Values CatLog read from this paper

Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis

PMID 16787777doi:10.1016/j.jmb.2006.04.051Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 12 records (36 values) from this paper: caspase-3 from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.22.56

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
caspase-3	Homo sapiens	N-acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Ac-Asp-Glu-Val-Asp-AMC)	6.01	0.0138	440	pH 7.2, 37 °C	Open record: caspase-3, N-acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Ac-Asp-Glu-Val-Asp-AMC)
caspase-3	Homo sapiens	N-acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Ac-Asp-Glu-Val-Asp-AMC)	0.33	0.0122	27	pH 4.75, 37 °C	Open record: caspase-3, N-acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Ac-Asp-Glu-Val-Asp-AMC)
caspase-3	Homo sapiens	N-benzyloxycarbonyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Z-Asp-Glu-Val-Asp-AMC)	7.08	0.0097	720	pH 7.2, 37 °C	Open record: caspase-3, N-benzyloxycarbonyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Z-Asp-Glu-Val-Asp-AMC)
caspase-3	Homo sapiens	N-benzyloxycarbonyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Z-Asp-Glu-Val-Asp-AMC)	0.16	0.008	20	pH 4.75, 37 °C	Open record: caspase-3, N-benzyloxycarbonyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Z-Asp-Glu-Val-Asp-AMC)
caspase-3variant D179A	Homo sapiens	N-acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Ac-Asp-Glu-Val-Asp-AMC)	19.56	0.0335	580	pH 7.2, 37 °C	Open record: caspase-3 variant D179A, N-acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Ac-Asp-Glu-Val-Asp-AMC)
caspase-3variant D179A	Homo sapiens	N-acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Ac-Asp-Glu-Val-Asp-AMC)	1.37	0.0163	83	pH 4.75, 37 °C	Open record: caspase-3 variant D179A, N-acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Ac-Asp-Glu-Val-Asp-AMC)
caspase-3variant D179A	Homo sapiens	N-benzyloxycarbonyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Z-Asp-Glu-Val-Asp-AMC)	19.04	0.0255	740	pH 7.2, 37 °C	Open record: caspase-3 variant D179A, N-benzyloxycarbonyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Z-Asp-Glu-Val-Asp-AMC)
caspase-3variant D179A	Homo sapiens	N-benzyloxycarbonyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Z-Asp-Glu-Val-Asp-AMC)	1.1	0.013	84	pH 4.75, 37 °C	Open record: caspase-3 variant D179A, N-benzyloxycarbonyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Z-Asp-Glu-Val-Asp-AMC)
caspase-3variant Δ176-181	Homo sapiens	N-acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Ac-Asp-Glu-Val-Asp-AMC)	1.54	0.0088	180	pH 7.2, 37 °C	Open record: caspase-3 variant Δ176-181, N-acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Ac-Asp-Glu-Val-Asp-AMC)
caspase-3variant Δ176-181	Homo sapiens	N-acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Ac-Asp-Glu-Val-Asp-AMC)	0.08	0.0048	16	pH 4.75, 37 °C	Open record: caspase-3 variant Δ176-181, N-acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Ac-Asp-Glu-Val-Asp-AMC)
caspase-3variant Δ176-181	Homo sapiens	N-benzyloxycarbonyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Z-Asp-Glu-Val-Asp-AMC)	1.43	0.0069	210	pH 7.2, 37 °C	Open record: caspase-3 variant Δ176-181, N-benzyloxycarbonyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Z-Asp-Glu-Val-Asp-AMC)
caspase-3variant Δ176-181	Homo sapiens	N-benzyloxycarbonyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Z-Asp-Glu-Val-Asp-AMC)	0.06	0.002	33	pH 4.75, 37 °C	Open record: caspase-3 variant Δ176-181, N-benzyloxycarbonyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid 7-amido-4-methylcoumarin (Z-Asp-Glu-Val-Asp-AMC)