Values CatLog read from this paper
Human mitochondrial MTHFD2 is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
PMID 29225823doi:10.1186/s40170-017-0173-0Open in Browse
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CatLog read 4 records (12 values) from this paper: MTHFD2 (mitochondrial bifunctional 5,10-methylene-THF dehydrogenase/5,10-methenyl-THF cyclohydrolase) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| MTHFD2 (mitochondrial bifunctional 5,10-methylene-THF dehydrogenase/5,10-methenyl-THF cyclohydrolase) | Homo sapiens | 5,10-methylene-tetrahydropteroyl monoglutamate25 mM potassium phosphate; NAD+ 1.0 mM (saturating) | 12.4 | 0.133 | 93 | pH 8, 30 °C | Open record: MTHFD2 (mitochondrial bifunctional 5,10-methylene-THF dehydrogenase/5,10-methenyl-THF cyclohydrolase), 5,10-methylene-tetrahydropteroyl monoglutamate |
| MTHFD2 (mitochondrial bifunctional 5,10-methylene-THF dehydrogenase/5,10-methenyl-THF cyclohydrolase) | Homo sapiens | 5,10-methylene-tetrahydropteroyl monoglutamateno phosphate; NADP+ 6.0 mM (saturating); cosubstrate NADP+ | 1.5 | 0.123 | 12 | pH 8, 30 °C | Open record: MTHFD2 (mitochondrial bifunctional 5,10-methylene-THF dehydrogenase/5,10-methenyl-THF cyclohydrolase), 5,10-methylene-tetrahydropteroyl monoglutamate |
| MTHFD2 (mitochondrial bifunctional 5,10-methylene-THF dehydrogenase/5,10-methenyl-THF cyclohydrolase) | Homo sapiens | 5,10-methylene-tetrahydropteroyl pentaglutamate25 mM potassium phosphate; NAD+ 1.0 mM (saturating) | 15.4 | 0.359 | 43 | pH 8, 30 °C | Open record: MTHFD2 (mitochondrial bifunctional 5,10-methylene-THF dehydrogenase/5,10-methenyl-THF cyclohydrolase), 5,10-methylene-tetrahydropteroyl pentaglutamate |
| MTHFD2 (mitochondrial bifunctional 5,10-methylene-THF dehydrogenase/5,10-methenyl-THF cyclohydrolase) | Homo sapiens | 5,10-methylene-tetrahydropteroyl pentaglutamateno phosphate; NADP+ 6.0 mM (saturating); cosubstrate NADP+ | 6.4 | 0.302 | 21 | pH 8, 30 °C | Open record: MTHFD2 (mitochondrial bifunctional 5,10-methylene-THF dehydrogenase/5,10-methenyl-THF cyclohydrolase), 5,10-methylene-tetrahydropteroyl pentaglutamate |