Values CatLog read from this paper
Structure-guided design of a methyl donor cofactor that controls a viral histone H3 lysine 27 methyltransferase activity
PMID 21958314doi:10.1021/jm201000jOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 11 records (33 values) from this paper: vSET from Paramecium bursaria chlorella virus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| vSET | Paramecium bursaria chlorella virus | (±)-2′,3′-dibenzyl-S-adenosyl-L-methionine | 0.0062 | 0.173 | 0.03565 | pH 8 | Open record: vSET, (±)-2′,3′-dibenzyl-S-adenosyl-L-methionine |
| vSET | Paramecium bursaria chlorella virus | (±)-2′-benzyl-S-adenosyl-L-methionine | 0.0022 | 0.086 | 0.0252 | pH 8 | Open record: vSET, (±)-2′-benzyl-S-adenosyl-L-methionine |
| vSET | Paramecium bursaria chlorella virus | (±)-3′-benzyl-S-adenosyl-L-methionine | 0.0023 | 0.086 | 0.02713 | pH 8 | Open record: vSET, (±)-3′-benzyl-S-adenosyl-L-methionine |
| vSET | Paramecium bursaria chlorella virus | S-adenosyl-L-methionine | 0.065 | 0.126 | 0.5159 | pH 8 | Open record: vSET, S-adenosyl-L-methionine |
| vSETvariant L116A | Paramecium bursaria chlorella virus | (±)-2′,3′-dibenzyl-S-adenosyl-L-methionine | 0.022 | 0.072 | 0.3009 | pH 8 | Open record: vSET variant L116A, (±)-2′,3′-dibenzyl-S-adenosyl-L-methionine |
| vSETvariant L116A | Paramecium bursaria chlorella virus | (±)-2′-benzyl-S-adenosyl-L-methionine | 0.002 | 0.128 | 0.01563 | pH 8 | Open record: vSET variant L116A, (±)-2′-benzyl-S-adenosyl-L-methionine |
| vSETvariant L116A | Paramecium bursaria chlorella virus | (±)-3′-benzyl-S-adenosyl-L-methionine | 0.0025 | 0.137 | 0.01825 | pH 8 | Open record: vSET variant L116A, (±)-3′-benzyl-S-adenosyl-L-methionine |
| vSETvariant L116A | Paramecium bursaria chlorella virus | S-adenosyl-L-methionine | 0.123 | 0.06 | 2.056 | pH 8 | Open record: vSET variant L116A, S-adenosyl-L-methionine |
| vSETvariant Y109G | Paramecium bursaria chlorella virus | (±)-2′,3′-dibenzyl-S-adenosyl-L-methionine | 4 × 10⁻⁵ | 0.917 | 4.3 × 10⁻⁵ | pH 8 | Open record: vSET variant Y109G, (±)-2′,3′-dibenzyl-S-adenosyl-L-methionine |
| vSETvariant Y109G | Paramecium bursaria chlorella virus | (±)-3′-benzyl-S-adenosyl-L-methionine | 8.2 × 10⁻⁶ | 2.8 | 3 × 10⁻⁶ | pH 8 | Open record: vSET variant Y109G, (±)-3′-benzyl-S-adenosyl-L-methionine |
| vSETvariant Y109G | Paramecium bursaria chlorella virus | S-adenosyl-L-methionine | 8 × 10⁻⁶ | 0.062 | 1.28 × 10⁻⁴ | pH 8 | Open record: vSET variant Y109G, S-adenosyl-L-methionine |