Values CatLog read from this paper
Prodigious substrate specificity of AAC(6')-APH(2"), an aminoglycoside antibiotic resistance determinant in enterococci and staphylococci
PMID 10021417doi:10.1016/s1074-5521(99)80006-4Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 35 records (97 values) from this paper: AAC(6')-APH(2″) from Enterococcus faecalis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 4 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| AAC(6')-APH(2″) | Enterococcus faecalis | acetyl coenzyme A | 0.73 | 0.0059 | 124 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), acetyl coenzyme A |
| AAC(6')-APH(2″) | Enterococcus faecalis | amikacin | — | 0.0209 | 101 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), amikacin |
| AAC(6')-APH(2″) | Enterococcus faecalis | amikacin | 0.16 | 0.158 | 1 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), amikacin |
| AAC(6')-APH(2″) | Enterococcus faecalis | ATP | 0.17 | 0.0241 | 7.1 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), ATP |
| AAC(6')-APH(2″) | Enterococcus faecalis | butirosin A | 1.27 | 0.0258 | 49.2 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), butirosin A |
| AAC(6')-APH(2″) | Enterococcus faecalis | butirosin A | 0.43 | — | 37.1 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), butirosin A |
| AAC(6')-APH(2″) | Enterococcus faecalis | dibekacin | 1.5 | 0.0024 | 620 calc. | pH 7, 37 °C | Open record: AAC(6')-APH(2″), dibekacin |
| AAC(6')-APH(2″) | Enterococcus faecalis | dibekacin | 0.34 | 0.0036 | 94 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), dibekacin |
| AAC(6')-APH(2″) | Enterococcus faecalis | fortimicin | 0.19 | 0.0022 | 86.4 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), fortimicin |
| AAC(6')-APH(2″) | Enterococcus faecalis | gentamicin B | 0.3 | — | 273 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), gentamicin B |
| AAC(6')-APH(2″) | Enterococcus faecalis | gentamicin B | 0.65 | 0.0389 | 16.7 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), gentamicin B |
| AAC(6')-APH(2″) | Enterococcus faecalis | gentamicin C | 0.85 | 0.0046 | 185 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), gentamicin C |
| AAC(6')-APH(2″) | Enterococcus faecalis | gentamicin C | 0.23 | 0.0034 | 68 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), gentamicin C |
| AAC(6')-APH(2″) | Enterococcus faecalis | isepamicin | 1.66 | 0.0187 | 88.7 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), isepamicin |
| AAC(6')-APH(2″) | Enterococcus faecalis | isepamicin | 0.59 | 0.197 | 3 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), isepamicin |
| AAC(6')-APH(2″) | Enterococcus faecalis | kanamycin A | 0.31 | 0.0014 | 221 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), kanamycin A |
| AAC(6')-APH(2″) | Enterococcus faecalis | kanamycin A | 0.41 | 0.007 | 58.4 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), kanamycin A |
| AAC(6')-APH(2″) | Enterococcus faecalis | kanamycin B | 1.3 | 0.0075 | 170 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), kanamycin B |
| AAC(6')-APH(2″) | Enterococcus faecalis | kanamycin B | 1.07 | 0.0093 | 115 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), kanamycin B |
| AAC(6')-APH(2″) | Enterococcus faecalis | lividomycin A | 0.02 | 0.0101 | 2 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), lividomycin A |
| AAC(6')-APH(2″) | Enterococcus faecalis | lividomycin A | 0.22 | 0.0329 | 6.7 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), lividomycin A |
| AAC(6')-APH(2″) | Enterococcus faecalis | neamine | 3 | 0.0084 | 360 calc. | pH 7, 37 °C | Open record: AAC(6')-APH(2″), neamine |
| AAC(6')-APH(2″) | Enterococcus faecalis | neamine | 0.17 | 0.0096 | 18 calc. | pH 8, 36 °C | Open record: AAC(6')-APH(2″), neamine |
| AAC(6')-APH(2″) | Enterococcus faecalis | neomycin B | 1.53 | 0.0042 | 364 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), neomycin B |
| AAC(6')-APH(2″) | Enterococcus faecalis | neomycin B | 0.19 | 0.0019 | 100 calc. | pH 8, 36 °C | Open record: AAC(6')-APH(2″), neomycin B |
| AAC(6')-APH(2″) | Enterococcus faecalis | netilmicin | 0.87 | 0.0032 | 272 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), netilmicin |
| AAC(6')-APH(2″) | Enterococcus faecalis | netilmicin | 0.21 | 0.0364 | 5.77 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), netilmicin |
| AAC(6')-APH(2″) | Enterococcus faecalis | paromomycin | 0.032 | 0.0175 | 1.8 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), paromomycin |
| AAC(6')-APH(2″) | Enterococcus faecalis | paromomycin | 0.49 | 0.0034 | 144 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), paromomycin |
| AAC(6')-APH(2″) | Enterococcus faecalis | ribostamycin | 2.06 | 0.0061 | 338 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), ribostamycin |
| AAC(6')-APH(2″) | Enterococcus faecalis | ribostamycin | 0.25 | — | 371 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), ribostamycin |
| AAC(6')-APH(2″) | Enterococcus faecalis | sisomicin | 2.92 | 0.0065 | 450 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), sisomicin |
| AAC(6')-APH(2″) | Enterococcus faecalis | sisomicin | 0.4 | 0.0122 | 32.8 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), sisomicin |
| AAC(6')-APH(2″) | Enterococcus faecalis | tobramycin | 0.68 | 0.0023 | 300 | pH 7, 37 °C | Open record: AAC(6')-APH(2″), tobramycin |
| AAC(6')-APH(2″) | Enterococcus faecalis | tobramycin | 0.33 | 0.0048 | 69 | pH 8, 36 °C | Open record: AAC(6')-APH(2″), tobramycin |