EC 4.2.1.1: carbonic anhydrase

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CatLog read 137 records for EC 4.2.1.1 from 9 papers, for 7 organisms. Names in these papers: Cam (gamma-class carbonic anhydrase), carbonic anhydrase, carbonic anhydrase I (HCA I), carbonic anhydrase Cam (gamma-class) and 5 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 683 records for EC 4.2.1.1 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.2.1.1 in Browse.

Papers

Papers with records for EC 4.2.1.1
Paper	Organisms	Records
Role of arginine 59 in the gamma-class carbonic anhydrases	Methanosarcina thermophila	34
Plant carbonic anhydrase. Properties and carbon dioxide hydration kinetics	Spinacia oleracea	26
Catalytic and inhibitor-binding properties of some active-site mutants of human carbonic anhydrase I	Homo sapiens	26
Role of Trp19 and Tyr200 in catalysis by the γ-class carbonic anhydrase from Methanosarcina thermophila	Methanosarcina thermophila	19
Roles of the conserved aspartate and arginine in the catalytic mechanism of an archaeal beta-class carbonic anhydrase	Methanobacterium thermoautotrophicum	14
Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes	Homo sapiens	8
A Selective Phenyl Azo Acetate Substrate for Enhanced Carbonic Anhydrase Functional Analysis	Bos taurus	6
The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines	Sulfurihydrogenibium azorense	2
From Identification to Enzymatic Activity Profiling: Comprehensive Characterization of BloCAβ, a Probiotic β-Carbonic Anhydrase From Bifidobacterium longum	Bifidobacterium longum	2

Records

Records for EC 4.2.1.1 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
BloCAβ (β-class carbonic anhydrase)	Bifidobacterium longum	carbon dioxideTable 2	2.43 × 10⁵	—	1.45 × 10⁴	pH 8.3, 20 °C	PMID 42745684	Open record: BloCAβ (β-class carbonic anhydrase), carbon dioxide
BloCAβ (β-class carbonic anhydrase)	Bifidobacterium longum	carbon dioxidein the text	—	16.8	—	pH 8.3, 20 °C	PMID 42745684	Open record: BloCAβ (β-class carbonic anhydrase), carbon dioxide
Cab (beta-class carbonic anhydrase)	Methanobacterium thermoautotrophicum	carbon dioxide	2.4 × 10⁴	2.9	8.3 × 10³	pH 8.5, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase), carbon dioxide
Cab (beta-class carbonic anhydrase)	Methanobacterium thermoautotrophicum	carbon dioxide50 mM MOPS buffer	1.1 × 10⁴	2.7	4.1 × 10³	pH 7.2, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase), carbon dioxide
Cab (beta-class carbonic anhydrase)	Methanobacterium thermoautotrophicum	carbon dioxide50 mM imidazole buffer	1.3 × 10⁴	4.2	3.2 × 10³	pH 7.2, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase), carbon dioxide
Cab (beta-class carbonic anhydrase)variant D34A	Methanobacterium thermoautotrophicum	carbon dioxide	4.2 × 10³	3.6	1.2 × 10³	pH 8.5, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase) variant D34A, carbon dioxide
Cab (beta-class carbonic anhydrase)variant D34A	Methanobacterium thermoautotrophicum	carbon dioxide50 mM MOPS buffer	1.1 × 10³	3.5	2.9 × 10³	pH 7.2, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase) variant D34A, carbon dioxide
Cab (beta-class carbonic anhydrase)variant D34A	Methanobacterium thermoautotrophicum	carbon dioxide50 mM imidazole buffer	9.1 × 10³	15.3	600	pH 7.2, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase) variant D34A, carbon dioxide
Cab (beta-class carbonic anhydrase)variant D34A/R36A	Methanobacterium thermoautotrophicum	carbon dioxide	520	9.2	560	pH 8.5, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase) variant D34A/R36A, carbon dioxide
Cab (beta-class carbonic anhydrase)variant D34A/R36A	Methanobacterium thermoautotrophicum	carbon dioxide50 mM MOPS buffer	260	9.2	29	pH 7.2, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase) variant D34A/R36A, carbon dioxide
Cab (beta-class carbonic anhydrase)variant D34A/R36A	Methanobacterium thermoautotrophicum	carbon dioxide50 mM imidazole buffer	1.5 × 10³	5.8	260	pH 7.2, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase) variant D34A/R36A, carbon dioxide
Cab (beta-class carbonic anhydrase)variant D34E	Methanobacterium thermoautotrophicum	carbon dioxide	3.6 × 10³	1.8	2 × 10³	pH 8.5, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase) variant D34E, carbon dioxide
Cab (beta-class carbonic anhydrase)variant R36A	Methanobacterium thermoautotrophicum	carbon dioxide	46	36.2	1.3	pH 8.5, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase) variant R36A, carbon dioxide
Cab (beta-class carbonic anhydrase)variant R36A	Methanobacterium thermoautotrophicum	carbon dioxide50 mM MOPS buffer	24	35.3	0.67	pH 7.2, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase) variant R36A, carbon dioxide
Cab (beta-class carbonic anhydrase)variant R36A	Methanobacterium thermoautotrophicum	carbon dioxide50 mM imidazole buffer	30	47.1	0.64	pH 7.2, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase) variant R36A, carbon dioxide
Cab (beta-class carbonic anhydrase)variant R36K	Methanobacterium thermoautotrophicum	carbon dioxide	92	7.2	13	pH 8.5, 25 °C	PMID 12107142	Open record: Cab (beta-class carbonic anhydrase) variant R36K, carbon dioxide
Cam (gamma-class carbonic anhydrase)	Methanosarcina thermophila	carbon dioxideno GdnHCl	6.29 × 10⁴	21.8	2.89 × 10³	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase), carbon dioxide
Cam (gamma-class carbonic anhydrase)	Methanosarcina thermophila	carbon dioxide100 mM guanidine hydrochloride (GdnHCl) as rescue agent	2.92 × 10⁴	16.7	1.75 × 10³	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase), carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxideno GdnHCl	70	15.7	4.5	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide100 mM guanidine hydrochloride (GdnHCl) as rescue agent	3.27 × 10³	17.1	192	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide50 mM guanidine hydrochloride as rescue agent	2.71 × 10³	14.5	187	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide150 mM guanidine hydrochloride as rescue agent	2.25 × 10³	11.7	193	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide100 mM methylguanidine (chloride salt) as rescue agent	5.69 × 10³	12.2	468	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide100 mM ethylguanidine (sulfate salt) as rescue agent	7.14 × 10³	16.2	441	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide100 mM aminoguanidine as rescue agent	350	9.45	37	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide100 mM ethylamine as rescue agent	160	25.4	6.4	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide100 mM imidazole as rescue agent	110	34	3.1	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide100 mM urea as rescue agent	28	26.2	1.1	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide100 mM 1,3-diaminoguanidine as rescue agent	12	12.8	1	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide	1.7 × 10³	—	—		PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide	—	—	67		PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59A	Methanosarcina thermophila	carbon dioxide	—	—	860		PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59A, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59C	Methanosarcina thermophila	carbon dioxideno GdnHCl	520	34.2	15	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59C, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59C	Methanosarcina thermophila	carbon dioxide100 mM guanidine hydrochloride (GdnHCl) as rescue agent	2.17 × 10³	13.6	159	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59C, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59C	Methanosarcina thermophila	carbon dioxide100 mM methylguanidine (chloride salt) as rescue agent	990	17.3	57	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59C, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59C	Methanosarcina thermophila	carbon dioxide100 mM ethylguanidine (sulfate salt) as rescue agent	310	6.5	48	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59C, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59C	Methanosarcina thermophila	carbon dioxide100 mM aminoguanidine as rescue agent	320	47.6	6.8	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59C, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59E	Methanosarcina thermophila	carbon dioxideno GdnHCl	19	51.4	0.4	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59E, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59E	Methanosarcina thermophila	carbon dioxide100 mM guanidine hydrochloride (GdnHCl) as rescue agent	67	19.3	3.5	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59E, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59H	Methanosarcina thermophila	carbon dioxideno GdnHCl	42	25	1.7	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59H, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59H	Methanosarcina thermophila	carbon dioxide100 mM guanidine hydrochloride (GdnHCl) as rescue agent	12	6.09	2	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59H, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59K	Methanosarcina thermophila	carbon dioxideno GdnHCl	4.72 × 10³	33.4	141	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59K, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59K	Methanosarcina thermophila	carbon dioxide100 mM guanidine hydrochloride (GdnHCl) as rescue agent	2.74 × 10³	19.1	143	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59K, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59K	Methanosarcina thermophila	carbon dioxide	4.8 × 10³	—	—		PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59K, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59K	Methanosarcina thermophila	carbon dioxide	—	—	130		PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59K, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59K	Methanosarcina thermophila	carbon dioxide	—	—	1.73 × 10³		PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59K, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59M	Methanosarcina thermophila	carbon dioxideno GdnHCl	13	43.3	0.3	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59M, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59M	Methanosarcina thermophila	carbon dioxide100 mM guanidine hydrochloride (GdnHCl) as rescue agent	159	16.3	9.8	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59M, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59Q	Methanosarcina thermophila	carbon dioxideno GdnHCl	10	33.9	0.3	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59Q, carbon dioxide
Cam (gamma-class carbonic anhydrase)variant R59Q	Methanosarcina thermophila	carbon dioxide100 mM guanidine hydrochloride (GdnHCl) as rescue agent	627	17.3	36.3	pH 7.5	PMID 11781108	Open record: Cam (gamma-class carbonic anhydrase) variant R59Q, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	5.8 × 10⁴	17.9	3.2 × 10³ calc.	pH 6.25, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	5.9 × 10⁴	9.3	6.3 × 10³ calc.	pH 6.46, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	8.3 × 10⁴	7.6	1.1 × 10⁴ calc.	pH 6.67, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	7.7 × 10⁴	3.7	2.1 × 10⁴ calc.	pH 6.87, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	1.09 × 10⁵	4.1	2.7 × 10⁴ calc.	pH 7, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	1.35 × 10⁵	1.6	8.4 × 10⁴ calc.	pH 7.25, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	1.69 × 10⁵	1.8	9.4 × 10⁴ calc.	pH 7.43, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	2.86 × 10⁵	2.4	1.2 × 10⁵ calc.	pH 7.76, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	3.86 × 10⁵	2.1	1.8 × 10⁵ calc.	pH 7.96, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	3.84 × 10⁵	1	3.8 × 10⁵ calc.	pH 8.17, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	4.37 × 10⁵	1	4.4 × 10⁵ calc.	pH 8.39, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	4.26 × 10⁵	1.7	2.5 × 10⁵ calc.	pH 8.7, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	4.77 × 10⁵	1.5	3.2 × 10⁵ calc.	pH 8.88, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	5.32 × 10⁵	1.2	4.4 × 10⁵ calc.	pH 9.03, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxidetotal buffer 2.5 × 10^-2 M	1.05 × 10⁵	24.4	4.30 × 10³ calc.	pH 6.26, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxidetotal buffer 2.0 × 10^-2 M	8.7 × 10⁴	17.1	5.1 × 10³ calc.	pH 6.26, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxidetotal buffer 1.25 × 10^-2 M	4.5 × 10⁴	10.6	4.2 × 10³ calc.	pH 6.26, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxidetotal buffer 2.0 × 10^-2 M	1.12 × 10⁵	8.7	1.3 × 10⁴ calc.	pH 6.62, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxidetotal buffer 1.25 × 10^-2 M	6.1 × 10⁴	5.5	1.1 × 10⁴ calc.	pH 6.62, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxidetotal buffer 2.5 × 10^-2 M	7.1 × 10⁴	12.1	5.9 × 10³ calc.	pH 6.74, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxidetotal buffer 1.5 × 10^-2 M	6.2 × 10⁴	7.9	7.8 × 10³ calc.	pH 6.74, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxidetotal buffer 2.5 × 10^-2 M	1 × 10⁵	7.8	1.3 × 10⁴ calc.	pH 7.11, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxidetotal buffer 2.0 × 10^-2 M	9.4 × 10⁴	4.8	2.0 × 10⁴ calc.	pH 7.11, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxidetotal buffer 1.5 × 10^-2 M	8.5 × 10⁴	3.9	2.2 × 10⁴ calc.	pH 7.11, 25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxide	—	1.5	—	25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase	Spinacia oleracea	carbon dioxidehigh-activity plateau of the k2-pH profile (pH ~9)	4.7 × 10⁵	—	—	25 °C	PMID 4210017	Open record: carbonic anhydrase, carbon dioxide
carbonic anhydrase Cam (gamma-class)	Methanosarcina thermophila	carbon dioxide	3.24 × 10⁴	—	2 × 10³	pH 7.5	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class), carbon dioxide
carbonic anhydrase Cam (gamma-class)	Methanosarcina thermophila	carbon dioxide	2.94 × 10⁴	—	3.1 × 10³	pH 8.8	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class), carbon dioxide
carbonic anhydrase Cam (gamma-class)	Methanosarcina thermophila	carbon dioxide	—	—	1.4 × 10⁴	25 °C	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class), carbon dioxide
carbonic anhydrase Cam (gamma-class)variant W19A	Methanosarcina thermophila	carbon dioxide	7.9 × 10³	—	790	pH 7.5	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant W19A, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant W19A	Methanosarcina thermophila	carbon dioxide	8.5 × 10³	—	1.4 × 10³	pH 8.8	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant W19A, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant W19F	Methanosarcina thermophila	carbon dioxide	6.5 × 10³	—	400	pH 7.5	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant W19F, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant W19F	Methanosarcina thermophila	carbon dioxide	9.5 × 10³	—	600	pH 8.8	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant W19F, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant W19F	Methanosarcina thermophila	carbon dioxide	—	—	900	25 °C	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant W19F, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant W19N	Methanosarcina thermophila	carbon dioxide	5.8 × 10³	—	630	pH 7.5	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant W19N, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant W19N	Methanosarcina thermophila	carbon dioxide	5.2 × 10³	—	1.3 × 10³	pH 8.8	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant W19N, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant W19N	Methanosarcina thermophila	carbon dioxide	—	—	1.2 × 10³	25 °C	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant W19N, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant Y200A	Methanosarcina thermophila	carbon dioxide	9.5 × 10⁴	—	7 × 10³	pH 7.5	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant Y200A, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant Y200A	Methanosarcina thermophila	carbon dioxide	8.85 × 10⁴	—	1.03 × 10⁴	pH 8.8	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant Y200A, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant Y200A	Methanosarcina thermophila	carbon dioxide	—	—	4 × 10³	25 °C	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant Y200A, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant Y200F	Methanosarcina thermophila	carbon dioxide	1.201 × 10⁵	—	7.1 × 10³	pH 7.5	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant Y200F, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant Y200F	Methanosarcina thermophila	carbon dioxide	1.536 × 10⁵	—	7.9 × 10³	pH 8.8	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant Y200F, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant Y200F	Methanosarcina thermophila	carbon dioxide	—	—	3.7 × 10³	25 °C	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant Y200F, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant Y200S	Methanosarcina thermophila	carbon dioxide	7.93 × 10⁴	—	5.9 × 10³	pH 7.5	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant Y200S, carbon dioxide
carbonic anhydrase Cam (gamma-class)variant Y200S	Methanosarcina thermophila	carbon dioxide	6.88 × 10⁴	—	1.02 × 10⁴	pH 8.8	PMID 23111186	Open record: carbonic anhydrase Cam (gamma-class) variant Y200S, carbon dioxide
carbonic anhydrase I (HCA I)	Homo sapiens	4-nitrophenyl acetate	—	—	0.81	25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I), 4-nitrophenyl acetate
carbonic anhydrase I (HCA I)	Homo sapiens	carbon dioxide	2.1 × 10⁵	5.3	3.9 × 10⁴	pH 8.77, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I), carbon dioxide
carbonic anhydrase I (HCA I)	Homo sapiens	carbon dioxide	4.8 × 10⁴	3.6	1.3 × 10⁴	pH 7.21, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I), carbon dioxide
carbonic anhydrase I (HCA I)variant H200T	Homo sapiens	4-nitrophenyl acetate	—	—	0.088	25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant H200T, 4-nitrophenyl acetate
carbonic anhydrase I (HCA I)variant H200T	Homo sapiens	carbon dioxide	3.3 × 10⁵	10	3.3 × 10⁴	pH 8.95, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant H200T, carbon dioxide
carbonic anhydrase I (HCA I)variant H200T	Homo sapiens	carbon dioxide	1.4 × 10⁵	4	3.4 × 10⁴	pH 8.92, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant H200T, carbon dioxide
carbonic anhydrase I (HCA I)variant H200T	Homo sapiens	carbon dioxide	1.4 × 10⁴	0.31	4.7 × 10⁴	pH 8.88, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant H200T, carbon dioxide
carbonic anhydrase I (HCA I)variant H200T	Homo sapiens	carbon dioxide	8.3 × 10⁴	2.4	3.4 × 10⁴	pH 7.21, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant H200T, carbon dioxide
carbonic anhydrase I (HCA I)variant H200T	Homo sapiens	carbon dioxide	1.3 × 10⁴	—	—	pH 6.3, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant H200T, carbon dioxide
carbonic anhydrase I (HCA I)variant H67N	Homo sapiens	4-nitrophenyl acetate	—	—	1.2	25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant H67N, 4-nitrophenyl acetate
carbonic anhydrase I (HCA I)variant H67N	Homo sapiens	carbon dioxide	1.7 × 10⁵	6.6	2.5 × 10⁴	pH 8.75, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant H67N, carbon dioxide
carbonic anhydrase I (HCA I)variant H67N	Homo sapiens	carbon dioxide	7.1 × 10⁴	2.4	2.9 × 10⁴	pH 8.98, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant H67N, carbon dioxide
carbonic anhydrase I (HCA I)variant H67N	Homo sapiens	carbon dioxide	5.3 × 10⁴	15	3.6 × 10³	pH 7.23, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant H67N, carbon dioxide
carbonic anhydrase I (HCA I)variant H67N	Homo sapiens	carbon dioxide	1.5 × 10⁴	46	320	pH 6.28, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant H67N, carbon dioxide
carbonic anhydrase I (HCA I)variant V62N	Homo sapiens	4-nitrophenyl acetate	—	—	1.1	25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant V62N, 4-nitrophenyl acetate
carbonic anhydrase I (HCA I)variant V62N	Homo sapiens	carbon dioxide	1.2 × 10⁵	7.1	1.7 × 10⁴	pH 8.95, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant V62N, carbon dioxide
carbonic anhydrase I (HCA I)variant V62N	Homo sapiens	carbon dioxide	7.1 × 10⁴	3.5	2.1 × 10⁴	pH 8.98, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant V62N, carbon dioxide
carbonic anhydrase I (HCA I)variant V62N	Homo sapiens	carbon dioxide	1.3 × 10⁴	69	190	pH 6.28, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant V62N, carbon dioxide
carbonic anhydrase I (HCA I)variant V62N/H67N	Homo sapiens	4-nitrophenyl acetate	—	—	1.3	25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant V62N/H67N, 4-nitrophenyl acetate
carbonic anhydrase I (HCA I)variant V62N/H67N	Homo sapiens	carbon dioxide	2.1 × 10⁵	9.4	2.2 × 10⁴	pH 8.72, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant V62N/H67N, carbon dioxide
carbonic anhydrase I (HCA I)variant V62N/H67N	Homo sapiens	carbon dioxide	8.8 × 10⁴	4	2.2 × 10⁴	pH 8.88, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant V62N/H67N, carbon dioxide
carbonic anhydrase I (HCA I)variant V62N/H67N/H200T	Homo sapiens	4-nitrophenyl acetate	—	—	0.49	25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant V62N/H67N/H200T, 4-nitrophenyl acetate
carbonic anhydrase I (HCA I)variant V62N/H67N/H200T	Homo sapiens	carbon dioxide	5.1 × 10⁵	14	3.4 × 10⁴	pH 8.75, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant V62N/H67N/H200T, carbon dioxide
carbonic anhydrase I (HCA I)variant V62N/H67N/H200T	Homo sapiens	carbon dioxide	8.4 × 10⁴	2.3	3.7 × 10⁴	pH 8.98, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant V62N/H67N/H200T, carbon dioxide
carbonic anhydrase I (HCA I)variant V62N/H67N/H200T	Homo sapiens	carbon dioxide	2.2 × 10⁵	7.5	2.9 × 10⁴	pH 7.23, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant V62N/H67N/H200T, carbon dioxide
carbonic anhydrase I (HCA I)variant V62N/H67N/H200T	Homo sapiens	carbon dioxide	5.1 × 10³	3.6	1.4 × 10³	pH 6.28, 25 °C	PMID 7758465	Open record: carbonic anhydrase I (HCA I) variant V62N/H67N/H200T, carbon dioxide
carbonic anhydrase II (bCAII)	Bos taurus	4-(4-acetoxyphenylazo)benzenesulfonic acidLineweaver-Burk (L-B)	15.1	9.1	1.674	pH 8.5, 20 °C	PMID 42255016	Open record: carbonic anhydrase II (bCAII), 4-(4-acetoxyphenylazo)benzenesulfonic acid
carbonic anhydrase II (bCAII)	Bos taurus	4-(4-acetoxyphenylazo)benzenesulfonic acidEisenthal-Cornish-Bowden (E-C-B)	16.2	9.5	1.697	pH 8.5, 20 °C	PMID 42255016	Open record: carbonic anhydrase II (bCAII), 4-(4-acetoxyphenylazo)benzenesulfonic acid
carbonic anhydrase II (bCAII)	Bos taurus	4-(4-acetoxyphenylazo)benzenesulfonic acidArrhenius	—	—	2.251	pH 8.5	PMID 42255016	Open record: carbonic anhydrase II (bCAII), 4-(4-acetoxyphenylazo)benzenesulfonic acid
carbonic anhydrase II (bCAII)	Bos taurus	4-(4-acetoxyphenylazo)benzenesulfonic acidtransition state theory (TST)	—	—	2.249	pH 8.5	PMID 42255016	Open record: carbonic anhydrase II (bCAII), 4-(4-acetoxyphenylazo)benzenesulfonic acid
carbonic anhydrase II (bCAII)	Bos taurus	p-nitrophenyl acetateArrhenius	—	—	0.409	pH 8.5	PMID 42255016	Open record: carbonic anhydrase II (bCAII), p-nitrophenyl acetate
carbonic anhydrase II (bCAII)	Bos taurus	p-nitrophenyl acetatetransition state theory (TST)	—	—	0.413	pH 8.5	PMID 42255016	Open record: carbonic anhydrase II (bCAII), p-nitrophenyl acetate
carbonic anhydrase IX	Homo sapiens	carbon dioxideno added metal; CA domain only; GST tag removed	3.8 × 10⁵	6.9	5.5 × 10⁴	pH 7.5	PMID 18703501	Open record: carbonic anhydrase IX, carbon dioxide
carbonic anhydrase IX	Homo sapiens	carbon dioxideno added metal; CA domain only	3.8 × 10⁵	7	5.4 × 10⁴	pH 7.5	PMID 18703501	Open record: carbonic anhydrase IX, carbon dioxide
carbonic anhydrase IX	Homo sapiens	carbon dioxidewith 50 µM ZnCl2; CA domain only	4.2 × 10⁶	7.5	5.6 × 10⁵	pH 7.5	PMID 18703501	Open record: carbonic anhydrase IX, carbon dioxide
carbonic anhydrase IX	Homo sapiens	carbon dioxideno added metal; PG + CA domains (extracellular domain)	1.1 × 10⁶	7.5	1.5 × 10⁵	pH 7.5	PMID 18703501	Open record: carbonic anhydrase IX, carbon dioxide
carbonic anhydrase IX	Homo sapiens	carbon dioxidewith 50 µM ZnCl2; PG + CA domains (extracellular domain)	2.5 × 10⁷	7.3	3.4 × 10⁶	pH 7.5	PMID 18703501	Open record: carbonic anhydrase IX, carbon dioxide
carbonic anhydrase IX	Homo sapiens	carbon dioxidewith 50 µM MgCl2; PG + CA domains (extracellular domain)	1.1 × 10⁷	7.3	1.5 × 10⁶	pH 7.5	PMID 18703501	Open record: carbonic anhydrase IX, carbon dioxide
carbonic anhydrase IX	Homo sapiens	carbon dioxidewith 50 µM CoCl2; PG + CA domains (extracellular domain)	1.2 × 10⁷	7.3	1.5 × 10⁶	pH 7.5	PMID 18703501	Open record: carbonic anhydrase IX, carbon dioxide
carbonic anhydrase IX	Homo sapiens	carbon dioxidewith 50 µM MnSO4; PG + CA domains (extracellular domain)	2.5 × 10⁷	7.3	3.4 × 10⁶	pH 7.5	PMID 18703501	Open record: carbonic anhydrase IX, carbon dioxide
α-carbonic anhydrase SazCA	Sulfurihydrogenibium azorense	carbon dioxideL-Phe	1.5 × 10⁷	—	—	pH 7.5, 25 °C	PMID 23294703	Open record: α-carbonic anhydrase SazCA, carbon dioxide
α-carbonic anhydrase SazCA	Sulfurihydrogenibium azorense	carbon dioxideD-Phe	3.3 × 10⁷	—	—	pH 7.5, 25 °C	PMID 23294703	Open record: α-carbonic anhydrase SazCA, carbon dioxide