Values CatLog read from this paper
Structural and functional characterization of M. tuberculosis sedoheptulose- 7-phosphate isomerase, a critical enzyme involved in lipopolysaccharide biosynthetic pathway
PMID 33257730doi:10.1038/s41598-020-77230-8Open in Browse
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CatLog read 14 records (42 values) from this paper: sedoheptulose 7-phosphate isomerase (MtbGmhA) from Mycobacterium tuberculosis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| sedoheptulose 7-phosphate isomerase (MtbGmhA) | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateMichaelis-Menten fit | 0.45 | 0.31 | 1.45 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA), D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA) | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateLineweaver-Burk plot | 0.52 | 0.38 | 1.36 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA), D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA)variant N53G | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateMichaelis-Menten fit | 0.27 | 0.67 | 0.4 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA) variant N53G, D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA)variant N53G | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateLineweaver-Burk plot | 0.27 | 0.62 | 0.43 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA) variant N53G, D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA)variant Q173A | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateMichaelis-Menten fit | 0.1 | 1.53 | 0.06 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA) variant Q173A, D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA)variant Q173A | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateLineweaver-Burk plot | 0.13 | 1.54 | 0.08 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA) variant Q173A, D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA)variant S121G | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateMichaelis-Menten fit | 0.36 | 0.76 | 0.47 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA) variant S121G, D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA)variant S121G | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateLineweaver-Burk plot | 0.33 | 0.73 | 0.45 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA) variant S121G, D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA)variant S123A | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateMichaelis-Menten fit | 0.31 | 0.92 | 0.33 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA) variant S123A, D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA)variant S123A | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateLineweaver-Burk plot | 0.33 | 0.93 | 0.35 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA) variant S123A, D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA)variant S126A | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateMichaelis-Menten fit | 0.19 | 0.83 | 0.22 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA) variant S126A, D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA)variant S126A | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateLineweaver-Burk plot | 0.18 | 0.83 | 0.21 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA) variant S126A, D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA)variant T122A | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateMichaelis-Menten fit | 0.09 | 0.9 | 0.1 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA) variant T122A, D-sedoheptulose 7-phosphate |
| sedoheptulose 7-phosphate isomerase (MtbGmhA)variant T122A | Mycobacterium tuberculosis | D-sedoheptulose 7-phosphateLineweaver-Burk plot | 0.11 | 0.89 | 0.12 | pH 8 | Open record: sedoheptulose 7-phosphate isomerase (MtbGmhA) variant T122A, D-sedoheptulose 7-phosphate |