Values CatLog read from this paper
Non-active site mutation (Q123A) in New Delhi metallo-β-lactamase (NDM-1) enhanced its enzyme activity
PMID 29454953doi:10.1016/j.ijbiomac.2018.02.091Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 14 records (42 values) from this paper: NDM-1 (New Delhi metallo-beta-lactamase-1) from Klebsiella pneumoniae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| NDM-1 (New Delhi metallo-beta-lactamase-1) | Klebsiella pneumoniae | ampicillin | 469.6 | 0.148 | 3172 | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1), ampicillin |
| NDM-1 (New Delhi metallo-beta-lactamase-1) | Klebsiella pneumoniae | cefotaxime | 84.84 | 0.03194 | 2631 | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1), cefotaxime |
| NDM-1 (New Delhi metallo-beta-lactamase-1) | Klebsiella pneumoniae | cefoxitin | 348 | 0.05071 | 6962 | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1), cefoxitin |
| NDM-1 (New Delhi metallo-beta-lactamase-1) | Klebsiella pneumoniae | ceftazidime | 119.2 | 0.03843 | 3102 | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1), ceftazidime |
| NDM-1 (New Delhi metallo-beta-lactamase-1) | Klebsiella pneumoniae | imipenem | 323.3 | 0.03174 | 1.061 × 10⁴ | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1), imipenem |
| NDM-1 (New Delhi metallo-beta-lactamase-1) | Klebsiella pneumoniae | meropenem | 263.9 | 0.04442 | 7733 | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1), meropenem |
| NDM-1 (New Delhi metallo-beta-lactamase-1) | Klebsiella pneumoniae | nitrocefin | 1.332 | 0.01272 | 104 | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1), nitrocefin |
| NDM-1 (New Delhi metallo-beta-lactamase-1)variant Q123A | Klebsiella pneumoniae | ampicillin | 680.5 | 0.03255 | 2.09 × 10⁴ | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1) variant Q123A, ampicillin |
| NDM-1 (New Delhi metallo-beta-lactamase-1)variant Q123A | Klebsiella pneumoniae | cefotaxime | 127.2 | 0.02551 | 4986 | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1) variant Q123A, cefotaxime |
| NDM-1 (New Delhi metallo-beta-lactamase-1)variant Q123A | Klebsiella pneumoniae | cefoxitin | 366.8 | 0.02864 | 12,807 | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1) variant Q123A, cefoxitin |
| NDM-1 (New Delhi metallo-beta-lactamase-1)variant Q123A | Klebsiella pneumoniae | ceftazidime | 254.3 | 0.02957 | 8599 | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1) variant Q123A, ceftazidime |
| NDM-1 (New Delhi metallo-beta-lactamase-1)variant Q123A | Klebsiella pneumoniae | imipenem | 678.2 | 0.02488 | 2.725 × 10⁴ | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1) variant Q123A, imipenem |
| NDM-1 (New Delhi metallo-beta-lactamase-1)variant Q123A | Klebsiella pneumoniae | meropenem | 486.5 | 0.02579 | 1.886 × 10⁴ | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1) variant Q123A, meropenem |
| NDM-1 (New Delhi metallo-beta-lactamase-1)variant Q123A | Klebsiella pneumoniae | nitrocefin | 96 | 0.009507 | 1.009 × 10⁴ | pH 7, 30 °C | Open record: NDM-1 (New Delhi metallo-beta-lactamase-1) variant Q123A, nitrocefin |