Values CatLog read from this paper
Flavin-Containing Monooxygenase 3 Polymorphic Variants Significantly Affect Clearance of Tamoxifen and Clomiphene
PMID 29959872doi:10.1111/bcpt.13089Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (36 values) from this paper: flavin-containing monooxygenase 3 (hFMO3) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 1.14.13.8, EC 1.14.13.32, EC 1.14.13.148
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| flavin-containing monooxygenase 3 (hFMO3) | Homo sapiens | Clomiphene | 0.0012 | 0.0183 | 0.067 | pH 7.4, 37 °C | Open record: flavin-containing monooxygenase 3 (hFMO3), Clomiphene |
| flavin-containing monooxygenase 3 (hFMO3) | Homo sapiens | GSK5182 | 0.037 | 0.00982 | 3.7 | pH 7.4, 37 °C | Open record: flavin-containing monooxygenase 3 (hFMO3), GSK5182 |
| flavin-containing monooxygenase 3 (hFMO3) | Homo sapiens | Tamoxifen | 0.0188 | 0.0064 | 3 | pH 7.4, 37 °C | Open record: flavin-containing monooxygenase 3 (hFMO3), Tamoxifen |
| flavin-containing monooxygenase 3 (hFMO3)variant E158K | Homo sapiens | Clomiphene | 0.001 | 0.02046 | 0.05 | pH 7.4, 37 °C | Open record: flavin-containing monooxygenase 3 (hFMO3) variant E158K, Clomiphene |
| flavin-containing monooxygenase 3 (hFMO3)variant E158K | Homo sapiens | GSK5182 | 0.0193 | 0.00457 | 4.2 | pH 7.4, 37 °C | Open record: flavin-containing monooxygenase 3 (hFMO3) variant E158K, GSK5182 |
| flavin-containing monooxygenase 3 (hFMO3)variant E158K | Homo sapiens | Tamoxifen | 0.0075 | 0.00156 | 4.8 | pH 7.4, 37 °C | Open record: flavin-containing monooxygenase 3 (hFMO3) variant E158K, Tamoxifen |
| flavin-containing monooxygenase 3 (hFMO3)variant E308G | Homo sapiens | Clomiphene | 0.0042 | 0.0444 | 0.1 | pH 7.4, 37 °C | Open record: flavin-containing monooxygenase 3 (hFMO3) variant E308G, Clomiphene |
| flavin-containing monooxygenase 3 (hFMO3)variant E308G | Homo sapiens | GSK5182 | 0.02 | 0.00587 | 3.3 | pH 7.4, 37 °C | Open record: flavin-containing monooxygenase 3 (hFMO3) variant E308G, GSK5182 |
| flavin-containing monooxygenase 3 (hFMO3)variant E308G | Homo sapiens | Tamoxifen | 0.0063 | 0.0025 | 2.5 | pH 7.4, 37 °C | Open record: flavin-containing monooxygenase 3 (hFMO3) variant E308G, Tamoxifen |
| flavin-containing monooxygenase 3 (hFMO3)variant V257M | Homo sapiens | Clomiphene | 0.005 | 0.0332 | 0.15 | pH 7.4, 37 °C | Open record: flavin-containing monooxygenase 3 (hFMO3) variant V257M, Clomiphene |
| flavin-containing monooxygenase 3 (hFMO3)variant V257M | Homo sapiens | GSK5182 | 0.0948 | 0.0285 | 3.2 | pH 7.4, 37 °C | Open record: flavin-containing monooxygenase 3 (hFMO3) variant V257M, GSK5182 |
| flavin-containing monooxygenase 3 (hFMO3)variant V257M | Homo sapiens | Tamoxifen | 0.01 | 0.0081 | 1.2 | pH 7.4, 37 °C | Open record: flavin-containing monooxygenase 3 (hFMO3) variant V257M, Tamoxifen |