Values CatLog read from this paper
Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery
PMID 25631047doi:10.1074/jbc.m114.628016Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 23 records (55 values) from this paper: nicotinate mononucleotide adenylyltransferase (MtNadD) from Mycobacterium tuberculosis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| nicotinate mononucleotide adenylyltransferase (MtNadD) | Mycobacterium tuberculosis | ATPreleased free phosphate detected colorimetrically | — | 0.041 | 134 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD), ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD) | Mycobacterium tuberculosis | ATP | — | 0.005 | — | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD), ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD) | Mycobacterium tuberculosis | nicotinic acid mononucleotidefollowed at 340 nm | 5.5 | 0.48 | 12 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD), nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD) | Mycobacterium tuberculosis | nicotinic acid mononucleotide | — | 0.48 | — | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD), nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant K47A | Mycobacterium tuberculosis | ATP | — | 0.006 | 3 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant K47A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant K47A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.02 | 2.7 | 0.007 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant K47A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant L164A | Mycobacterium tuberculosis | ATP | — | 0.17 | 0.8 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant L164A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant L164A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.13 | 0.052 | 2.5 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant L164A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant L164Q | Mycobacterium tuberculosis | ATP | — | 0.19 | 0.08 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant L164Q, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant L164Q | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.015 | 0.43 | 0.04 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant L164Q, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant P44A | Mycobacterium tuberculosis | ATP | — | 0.017 | 21 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant P44A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant P44A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.36 | 0.84 | 0.4 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant P44A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant Q46A | Mycobacterium tuberculosis | ATP | — | 0.033 | 142 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant Q46A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant Q46A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 4.7 | 0.33 | 14 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant Q46A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant T12A | Mycobacterium tuberculosis | ATP | — | 0.042 | 5 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant T12A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant T12A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.22 | 0.53 | 0.4 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant T12A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant T86A | Mycobacterium tuberculosis | ATP | — | 0.011 | 18 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant T86A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant T86A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.2 | 2.8 | 0.07 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant T86A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant W117A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.002 | 2.67 | 8 × 10⁻⁴ | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant W117A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant W117F | Mycobacterium tuberculosis | ATP | — | 0.023 | 1.3 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant W117F, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant W117F | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.03 | 1.13 | 0.03 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant W117F, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant W45A | Mycobacterium tuberculosis | ATP | — | 0.011 | 34 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant W45A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant W45A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.37 | 0.98 | 0.4 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant W45A, nicotinic acid mononucleotide |