Values CatLog read from this paper
Engineered inhibitor sensitivity in the WPD loop of a protein tyrosine phosphatase
PMID 18358001doi:10.1021/bi800014cOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 48 records (144 values) from this paper: T-cell protein tyrosine phosphatase (TCPTP) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| T-cell protein tyrosine phosphatase (TCPTP) | Homo sapiens | DADEpYLIPQQGDMSO vehicle only (no FlAsH) | 26 | 0.0098 | 2.7 × 10³ | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP), DADEpYLIPQQG |
| T-cell protein tyrosine phosphatase (TCPTP) | Homo sapiens | DADEpYLIPQQG10 µM FlAsH | 23 | 0.0089 | 2.6 × 10³ | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP), DADEpYLIPQQG |
| T-cell protein tyrosine phosphatase (TCPTP) | Homo sapiens | p-nitrophenyl phosphatepNPP 0.25-10 mM; Michaelis-Menten fit; Table 1 | 5.1 | 2.5 | 2.1 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP), p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP) | Homo sapiens | p-nitrophenyl phosphateTable 2 | 4.4 | 2.3 | 1.9 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP), p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP) | Homo sapiens | p-nitrophenyl phosphateTable 2 | 4.1 | 2.3 | 1.8 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP), p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 2C-1 | Homo sapiens | p-nitrophenyl phosphate | 9.5 | 1.4 | 6.7 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 2C-1, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 2C-2 | Homo sapiens | p-nitrophenyl phosphate | 0.3 | 3.7 | 0.082 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 2C-2, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 2C-3 | Homo sapiens | p-nitrophenyl phosphate | 12 | 1.2 | 10 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 2C-3, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-1 | Homo sapiens | DADEpYLIPQQGDMSO vehicle only (no FlAsH) | 13 | 0.011 | 1.2 × 10³ | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-1, DADEpYLIPQQG |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-1 | Homo sapiens | DADEpYLIPQQG10 µM FlAsH | 1.2 | 0.025 | 48 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-1, DADEpYLIPQQG |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-1 | Homo sapiens | p-nitrophenyl phosphatepNPP 0.25-10 mM; Michaelis-Menten fit; Table 1 | 3.3 | 2.1 | 1.6 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-1, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-1 | Homo sapiens | p-nitrophenyl phosphateTable 2 | 2.9 | 2.1 | 1.4 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-1, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-1 | Homo sapiens | p-nitrophenyl phosphateTable 2 | 0.41 | 2.8 | 0.15 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-1, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-2 | Homo sapiens | DADEpYLIPQQGDMSO vehicle only (no FlAsH) | 6.3 | 0.0085 | 750 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-2, DADEpYLIPQQG |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-2 | Homo sapiens | DADEpYLIPQQG10 µM FlAsH | 0.75 | 0.017 | 46 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-2, DADEpYLIPQQG |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-2 | Homo sapiens | p-nitrophenyl phosphatepNPP 0.25-10 mM; Michaelis-Menten fit; Table 1 | 2.6 | 1.4 | 1.8 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-2, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-2 | Homo sapiens | p-nitrophenyl phosphateTable 2 | 1.9 | 1.4 | 1.4 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-2, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-2 | Homo sapiens | p-nitrophenyl phosphateTable 2 | 0.18 | 2.2 | 0.081 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-2, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-3 | Homo sapiens | p-nitrophenyl phosphate | 0.13 | 2.7 | 0.047 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-3, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-4 | Homo sapiens | p-nitrophenyl phosphate | 0.72 | 3.5 | 0.21 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-4, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-5 | Homo sapiens | p-nitrophenyl phosphate | 1.6 | 1.4 | 1.2 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-5, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 3C-6 | Homo sapiens | p-nitrophenyl phosphate | 2.4 | 1.1 | 2.2 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 3C-6, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 4C-1 | Homo sapiens | p-nitrophenyl phosphate | 1 | 2.3 | 0.44 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 4C-1, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 4C-2 | Homo sapiens | p-nitrophenyl phosphate | 0.89 | 1.7 | 0.51 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 4C-2, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 4C-3 | Homo sapiens | DADEpYLIPQQGDMSO vehicle only (no FlAsH) | 26 | 0.014 | 1.9 × 10³ | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 4C-3, DADEpYLIPQQG |
| T-cell protein tyrosine phosphatase (TCPTP)variant 4C-3 | Homo sapiens | DADEpYLIPQQG10 µM FlAsH | 2.7 | 0.015 | 180 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 4C-3, DADEpYLIPQQG |
| T-cell protein tyrosine phosphatase (TCPTP)variant 4C-3 | Homo sapiens | p-nitrophenyl phosphatepNPP 0.25-10 mM; Michaelis-Menten fit; Table 1 | 8.7 | 1.6 | 5.4 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 4C-3, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 4C-3 | Homo sapiens | p-nitrophenyl phosphateTable 2 | 8.9 | 1.5 | 5.8 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 4C-3, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 4C-3 | Homo sapiens | p-nitrophenyl phosphateTable 2 | 1.3 | 1.6 | 0.82 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 4C-3, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant 4C-4 | Homo sapiens | p-nitrophenyl phosphate | 0.079 | 3.8 | 0.021 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant 4C-4, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant E187C | Homo sapiens | p-nitrophenyl phosphate | 3.5 | 2.7 | 1.3 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant E187C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant E187C/S188C | Homo sapiens | p-nitrophenyl phosphate | 5.4 | 2.3 | 2.4 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant E187C/S188C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant F183C | Homo sapiens | p-nitrophenyl phosphate | 0.83 | 3.1 | 0.26 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant F183C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant G184C | Homo sapiens | p-nitrophenyl phosphate | 4.4 | 1.3 | 3.4 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant G184C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant P181C | Homo sapiens | p-nitrophenyl phosphate | 9.8 | 0.54 | 18 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P181C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant P181C/E187C | Homo sapiens | DADEpYLIPQQGDMSO vehicle only (no FlAsH) | 15 | 0.01 | 1.5 × 10³ | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P181C/E187C, DADEpYLIPQQG |
| T-cell protein tyrosine phosphatase (TCPTP)variant P181C/E187C | Homo sapiens | DADEpYLIPQQG10 µM FlAsH | 1.8 | 0.017 | 110 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P181C/E187C, DADEpYLIPQQG |
| T-cell protein tyrosine phosphatase (TCPTP)variant P181C/E187C | Homo sapiens | p-nitrophenyl phosphatepNPP 0.25-10 mM; Michaelis-Menten fit; Table 1 | 6.4 | 0.85 | 7.6 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P181C/E187C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant P181C/E187C | Homo sapiens | p-nitrophenyl phosphateTable 2 | 5.7 | 0.82 | 7 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P181C/E187C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant P181C/E187C | Homo sapiens | p-nitrophenyl phosphateTable 2 | 0.72 | 1.2 | 0.59 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P181C/E187C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant P181C/P186C | Homo sapiens | DADEpYLIPQQGDMSO vehicle only (no FlAsH) | 14 | 0.0081 | 1.8 × 10³ | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P181C/P186C, DADEpYLIPQQG |
| T-cell protein tyrosine phosphatase (TCPTP)variant P181C/P186C | Homo sapiens | DADEpYLIPQQG10 µM FlAsH | 1.9 | 0.013 | 140 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P181C/P186C, DADEpYLIPQQG |
| T-cell protein tyrosine phosphatase (TCPTP)variant P181C/P186C | Homo sapiens | p-nitrophenyl phosphatepNPP 0.25-10 mM; Michaelis-Menten fit; Table 1 | 3.2 | 1.9 | 1.7 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P181C/P186C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant P181C/P186C | Homo sapiens | p-nitrophenyl phosphateTable 2 | 2.8 | 2 | 1.4 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P181C/P186C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant P181C/P186C | Homo sapiens | p-nitrophenyl phosphateTable 2 | 0.31 | 2.6 | 0.12 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P181C/P186C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant P186C | Homo sapiens | p-nitrophenyl phosphate | 3.7 | 2.5 | 1.5 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P186C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant P186C/E187C | Homo sapiens | p-nitrophenyl phosphate | 1.7 | 3.1 | 0.53 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant P186C/E187C, p-nitrophenyl phosphate |
| T-cell protein tyrosine phosphatase (TCPTP)variant V185C | Homo sapiens | p-nitrophenyl phosphate | 3.9 | 2.7 | 1.5 | pH 7, 22 °C | Open record: T-cell protein tyrosine phosphatase (TCPTP) variant V185C, p-nitrophenyl phosphate |