.4 × 10³pH 6.28, 25 °COpen