Values CatLog read from this paper

Design, synthesis, and biological evaluation of novel human 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP) substrates

PMID 15911263doi:10.1016/j.bmcl.2005.03.107Open in Browse

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CatLog read 34 records (100 values) from this paper: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.4.2.28

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	5'-deoxy-5'-methylthioadenosine	4.6	0.0018	3.2 × 10³	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), 5'-deoxy-5'-methylthioadenosine
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 10	2.3	0.0031	740	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 10
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 11	5.9	0.004	1.48 × 10³	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 11
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 12	1.46	0.025	58	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 12
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 13	0.85	0.017	50	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 13
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 14	5.5	0.0028	1.96 × 10³	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 14
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 15	4.2	0.005	840	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 15
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 16	0.23	8.8 × 10⁻⁴	260	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 16
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 17	3.44	0.0052	660	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 17
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 18	3.16	0.0069	460	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 18
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 19	1.5	0.003	500	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 19
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 2 (R5' = H, R3' = OH, R2' = OH)	4.8	0.006	800	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 2 (R5' = H, R3' = OH, R2' = OH)
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 20	3.8	0.009	420	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 20
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 21	2.49	0.0034	730	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 21
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 22	2.5	0.0046	530	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 22
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 23	2.14	0.005	430	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 23
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 24	1.01	0.0102	90	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 24
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 25	1.57	0.0035	450	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 25
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 26	1.5	0.0032	470	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 26
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 27	0.8	0.007	110	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 27
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 28	0.3	0.0017	170	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 28
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 29	1.4	0.0015	930	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 29
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 3 (R5' = CH3S, R3' = OH, R2' = H)	0.28	0.0031	90	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 3 (R5' = CH3S, R3' = OH, R2' = H)
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 30	2.4	0.002	1.2 × 10³	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 30
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 31	0.18	0.0056	30	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 31
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 32	1.11	0.012	90	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 32
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 33	2.02	0.0085	240	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 33
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 34	4.6	0.0013	3.5 × 10³	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 34
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 4 (R5' = CH3S, R3' = H, R2' = OH)	0.004	0.0039	1	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 4 (R5' = CH3S, R3' = H, R2' = OH)
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 5 (R5' = CH3S, R3' = OH, R2' = F)	4 × 10⁻⁴	—	—	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 5 (R5' = CH3S, R3' = OH, R2' = F)
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 6 (R5' = CH3S, R3' = OH, R2' = N3)	0.04	3.6	0.011	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 6 (R5' = CH3S, R3' = OH, R2' = N3)
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 7 (R5' = CH3S, R3' = OH, R2' = OH, stereochemistry R)	0.0065	0.106	0.1	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 7 (R5' = CH3S, R3' = OH, R2' = OH, stereochemistry R)
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 8 (R5' = CH3S, R3' = OH, R2' = NH2)	0.67	0.03	22	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 8 (R5' = CH3S, R3' = OH, R2' = NH2)
5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP)	Homo sapiens	compound 9 (ETA)	2.9	0.0018	1.6 × 10³	37 °C	Open record: 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP), compound 9 (ETA)