Values CatLog read from this paper
Phage-assisted continuous evolution of enzymes for noncanonical tyrosine biosynthesis
PMID 42721086doi:10.1073/pnas.2614167123Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (36 values) from this paper: tyrosine phenol lyase (CfTPL), tyrosine synthase (TyrS) from Citrobacter freundii.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| tyrosine phenol lyase (CfTPL)variant M379V | Citrobacter freundii | 3-iodotyrosine | 0.042 | 0.267 | 0.156 | pH 8, 37 °C | Open record: tyrosine phenol lyase (CfTPL) variant M379V, 3-iodotyrosine |
| tyrosine phenol lyase (CfTPL)variant M379V | Citrobacter freundii | L-tyrosine | 0.25 | 0.814 | 0.307 | pH 8, 37 °C | Open record: tyrosine phenol lyase (CfTPL) variant M379V, L-tyrosine |
| tyrosine phenol lyase (CfTPL)variant M379V/C179S (N1.2-4) | Citrobacter freundii | 3-iodotyrosine | 0.042 | 0.248 | 0.169 | pH 8, 37 °C | Open record: tyrosine phenol lyase (CfTPL) variant M379V/C179S (N1.2-4), 3-iodotyrosine |
| tyrosine phenol lyase (CfTPL)variant M379V/C179S (N1.2-4) | Citrobacter freundii | L-tyrosine | 0.283 | 0.767 | 0.37 | pH 8, 37 °C | Open record: tyrosine phenol lyase (CfTPL) variant M379V/C179S (N1.2-4), L-tyrosine |
| tyrosine phenol lyase (CfTPL)variant M379V/V16I/V141I/C179S/N390H (N2.2-1) | Citrobacter freundii | 3-iodotyrosine | 0.057 | 0.392 | 0.146 | pH 8, 37 °C | Open record: tyrosine phenol lyase (CfTPL) variant M379V/V16I/V141I/C179S/N390H (N2.2-1), 3-iodotyrosine |
| tyrosine phenol lyase (CfTPL)variant M379V/V16I/V141I/C179S/N390H (N2.2-1) | Citrobacter freundii | L-tyrosine | 0.19 | 1.048 | 0.182 | pH 8, 37 °C | Open record: tyrosine phenol lyase (CfTPL) variant M379V/V16I/V141I/C179S/N390H (N2.2-1), L-tyrosine |
| tyrosine synthase (TyrS)variant N6-1 | — | 2-bromophenol | 0.023 | 0.145 | 0.16 | pH 8, 37 °C | Open record: tyrosine synthase (TyrS) variant N6-1, 2-bromophenol |
| tyrosine synthase (TyrS)variant N8-1 | — | 2-bromophenol | 0.022 | 0.145 | 0.156 | pH 8, 37 °C | Open record: tyrosine synthase (TyrS) variant N8-1, 2-bromophenol |
| tyrosine synthase (TyrS)variant P1-1 | — | 2-bromophenol | 0.02 | 0.178 | 0.117 | pH 8, 37 °C | Open record: tyrosine synthase (TyrS) variant P1-1, 2-bromophenol |
| tyrosine synthase (TyrS)variant P2-1 | — | 2-bromophenol | 0.027 | 0.187 | 0.142 | pH 8, 37 °C | Open record: tyrosine synthase (TyrS) variant P2-1, 2-bromophenol |
| tyrosine synthase (TyrS)variant P3-3 | — | 2-bromophenol | 0.0067 | 0.044 | 0.15 | pH 8, 37 °C | Open record: tyrosine synthase (TyrS) variant P3-3, 2-bromophenol |
| tyrosine synthase (TyrS)variant TyrS4 | — | 2-bromophenol | 0.02 | 0.336 | 0.062 | pH 8, 37 °C | Open record: tyrosine synthase (TyrS) variant TyrS4, 2-bromophenol |