EC 2.7.7.18: nicotinate-nucleotide adenylyltransferase
TransferasesOpen in Browse
CatLog read 58 records for EC 2.7.7.18 from 6 papers, for 6 organisms. Names in these papers: nicotinate mononucleotide adenylyltransferase (MtNadD), nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT), NadD (nicotinic acid mononucleotide adenylyltransferase), NMNAT1 and 5 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 12 records for EC 2.7.7.18 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.7.18 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery | Mycobacterium tuberculosis | 23 |
| Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms | Homo sapiens | 12 |
| Structural and Functional Characterization of Plasmodium falciparum Nicotinic Acid Mononucleotide Adenylyltransferase | Plasmodium falciparum | 12 |
| Engineering Escherichia coli Nicotinic Acid Mononucleotide Adenylyltransferase for Fully Active Amidated NAD Biosynthesis | Escherichia coli | 6 |
| The deamido-diphosphopyridine nucleotide and diphosphopyridine nucleotide pyrophosphorylases of Escherichia coli and yeast | Escherichia coli, yeast | 3 |
| Genomics-driven reconstruction of acinetobacter NAD metabolism: insights for antibacterial target selection | Acinetobacter baylyi | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| deamido-DPN (DPN) pyrophosphorylase | Escherichia coli | adenosine 5'-triphosphate | — | 0.5 | — | pH 7.5, 37 °C | PMID 4291828 | Open record: deamido-DPN (DPN) pyrophosphorylase, adenosine 5'-triphosphate |
| deamido-DPN (DPN) pyrophosphorylase | Escherichia coli | nicotinamide mononucleotide | — | 0.2 | — | pH 7.5, 37 °C | PMID 4291828 | Open record: deamido-DPN (DPN) pyrophosphorylase, nicotinamide mononucleotide |
| DPN (deamido-DPN) pyrophosphorylase | yeast | NAD+ | — | 0.069 | — | pH 7.5, 37 °C | PMID 4291828 | Open record: DPN (deamido-DPN) pyrophosphorylase, NAD+ |
| NadD (nicotinic acid mononucleotide adenylyltransferase) | Escherichia coli | nicotinamide mononucleotide | 0.76 | 9.4 | 0.08 | pH 8, 25 °C | PMID 28455340 | Open record: NadD (nicotinic acid mononucleotide adenylyltransferase), nicotinamide mononucleotide |
| NadD (nicotinic acid mononucleotide adenylyltransferase) | Escherichia coli | nicotinic acid mononucleotide | 4.9 | 0.11 | 44 | pH 8, 25 °C | PMID 28455340 | Open record: NadD (nicotinic acid mononucleotide adenylyltransferase), nicotinic acid mononucleotide |
| NadD (nicotinic acid mononucleotide adenylyltransferase)variant A86W/Y118N (16D8) | Escherichia coli | nicotinamide mononucleotide | 36 | 0.76 | 48 | pH 8, 25 °C | PMID 28455340 | Open record: NadD (nicotinic acid mononucleotide adenylyltransferase) variant A86W/Y118N (16D8), nicotinamide mononucleotide |
| NadD (nicotinic acid mononucleotide adenylyltransferase)variant A86W/Y118N (16D8) | Escherichia coli | nicotinic acid mononucleotide | 25 | 0.07 | 332 | pH 8, 25 °C | PMID 28455340 | Open record: NadD (nicotinic acid mononucleotide adenylyltransferase) variant A86W/Y118N (16D8), nicotinic acid mononucleotide |
| NadD (nicotinic acid mononucleotide adenylyltransferase)variant Y84V/Y118D (11B4) | Escherichia coli | nicotinamide mononucleotide | 6.6 | 0.8 | 8.3 | pH 8, 25 °C | PMID 28455340 | Open record: NadD (nicotinic acid mononucleotide adenylyltransferase) variant Y84V/Y118D (11B4), nicotinamide mononucleotide |
| NadD (nicotinic acid mononucleotide adenylyltransferase)variant Y84V/Y118D (11B4) | Escherichia coli | nicotinic acid mononucleotide | 1.5 | 1.7 | 0.86 | pH 8, 25 °C | PMID 28455340 | Open record: NadD (nicotinic acid mononucleotide adenylyltransferase) variant Y84V/Y118D (11B4), nicotinic acid mononucleotide |
| nicotinate mononucleotide adenylyltransferase (MtNadD) | Mycobacterium tuberculosis | ATPreleased free phosphate detected colorimetrically | — | 0.041 | 134 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD), ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD) | Mycobacterium tuberculosis | ATP | — | 0.005 | — | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD), ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD) | Mycobacterium tuberculosis | nicotinic acid mononucleotidefollowed at 340 nm | 5.5 | 0.48 | 12 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD), nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD) | Mycobacterium tuberculosis | nicotinic acid mononucleotide | — | 0.48 | — | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD), nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant K47A | Mycobacterium tuberculosis | ATP | — | 0.006 | 3 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant K47A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant K47A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.02 | 2.7 | 0.007 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant K47A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant L164A | Mycobacterium tuberculosis | ATP | — | 0.17 | 0.8 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant L164A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant L164A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.13 | 0.052 | 2.5 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant L164A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant L164Q | Mycobacterium tuberculosis | ATP | — | 0.19 | 0.08 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant L164Q, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant L164Q | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.015 | 0.43 | 0.04 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant L164Q, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant P44A | Mycobacterium tuberculosis | ATP | — | 0.017 | 21 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant P44A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant P44A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.36 | 0.84 | 0.4 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant P44A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant Q46A | Mycobacterium tuberculosis | ATP | — | 0.033 | 142 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant Q46A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant Q46A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 4.7 | 0.33 | 14 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant Q46A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant T12A | Mycobacterium tuberculosis | ATP | — | 0.042 | 5 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant T12A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant T12A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.22 | 0.53 | 0.4 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant T12A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant T86A | Mycobacterium tuberculosis | ATP | — | 0.011 | 18 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant T86A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant T86A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.2 | 2.8 | 0.07 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant T86A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant W117A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.002 | 2.67 | 8 × 10⁻⁴ | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant W117A, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant W117F | Mycobacterium tuberculosis | ATP | — | 0.023 | 1.3 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant W117F, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant W117F | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.03 | 1.13 | 0.03 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant W117F, nicotinic acid mononucleotide | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant W45A | Mycobacterium tuberculosis | ATP | — | 0.011 | 34 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant W45A, ATP | |
| nicotinate mononucleotide adenylyltransferase (MtNadD)variant W45A | Mycobacterium tuberculosis | nicotinic acid mononucleotide | 0.37 | 0.98 | 0.4 | PMID 25631047 | Open record: nicotinate mononucleotide adenylyltransferase (MtNadD) variant W45A, nicotinic acid mononucleotide | |
| nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT) | Plasmodium falciparum | adenosine 5'-triphosphate | 0.082 | 0.525 | 0.17 | pH 7.8, 25 °C | PMID 27984041 | Open record: nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT), adenosine 5'-triphosphate |
| nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT) | Plasmodium falciparum | nicotinamide mononucleotide | 0.087 | 0.04 | 2.2 | pH 7.8, 25 °C | PMID 27984041 | Open record: nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT), nicotinamide mononucleotide |
| nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT) | Plasmodium falciparum | nicotinic acid mononucleotide | 0.065 | 0.022 | 3 | pH 7.8, 25 °C | PMID 27984041 | Open record: nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT), nicotinic acid mononucleotide |
| nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT)variant C41A | Plasmodium falciparum | adenosine 5'-triphosphate | 0.037 | 1.186 | 0.033 | pH 7.8, 25 °C | PMID 27984041 | Open record: nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT) variant C41A, adenosine 5'-triphosphate |
| nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT)variant C41A | Plasmodium falciparum | nicotinamide mononucleotide | 0.075 | 0.753 | 0.1 | pH 7.8, 25 °C | PMID 27984041 | Open record: nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT) variant C41A, nicotinamide mononucleotide |
| nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT)variant C41A | Plasmodium falciparum | nicotinic acid mononucleotide | 0.112 | 0.323 | 0.35 | pH 7.8, 25 °C | PMID 27984041 | Open record: nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT) variant C41A, nicotinic acid mononucleotide |
| nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT)variant C41A/C43A | Plasmodium falciparum | adenosine 5'-triphosphate | 1.92 | 0.456 | 4.2 | pH 7.8, 25 °C | PMID 27984041 | Open record: nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT) variant C41A/C43A, adenosine 5'-triphosphate |
| nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT)variant C41A/C43A | Plasmodium falciparum | nicotinamide mononucleotide | 2.93 | 0.346 | 8.5 | pH 7.8, 25 °C | PMID 27984041 | Open record: nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT) variant C41A/C43A, nicotinamide mononucleotide |
| nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT)variant C41A/C43A | Plasmodium falciparum | nicotinic acid mononucleotide | 2.48 | 0.194 | 12.8 | pH 7.8, 25 °C | PMID 27984041 | Open record: nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT) variant C41A/C43A, nicotinic acid mononucleotide |
| nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT)variant C43A | Plasmodium falciparum | adenosine 5'-triphosphate | 0.7 | 0.624 | 1.2 | pH 7.8, 25 °C | PMID 27984041 | Open record: nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT) variant C43A, adenosine 5'-triphosphate |
| nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT)variant C43A | Plasmodium falciparum | nicotinamide mononucleotide | 1.3 | 0.025 | 52 | pH 7.8, 25 °C | PMID 27984041 | Open record: nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT) variant C43A, nicotinamide mononucleotide |
| nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT)variant C43A | Plasmodium falciparum | nicotinic acid mononucleotide | 1.03 | 0.011 | 93.8 | pH 7.8, 25 °C | PMID 27984041 | Open record: nicotinic acid mononucleotide adenylyltransferase (PfNaMNAT) variant C43A, nicotinic acid mononucleotide |
| NMN/NaMN adenylyltransferase (NadM) | Acinetobacter baylyi | nicotinamide mononucleotide | 4.9 | 0.027 | 180 | PMID 20926389 | Open record: NMN/NaMN adenylyltransferase (NadM), nicotinamide mononucleotide | |
| NMN/NaMN adenylyltransferase (NadM) | Acinetobacter baylyi | nicotinate mononucleotide | 3 | 0.013 | 230 | PMID 20926389 | Open record: NMN/NaMN adenylyltransferase (NadM), nicotinate mononucleotide | |
| NMNAT1 | Homo sapiens | adenosine 5'-triphosphate | — | 0.04 | — | PMID 16118205 | Open record: NMNAT1, adenosine 5'-triphosphate | |
| NMNAT1 | Homo sapiens | nicotinamide adenine dinucleotide (oxidized) | — | 0.059 | — | pH 8 | PMID 16118205 | Open record: NMNAT1, nicotinamide adenine dinucleotide (oxidized) |
| NMNAT1 | Homo sapiens | nicotinamide mononucleotide | — | 0.034 | — | PMID 16118205 | Open record: NMNAT1, nicotinamide mononucleotide | |
| NMNAT1 | Homo sapiens | pyrophosphate | — | 0.937 | — | pH 8 | PMID 16118205 | Open record: NMNAT1, pyrophosphate |
| NMNAT2 | Homo sapiens | adenosine 5'-triphosphate | — | 0.204 | — | PMID 16118205 | Open record: NMNAT2, adenosine 5'-triphosphate | |
| NMNAT2 | Homo sapiens | nicotinamide adenine dinucleotide (oxidized) | — | 0.07 | — | pH 8 | PMID 16118205 | Open record: NMNAT2, nicotinamide adenine dinucleotide (oxidized) |
| NMNAT2 | Homo sapiens | nicotinamide mononucleotide | — | 0.032 | — | PMID 16118205 | Open record: NMNAT2, nicotinamide mononucleotide | |
| NMNAT2 | Homo sapiens | pyrophosphate | — | 1.119 | — | pH 8 | PMID 16118205 | Open record: NMNAT2, pyrophosphate |
| NMNAT3 | Homo sapiens | adenosine 5'-triphosphate | — | 0.029 | — | PMID 16118205 | Open record: NMNAT3, adenosine 5'-triphosphate | |
| NMNAT3 | Homo sapiens | nicotinamide adenine dinucleotide (oxidized) | — | 0.13 | — | pH 8 | PMID 16118205 | Open record: NMNAT3, nicotinamide adenine dinucleotide (oxidized) |
| NMNAT3 | Homo sapiens | nicotinamide mononucleotide | — | 0.209 | — | PMID 16118205 | Open record: NMNAT3, nicotinamide mononucleotide | |
| NMNAT3 | Homo sapiens | pyrophosphate | — | 0.39 | — | pH 8 | PMID 16118205 | Open record: NMNAT3, pyrophosphate |